Photo by Bill Dillard
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Our top choices for Southeast Missouri hotels
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,009 reviews)
"Great place "
Kelly
The price is AU$152
includes taxes & fees
25 Jan - 26 Jan
Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,004 reviews)
"Suited our purpose for overnight on a road trip "
Angela
The price is AU$131
includes taxes & fees
20 Jan - 21 Jan
Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (50 reviews)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
AHMAD
The price is AU$171
includes taxes & fees
29 Jan - 30 Jan
The Farmstead Hotel
The Farmstead HotelCaruthersville
8.8 out of 10, Excellent, (475 reviews)
"Clean room, very nice staff"
Mack
The price is AU$129
includes taxes & fees
20 Jan - 21 Jan
Echo Bluff State Park
Echo Bluff State ParkEminence
9.4 out of 10, Exceptional, (219 reviews)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
Joanne
The price is AU$241
includes taxes & fees
22 Jan - 23 Jan
Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.2 out of 10, Wonderful, (985 reviews)
"Great location and room "
Curtis
The price is AU$176
includes taxes & fees
14 Feb - 15 Feb
The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (492 reviews)
" Excellent stay. Will come again"
joydeep
The price is AU$158
includes taxes & fees
20 Jan - 21 Jan
Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (105 reviews)
"It was a nice stay"
Douglas
The price is AU$152
includes taxes & fees
27 Jan - 28 Jan
Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (715 reviews)
"Amazing place"
Mladen
The price is AU$186
includes taxes & fees
24 Jan - 25 Jan
Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.0 out of 10, Wonderful, (1,001 reviews)
"Very clean and updated bathroom, clean room; outstanding hot breakfast and friendly staff."
Colleen
The price is AU$119
includes taxes & fees
25 Jan - 26 Jan
Motel 6 Poplar Bluff, MO
Motel 6 Poplar Bluff, MOPoplar Bluff
7.8 out of 10, Good, (1,001 reviews)
"Clean room/friendly staff "
Sloan
The price is AU$90
includes taxes & fees
20 Jan - 21 Jan
Drury Inn & Suites Sikeston, MO
Drury Inn & Suites Sikeston, MOSikeston
9.4 out of 10, Exceptional, (1,005 reviews)
"Breakfast was excellent, and fresh. Room was clean and spacious. We enjoyed our brief stay."
Nicole
The price is AU$162
includes taxes & fees
25 Jan - 26 Jan
Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (151 reviews)
"Great hotel - super clean, fast check-in, convenient, etc.
We’ll definitely stay here again. "
Richard
The price is AU$149
includes taxes & fees
29 Jan - 30 Jan
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (553 reviews)
"lean, updated rooms, friendly staff and great breakfast."
Linda
The price is AU$156
includes taxes & fees
25 Jan - 26 Jan
Honeysuckle Inn - Mountain View
Honeysuckle Inn - Mountain ViewMountain View
8.6 out of 10, Excellent, (336 reviews)
"Staff was very friendly."
Joyce
The price is AU$146
includes taxes & fees
25 Jan - 26 Jan
Hampton Inn Sikeston
Hampton Inn SikestonSikeston
9.0 out of 10, Wonderful, (463 reviews)
"Very clean and super friendly staff!"
Katherine
The price is AU$173
includes taxes & fees
1 Feb - 2 Feb
Super 8 By Wyndham Marston
Super 8 By Wyndham MarstonMarston
8.0 out of 10, Very good, (43 reviews)
"Great hotel, great staff"
Dmitry
The price is AU$95
includes taxes & fees
20 Jan - 21 Jan
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (866 reviews)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
Brenda
The price is AU$175
includes taxes & fees
1 Feb - 2 Feb
Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (798 reviews)
"Staff was kind and provided a lot of information during check out."
Shea
The price is AU$176
includes taxes & fees
14 Feb - 15 Feb
Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (482 reviews)
"Very nice hotel!"
Angie
The price is AU$212
includes taxes & fees
1 Feb - 2 Feb
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Holiday Rentals in Southeast Missouri
Cabin
10.0 out of 10, Exceptional, (1 review)
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Discover the family-friendly area of Southeast Missouri—wineries, a scenic riverfront and sights from K Bridge Recreation Area to Lake Wappapello State Park.
Photo by Bill Dillard
Open Photo by Bill Dillard
Top Southeast Missouri Hotel Reviews
Recent Reviews in Southeast Missouri
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
10/10 Excellent
More cheap accommodation in Southeast Missouri
Motel 6 Poplar Bluff, MO
4101 Highway 67 N Poplar Bluff MO
The price is AU$90 per night from 20 Jan to 21 Jan
AU$90
20 Jan - 21 Jan
includes taxes & fees
7.8/10 Good! (1,001 reviews)
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