Cheap flights from Madrid to Upper Middle Rhine Valley

View AU$135 flight on Wed, 10 Dec. 2025Opens in a new window

Popular airlines from Madrid to Upper Middle Rhine Valley

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Madrid (MAD) to Upper Middle Rhine Valley (FRA)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Lufthansa
Fri, 22 May - Fri, 29 May
MAD
Madrid
FRA
Frankfurt
AU$250 Return, found 6 days ago
AU$250
Return
found 6 days ago
Select Lufthansa flight, departing Fri, 22 May from Madrid to Frankfurt, returning Fri, 29 May, priced at AU$250 found 6 days ago
Lufthansa
Fri, 22 May - Fri, 29 May
MAD
Madrid
FRA
Frankfurt
AU$286 Return, found 6 days ago
AU$286
Return
found 6 days ago
Select Lufthansa flight, departing Fri, 22 May from Madrid to Frankfurt, returning Fri, 29 May, priced at AU$286 found 6 days ago
Air Europa
Fri, 22 May - Fri, 29 May
MAD
Madrid
FRA
Frankfurt
AU$325 Return, found 6 days ago
AU$325
Return
found 6 days ago
Select Air Europa flight, departing Fri, 22 May from Madrid to Frankfurt, returning Fri, 29 May, priced at AU$325 found 6 days ago
ITA Airways
Fri, 22 May - Fri, 29 May
MAD
Madrid
FRA
Frankfurt
AU$341 Return, found 6 days ago
AU$341
Return
found 6 days ago
Select ITA Airways flight, departing Fri, 22 May from Madrid to Frankfurt, returning Fri, 29 May, priced at AU$341 found 6 days ago
Brussels Airlines
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$375 Return, found 18 hours ago
AU$375
Return
found 18 hours ago
Select Brussels Airlines flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$375 found 18 hours ago
Swiss International Air Lines
Fri, 5 Sep. - Wed, 10 Sep.
MAD
Madrid
FRA
Frankfurt
AU$407 Return, found 18 hours ago
AU$407
Return
found 18 hours ago
Select Swiss International Air Lines flight, departing Fri, 5 Sep. from Madrid to Frankfurt, returning Wed, 10 Sep., priced at AU$407 found 18 hours ago
*Available to Expedia members.