Cheap flights from Madrid to Upper Middle Rhine Valley

View AU$149 flight on Thu, 9 Oct. 2025Opens in a new window

Popular airlines from Madrid to Upper Middle Rhine Valley

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Madrid (MAD) to Upper Middle Rhine Valley (FRA)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$320 Return, found 1 day ago
AU$320
Return
found 1 day ago
Select Lufthansa flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$320 found 1 day ago
Air Europa
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$363 Return, found 1 day ago
AU$363
Return
found 1 day ago
Select Air Europa flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$363 found 1 day ago
Swiss International Air Lines
Mon, 13 Oct. - Thu, 16 Oct.
MAD
Madrid
FRA
Frankfurt
AU$408 Return, found 6 days ago
AU$408
Return
found 6 days ago
Select Swiss International Air Lines flight, departing Mon, 13 Oct. from Madrid to Frankfurt, returning Thu, 16 Oct., priced at AU$408 found 6 days ago
Brussels Airlines
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$444 Return, found 1 day ago
AU$444
Return
found 1 day ago
Select Brussels Airlines flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$444 found 1 day ago
Air Serbia
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$568 Return, found 1 day ago
AU$568
Return
found 1 day ago
Select Air Serbia flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$568 found 1 day ago
Iberia
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$589 Return, found 1 day ago
AU$589
Return
found 1 day ago
Select Iberia flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$589 found 1 day ago
*Available to Expedia members.