Cheap flights from Madrid to European Side

View AU$140 flight on Sun, 7 Dec. 2025Opens in a new window

Popular airlines from Madrid to European Side

  • Aegean

    Aegean

  • Air France

    Air France

  • ITA Airways

    ITA Airways

  • British Airways

    British Airways

  • Sky Express

    Sky Express

  • Air Serbia

    Air Serbia

  • KLM

    KLM

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Cheap Flights from Madrid (MAD) to European Side (IST)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY express
Thu, 5 Feb. - Sun, 8 Feb.
MAD
Madrid
IST
Istanbul
AU$277 Return, found 3 days ago
AU$277
Return
found 3 days ago
Select SKY express flight, departing Thu, 5 Feb. from Madrid to Istanbul, returning Sun, 8 Feb., priced at AU$277 found 3 days ago
Aegean
Fri, 24 Apr. - Sun, 26 Apr.
MAD
Madrid
IST
Istanbul
AU$385 Return, found 4 days ago
AU$385
Return
found 4 days ago
Select Aegean flight, departing Fri, 24 Apr. from Madrid to Istanbul, returning Sun, 26 Apr., priced at AU$385 found 4 days ago
Pegasus Airlines
Tue, 9 Dec. - Thu, 15 Jan.
MAD
Madrid
SAW
Istanbul
AU$408 Return, found 6 days ago
AU$408
Return
found 6 days ago
Select Pegasus Airlines flight, departing Tue, 9 Dec. from Madrid to Istanbul, returning Thu, 15 Jan., priced at AU$408 found 6 days ago
Lufthansa
Tue, 13 Jan. - Sat, 17 Jan.
MAD
Madrid
IST
Istanbul
AU$411 Return, found 6 days ago
AU$411
Return
found 6 days ago
Select Lufthansa flight, departing Tue, 13 Jan. from Madrid to Istanbul, returning Sat, 17 Jan., priced at AU$411 found 6 days ago
Air Europa
Sun, 7 Dec. - Thu, 15 Jan.
MAD
Madrid
IST
Istanbul
AU$486 Return, found 5 days ago
AU$486
Return
found 5 days ago
Select Air Europa flight, departing Sun, 7 Dec. from Madrid to Istanbul, returning Thu, 15 Jan., priced at AU$486 found 5 days ago
KLM
Sun, 7 Dec. - Thu, 15 Jan.
MAD
Madrid
IST
Istanbul
AU$514 Return, found 5 days ago
AU$514
Return
found 5 days ago
Select KLM flight, departing Sun, 7 Dec. from Madrid to Istanbul, returning Thu, 15 Jan., priced at AU$514 found 5 days ago

Find the cheapest month to fly from Madrid (MAD) to Istanbul (IST)

February is typically the cheapest month to fly

From AU$227 - AU$389 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.