Cheap flights from Madrid to European Side

View AU$140 flight on Thu, 11 Dec. 2025Opens in a new window

Popular airlines from Madrid to European Side

  • Aegean

    Aegean

  • Air France

    Air France

  • ITA Airways

    ITA Airways

  • KLM

    KLM

  • Lufthansa

    Lufthansa

  • LOT-Polish Airlines

    LOT-Polish Airlines

  • Tarom-Romanian Air Transport

    Tarom-Romanian Air Transport

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Cheap Flights from Madrid (MAD) to European Side (IST)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY express
Thu, 5 Feb. - Sun, 8 Feb.
MAD
Madrid
IST
Istanbul
AU$277 Return, found 5 days ago
AU$277
Return
found 5 days ago
Select SKY express flight, departing Thu, 5 Feb. from Madrid to Istanbul, returning Sun, 8 Feb., priced at AU$277 found 5 days ago
Lufthansa
Thu, 11 Dec. - Wed, 17 Dec.
MAD
Madrid
IST
Istanbul
AU$391 Return, found 3 hours ago
AU$391
Return
found 3 hours ago
Select Lufthansa flight, departing Thu, 11 Dec. from Madrid to Istanbul, returning Wed, 17 Dec., priced at AU$391 found 3 hours ago
Aegean
Thu, 11 Dec. - Wed, 17 Dec.
MAD
Madrid
IST
Istanbul
AU$397 Return, found 3 hours ago
AU$397
Return
found 3 hours ago
Select Aegean flight, departing Thu, 11 Dec. from Madrid to Istanbul, returning Wed, 17 Dec., priced at AU$397 found 3 hours ago
Air Europa
Thu, 11 Dec. - Wed, 17 Dec.
MAD
Madrid
IST
Istanbul
AU$487 Return, found 3 hours ago
AU$487
Return
found 3 hours ago
Select Air Europa flight, departing Thu, 11 Dec. from Madrid to Istanbul, returning Wed, 17 Dec., priced at AU$487 found 3 hours ago
Pegasus Airlines
Thu, 11 Dec. - Wed, 17 Dec.
MAD
Madrid
SAW
Istanbul
AU$506 Return, found 3 hours ago
AU$506
Return
found 3 hours ago
Select Pegasus Airlines flight, departing Thu, 11 Dec. from Madrid to Istanbul, returning Wed, 17 Dec., priced at AU$506 found 3 hours ago
KLM
Thu, 11 Dec. - Wed, 17 Dec.
MAD
Madrid
IST
Istanbul
AU$515 Return, found 3 hours ago
AU$515
Return
found 3 hours ago
Select KLM flight, departing Thu, 11 Dec. from Madrid to Istanbul, returning Wed, 17 Dec., priced at AU$515 found 3 hours ago

Find the cheapest month to fly from Madrid (MAD) to Istanbul (IST)

February is typically the cheapest month to fly

From AU$227 - AU$389 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.