Photo by Bill Dillard

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5 Dec - 6 Dec
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6 Dec - 7 Dec
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5 Dec - 7 Dec
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12 Dec - 14 Dec

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Top hotels and accommodation in Southeast Missouri

Lobby lounge
Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (848)
"Easy to access and a safe area"
United States
Jesse C.
Travelling with small children
The price is AU$178
includes taxes & fees
7 Dec - 8 Dec
Fairfield Inn & Suites by Marriott Poplar Bluff
Lobby
Motel 6 Poplar Bluff, MO

Motel 6 Poplar Bluff, MO

2.0 star property
Poplar Bluff
7.8 out of 10, Good, (1002)
"Clean room and love that the floors were redone and carpet removed"
United States
Danielle
Travelling for leisure
The price is AU$121
includes taxes & fees
10 Dec - 11 Dec
Motel 6 Poplar Bluff, MO
Exterior
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (1002)
"Beds comfy and room clean"
United States
Jane
Travelling for leisure
The price is AU$162
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Terrace/patio
Hampton Inn Poplar Bluff

Hampton Inn Poplar Bluff

2.5 star property
Poplar Bluff
9.4 out of 10, Exceptional, (796)
"rooms alway nice and clean, and breakfast always good"
United States
Dolores
Travelling for leisure
The price is AU$165
includes taxes & fees
4 Jan - 5 Jan 2026
Hampton Inn Poplar Bluff
Exterior
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

2.5 star property
Sikeston
8.4 out of 10, Very good, (715)
"the towels and linens were clean and fresh smelling"
United States
Roger
Travelling with partner
The price is AU$95
includes taxes & fees
31 Dec - 1 Jan 2026
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1000)
"Pool was clean and looked nice."
United States
Leslie
Travelling for leisure and business
The price is AU$157
includes taxes & fees
9 Dec - 10 Dec
Drury Inn & Suites Sikeston, MO
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (659)
"This is a nice hotel with big rooms."
United States
Donna
Travelling with family
The price is AU$128
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff

3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (955)
"Friendly staff and room was clean."
United States
Emily
Travelling for leisure
The price is AU$176
includes taxes & fees
27 Dec - 28 Dec
Drury Inn & Suites Poplar Bluff
Breakfast, lunch, dinner served; Italian cuisine
Holiday Inn Poplar Bluff by IHG

Holiday Inn Poplar Bluff by IHG

3.0 star property
Poplar Bluff
8.8 out of 10, Excellent, (695)
"Very spacious suite, awesome staff!"
United States
Brittany
Travelling with friends
The price is AU$170
includes taxes & fees
7 Dec - 8 Dec
Holiday Inn Poplar Bluff by IHG
Children’s play area – outdoor
Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View

3.0 star property
Mountain View
8.6 out of 10, Excellent, (331)
"Friendly staff , clean room , thanks!"
United States
Jerry
Travelling solo
The price is AU$157
includes taxes & fees
7 Dec - 8 Dec
Honeysuckle Inn - Mountain View
Lobby
Courtyard by Marriott Cape Girardeau Downtown

Courtyard by Marriott Cape Girardeau Downtown

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (466)
"The downtown location was perfect for us."
United States
Deborah
The price is AU$199
includes taxes & fees
27 Dec - 28 Dec
Courtyard by Marriott Cape Girardeau Downtown
Front of property
Echo Bluff State Park

Echo Bluff State Park

2.5 star property
Eminence
9.6 out of 10, Exceptional, (216)
"It is a lovely property with comfortable beds and spacious rooms."
United States
Nancy
Travelling with family
The price is AU$237
includes taxes & fees
7 Dec - 8 Dec
Echo Bluff State Park
Exterior
Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG

2.5 star property
Perryville
9.2 out of 10, Wonderful, (536)
"Yes our room was great very clean we had everything we needed."
United States
Connie
The price is AU$151
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express & Suites Perryville by IHG
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

