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Luxury Hotels & Resorts in Southeast Missouri from AU$140

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Check availability on Southeast Missouri Luxury Hotels

Our top choices for Southeast Missouri luxury hotels

Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (612 reviews)
The price is AU$185
includes taxes & fees
29 June - 30 June
The Riverview
5 restaurants; breakfast, lunch, dinner and brunch served

River City Casino & Hotel

River City Casino & Hotel
4.0 star property
St. Louis
9.2 out of 10, Wonderful, (1,639 reviews)
The price is AU$167
includes taxes & fees
1 July - 2 July
River City Casino & Hotel
Lobby lounge

Drury Plaza Hotel St. Louis Brentwood

Drury Plaza Hotel St. Louis Brentwood
4.0 star property
Brentwood
9.6 out of 10, Exceptional, (1,001 reviews)
The price is AU$234
includes taxes & fees
5 July - 6 July
Drury Plaza Hotel St. Louis Brentwood
Exterior

Hilton St. Louis Frontenac

Hilton St. Louis Frontenac
4.0 star property
Frontenac
8.8 out of 10, Excellent, (1,001 reviews)
  • cleanliness
    Upscale St. Louis retreat features pool, concierge, fine dining in prime business district.
The price is AU$228
includes taxes & fees
5 July - 6 July
Hilton St. Louis Frontenac
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Quick check-in. Room was very clean and nice. Staff was helpful. Would definitely stay here again."
Matt 1-night trip
Posted 3 hours ago
Drury Inn & Suites Sikeston, MO