Search Southeast Missouri hotels
Change your mind
Book hotels with free cancellation
Be picky
Search almost a million properties worldwide
Go beyond your typical stay in Southeast Missouri
Farm
Pet friendly
Check prices for these dates
Top hotels and accommodation in Southeast Missouri
The Farmstead Hotel
The Farmstead Hotel
8.8 out of 10, Excellent, (430)
"Very nice place to stay at."
Edina
The price is AU$145
includes taxes & fees
22 Oct - 23 Oct
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MO
9.6 out of 10, Exceptional, (1015)
"This place is everything you would want for the price. "
Gerald
The price is AU$146
includes taxes & fees
26 Oct - 27 Oct
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHG
9.2 out of 10, Wonderful, (521)
"Rooms were clean and everyone was really nice. Only thing I would say is that for the breakfast, the bacon wasn't quite all the way done other than that, a good experience."
TEVIS
The price is AU$196
includes taxes & fees
9 Nov - 10 Nov
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
8.8 out of 10, Excellent, (637)
"We had a restful stay very safe & clean! Friendly staff:)"
Rachel
The price is AU$140
includes taxes & fees
22 Oct - 23 Oct
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference Center
9.6 out of 10, Exceptional, (1019)
"Great place"
Eric
The price is AU$156
includes taxes & fees
26 Oct - 27 Oct
Drury Inn & Suites Hayti Caruthersville
Drury Inn & Suites Hayti Caruthersville
9.4 out of 10, Exceptional, (1004)
"Nice place for a over night stay would recamend."
Terry
The price is AU$165
includes taxes & fees
26 Oct - 27 Oct
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Great weekend hotel deals in Southeast Missouri, MO
Showing deals for:31 Oct - 2 Nov
Image gallery for Tiny Houses of French Village
Tiny Houses of French Village
French Village
10/10Exceptional (3 reviews)
9% off
Price is AU$877
for 2 nights, 1 home
AU$439 per night
includes taxes & fees
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Central United States attractions
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.
Top Southeast Missouri Hotel Reviews
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
More cheap accommodation in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St, Farmington, MO
The price is AU$98 per night from 26 Oct to 27 Oct
AU$98
26 Oct - 27 Oct
includes taxes & fees
8/10 Very Good! (1,019 reviews)
Explore a world of travel with Expedia
- Caravan Parks in Advance
- Holiday Homes in Advance
- Cheap Hotels in Advance
- Hotels with Pool in Advance
- Family Hotels in Annapolis
- Hotels with Pool in Annapolis
- Annapolis Hotels
- B&B in Arcadia
- Caravan Parks in Arcadia
- Holiday Homes in Arcadia
- Hotels with Pool in Arcadia
- Luxury Hotels in Arcadia
- Arcadia Hotels
- Motels in Arcadia
- Belleview Hotels
- Hotels near Big River
- Bismarck Hotels
- Caravan Parks in Black
- Cheap Hotels in Black
- Black Hotels
- Lodges in Black
- Cottages in Bloomfield
- Luxury Hotels in Bloomfield
- Bonne Terre Hotels
- Lodges in Bunker
- Cheap Hotels in Caledonia
- Caledonia Hotels
- Holiday Homes in Des Arc
- Desloge Hotels
- Doe Run Hotels
- Hotels near Elephant Rocks State Park
- Farmstay in Ellington
- Cheap Hotels in Ellington
- Ellington Hotels
- Pet Friendly Hotels in Farmington
- Farmington Hotels
- Flat River Hotels
- Cheap Hotels in Fredericktown
- Fredericktown Hotels
- Motels in Fredericktown
- Cheap Hotels in Jackson
- Hotels with Parking in Jackson
- Luxury Hotels in Jackson
- Hotels near Johnson's Shut-ins State Park
- Junction City Hotels
- B&B in Leadwood
- Leadwood Hotels
- Lesterville Hotels
- Marble Hill Hotels
- Middle Brook Hotels
- Cheap Hotels in New Offenburg
- New Offenburg Hotels
- Farmstay in Park Hills
- Park Hills Hotels
- Cheap Hotels in Patterson
- Patterson Hotels
- Perryville Hotels
- Piedmont Hotels
- Pilot Knob Hotels
- Motels in Pilot Knob
- Hotels with Pool in Poplar Bluff
- Lgbt Welcoming Hotels in Poplar Bluff
- Poplar Bluff Hotels
- Cabin Rentals in Van Buren
- Van Buren Hotels
- Wappapello Hotels
- Flights to Advance
- Flights to Annapolis
- Flights to Belgrade
- Flights to Bismarck
- Flights to Black
- Flights to Caledonia
- Flights to Clearwater
- Flights to Farmington
- Flights to Flat River
- Flights to Greenville
- Flights to Ozora
- Flights to Pilot Knob
- Flights to Poplar Bluff
- Flights to Whitewater
- Flights from Poplar Bluff Municipal
- Flights from Black
- Flights from Dallas (DFW) to Poplar Bluff (POF)
- Flights from London (LON) to Poplar Bluff (POF)
- Flights from San Antonio (SAT) to Poplar Bluff (POF)
- Flights from San Francisco (SFO) to Poplar Bluff (POF)
- Flights from St. Louis (STL) to Poplar Bluff (POF)
- Flights from Sydney (SYD) to Poplar Bluff (POF)
