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21 Aug - 22 AugTomorrow
22 Aug - 23 AugThis weekend
21 Aug - 23 AugNext weekend
28 Aug - 30 AugOur top choices for Southeast Missouri hotels
1. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
Jamie
AU$122
includes taxes & fees
30 Aug - 31 Aug
2. Shepherd Mountain Inn
Shepherd Mountain InnIronton
Katie
AU$189
includes taxes & fees
24 Aug - 25 Aug
3. Fort Davidson Hotel
Fort Davidson HotelIronton
richard
AU$192
includes taxes & fees
26 Aug - 27 Aug
4. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
JANEEN
AU$144
includes taxes & fees
22 Aug - 23 Aug
5. Madison Inn Lodge
Madison Inn LodgeFredericktown
Christine
AU$134
includes taxes & fees
8 Sept - 9 Sept
6. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
Joy
AU$158
includes taxes & fees
30 Aug - 31 Aug
7. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
Philip
AU$147
includes taxes & fees
13 Sept - 14 Sept
8. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
Arsenia
AU$160
includes taxes & fees
30 Aug - 31 Aug
9. Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
Brandy
AU$156
includes taxes & fees
6 Sept - 7 Sept
10. Crown Pointe Lodge, BW Signature Collection
Crown Pointe Lodge, BW Signature CollectionFarmington
Louise
AU$156
includes taxes & fees
30 Aug - 31 Aug
11. Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
Sally
AU$152
includes taxes & fees
30 Aug - 31 Aug
12. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
Joni
AU$161
includes taxes & fees
30 Aug - 31 Aug
13. The Riverview
The RiverviewCape Girardeau
James
AU$168
includes taxes & fees
24 Aug - 25 Aug
14. Perryville RV Resort
Perryville RV ResortPerryville
Von
AU$107
includes taxes & fees
23 Aug - 24 Aug
15. Baymont Inn and Suites by Wyndham Farmington, MO
Baymont Inn and Suites by Wyndham Farmington, MOFarmington
Kellie
AU$89
includes taxes & fees
30 Aug - 31 Aug
16. Super 8 by Wyndham Farmington
Super 8 by Wyndham FarmingtonFarmington
Saundra
AU$91
includes taxes & fees
31 Aug - 1 Sept
17. Hampton Inn Sikeston
Hampton Inn SikestonSikeston
Brandi
AU$155
includes taxes & fees
27 Aug - 28 Aug
18. Black River Motel and Restaurant
Black River Motel and RestaurantLesterville
Douglas
AU$172
includes taxes & fees
25 Aug - 26 Aug
19. Holiday Inn Express & Suites Sikeston Southwest by IHG
Holiday Inn Express & Suites Sikeston Southwest by IHGSikeston
michael
AU$156
includes taxes & fees
20 Sept - 21 Sept
20. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
Gwendolyn
AU$143
includes taxes & fees
30 Aug - 31 Aug
Holiday Rentals in Southeast Missouri
Cabin
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
"I really enjoyed my time at the stay !"
Aparthotel
The Atrium - A Boutique Hotel
The Atrium - A Boutique HotelPerryville
"What an amazing little suite wrapped in a very thought-filled overall venue. Very unique room with a so many details. The overall building with fire pit, game rooms, and local vendor items…all was quite amazing. Every element is thought out very well. It is very convenient and overall comfortable. It was a great getaway."
Cottage
'turtle Rock' - Ironton Cabin w/ Furnished Patio!
'turtle Rock' - Ironton Cabin w/ Furnished Patio!Ironton
"Stroller, pack n play and high chair. This was amazing "
Holiday Home
Tiny Houses of French Village
Tiny Houses of French VillageFrench Village
"Very nice place very clean well kept inside an out it's a nice little romantic getaway they have it set up so great its a must see sunset very relaxing "
Cottage
Walk to Dtwn: Ironton Home in Historic District
Walk to Dtwn: Ironton Home in Historic DistrictIronton
"Clean and comfortable "
Cottage
Walk to Current River: Ozarks Adventure Home!