2.5 star property
Sikeston
9.0 out of 10, Wonderful, (438)
"Friendly staff, comfortable beds, spacious room (313)."
United States
Julie
Travelling for leisure
The price is AU$163
includes taxes & fees
28 Dec - 29 Dec
Hampton Inn Sikeston
Fridge, microwave, coffee/tea maker
Shepherd Mountain Inn

Shepherd Mountain Inn

2.5 star property
Ironton
9.4 out of 10, Exceptional, (304)
"Comfy bed & clean room & facilities."
United States
Kim
Travelling for leisure
Shepherd Mountain Inn
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

2.5 star property
Sikeston
8.4 out of 10, Very good, (1006)
"The bed was clean and comfortable"
United States
Whitney
Travelling with family
The price is AU$138
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Sikeston
Front of property
The Farmstead Hotel

The Farmstead Hotel

2.5 star property
Caruthersville
8.8 out of 10, Excellent, (460)
"Recently completely renovated, the room was large and very comfortable."
United States
Doreen
Travelling for leisure
The price is AU$137
includes taxes & fees
5 Jan - 6 Jan 2026
The Farmstead Hotel
Lobby
La Quinta Inn & Suites by Wyndham Festus - St. Louis South

La Quinta Inn & Suites by Wyndham Festus - St. Louis South

3.0 star property
Festus
8.0 out of 10, Very good, (883)
"The room was very clean."
United States
Shea
Travelling for business
The price is AU$163
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Festus - St. Louis South
Lobby
Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO

3.0 star property
Jackson
9.6 out of 10, Exceptional, (1002)
"Very comfortable room and bed."
United States
Daral
Travelling with family
The price is AU$133
includes taxes & fees
16 Dec - 17 Dec
Drury Inn & Suites Jackson MO
Outdoor pool, pool loungers
Fort Davidson Hotel

Fort Davidson Hotel

2.5 star property
Ironton
9.2 out of 10, Wonderful, (173)
"Pool very clean and outdoors!"
United States
Rebekah
Travelling for leisure
The price is AU$198
includes taxes & fees
10 Dec - 11 Dec
Fort Davidson Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Great weekend hotel deals in Southeast Missouri, MO

Showing deals for:12 Dec - 14 Dec

Image gallery for Echo Bluff State Park

Front of property

Echo Bluff State Park

2.5 star property
Eminence
9.6/10Exceptional (216 reviews)
7% off
Price is AU$563
for 2 nights, 1 room
AU$281 per night
includes taxes & fees
Echo Bluff State Park
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Stay near popular Central United States attractions

Panorama of Academic Hall, Southeast Missouri State University

Southeast Missouri State University

4.4/5 (137 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
See properties
A huge granite boulder located in Elephant Rocks State Park
Photo by Pat Long
Open Photo by Pat Long

Elephant Rocks State Park

4.8/5 (52 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
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Learn more about Southeast Missouri

Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to Walnut Hollow Lake.

See all hotels in Southeast Missouri
Mini Takes the States 2014 Road Rally Memphis to St.Louis Leg: Moark Regional Railroad Museum HOURS: Saturdays 1 p.m. - 4 p.m. It was not open when I stopped by but there are a few rail cars outside. Poplar has a train rich history. This was a cool little town to stop in and take pictures. Lot's of wall murals for some reason, and some very cool architecture. Worth the stop and be sure and enjoy a lunch at Hayden's Drive-In ! #MTTS2014 #minitakesthestates #go11 #train
Photo by Bill Dillard
Open Photo by Bill Dillard

Top Southeast Missouri Hotel Reviews

Recent Reviews in Southeast Missouri

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

10/10 Excellent
"We like to stay at this hotel on our way to New Orleans and on our return trip to Wisconsin. It is convenient, clean, breakfast options are excellent and the 8 pm cookie time is always a hit. Staff are also very friendly. "
Brian 1-night trip
Posted 2 days ago
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

More cheap accommodation in Southeast Missouri

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO

1625 W Columbia St Farmington MO
The price is AU$94 per night from 18 Dec to 19 Dec
AU$94
18 Dec - 19 Dec
includes taxes & fees
8/10 Very Good! (1,007 reviews)

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