Walk to Current River: Ozarks Adventure Home!Van Buren
"Teresa & Chuck went out of their way to make the stay EXCELENT. Teresa is a great cook and shared some of her creations with me, again EXCELENT. The lodging was comfortable and easy to access. Next time in town that will be the place for me."
Cottage
Cozy Belgrade Cottage w/ Wood-burning Stove!
Cozy Belgrade Cottage w/ Wood-burning Stove!Belgrade
Cottage
40-acre Poplar Bluff Nature Lovers Paradise!
40-acre Poplar Bluff Nature Lovers Paradise!Poplar Bluff
"Beautiful place enjoyed our stay"
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Stay near popular Southeast Missouri attractions
Photo by Pat Long
Elephant Rocks State Park
9.6/10 (98 reviews)
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
8.8/10 (248 reviews)
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Current River State Park
9.2/10 (20 reviews)
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Century Casino & Hotel Cape Girardeau
8.4/10 (176 reviews)
Why not roll the dice with a visit to Century Casino & Hotel Cape Girardeau during your time in Cape Girardeau? While in this family-friendly area, you can savour the top-notch restaurants.
Century Casino Caruthersville
7.0/10 (57 reviews)
Why not try your luck with a visit to Century Casino Caruthersville during your visit to Caruthersville? While in this family-friendly area, you can enjoy the restaurants.
Learn more about Southeast Missouri
Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from Sam A. Baker State Park to K Bridge Recreation Area.
See all hotels in Southeast Missouri
Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Recent Reviews in Southeast Missouri
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
"Every thing"
The Farmstead Hotel
8/10 Good
"Alyiah was very helpful, professional. On que; while traveling to your astabilment we was running late! Alyiah assure us that our room was still awaiting us. That was a big relief for me. Thanks again Alyiah."
Drury Inn & Suites Hayti Caruthersville
10/10 Excellent
"Enjoyed our stay. Would definitely stay here again."
Fairfield Inn & Suites by Marriott Poplar Bluff
10/10 Excellent
"Great"
Days Inn and Suites by Wyndham Sikeston
10/10 Excellent
"We stay here every time we are in Sikesons. Can't beat this hotel. Super clean 'comfortable!' beds, living room area, and bathrooms. Small hot breakfast. All for the best price out there. Don't skip on this hotel! Staff is always polite and helpful. We always love to walk out to the pond"
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
10/10 Excellent
"Clean room"
Drury Plaza Hotel Cape Girardeau Conference Center
10/10 Excellent
"I love staying at Drury Hotels. Clean rooms , a wonderful Breakfast food and the Staff are always welcoming and offer help. Thank you for Giving my a wonderful nights rest with their cozy pillows and bedding!!!"
Pear Tree Inn Cape Girardeau West
8/10 Good
"A good place. I would stay there again."
Motel 6 Poplar Bluff, MO
8/10 Good
"Clean and nice."
More cheap accommodation in Southeast Missouri
Baymont Inn and Suites by Wyndham Farmington, MO
1625 W Columbia St Farmington MO
AU$89
30 Aug - 31 Aug
includes taxes & fees
Comfort Inn Festus - St Louis South
1303 Veterans Blvd Festus MO
AU$99
10 Sept - 11 Sept
includes taxes & fees
7.8/10 Good! (990 reviews)
Days Inn and Suites by Wyndham Sikeston
220 S Interstate Dr Sikeston MO
AU$101
1 Sept - 2 Sept
includes taxes & fees
7.2/10 Good! (1,003 reviews)
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
AU$124
26 Aug - 27 Aug
includes taxes & fees
8/10 Very good! (1,005 reviews)
The Farmstead Hotel
778 E 3rd St Caruthersville MO
AU$129
23 Aug - 24 Aug
includes taxes & fees
8.6/10 Excellent! (598 reviews)
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
3253 William Street Cape Girardeau MO
AU$166
24 Aug - 25 Aug
includes taxes & fees
9.4/10 Exceptional! (1,005 reviews)
