Southeast Missouri Travel Guide
Tourist Guide
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Drury Plaza Hotel Cape Girardeau Conference Center
3351 Percy Drive Cape Girardeau MO
The price is AU$159 per night from 10 Mar to 11 Mar
AU$159
10 Mar - 11 Mar
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff ...
9.6/10 Exceptional! (1,010 reviews)
My favorite place tpstay when in the area.
Reviewed on 4 Mar 2026
Drury Inn & Suites Cape Girardeau
3303 Campster Drive Cape Girardeau MO
The price is AU$143 per night from 10 Mar to 11 Mar
AU$143
10 Mar - 11 Mar
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the helpful staff and the clean ...
9.4/10 Exceptional! (1,005 reviews)
Great stop. Great facility and food.
Reviewed on 2 Mar 2026
The Riverview
777 Main St Cape Girardeau MO
The price is AU$140 per night from 8 Mar to 9 Mar
AU$140
8 Mar - 9 Mar
includes taxes & fees
Stay at this business-friendly hotel in Cape Girardeau. Enjoy free Wi-Fi, free parking and 2 restaurants. Popular attractions Isle Casino Cape Girardeau and ...
9.4/10 Exceptional! (516 reviews)
Run very well—check in great
Reviewed on 2 Mar 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
7555 State Hwy Y French Village MO
Stay at this cabin in French Village. Enjoy free parking, patios and climate control.
9.8/10 Exceptional! (56 reviews)
Absolutely amazing time as always. Staff is beyond great. Always ready to help and never in the way
Reviewed on 2 Mar 2026
Johnson's Shut-ins State Park
148 Taum Sauk Trail Middle Brook MO
Stay at this cabin in Middle Brook. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Popular attractions Johnson's Shut-ins State Park and Taum Sauk ...
10/10 Exceptional! (1 review)
These newer cabins are clean and have everything you need. Highly recommend!
Reviewed on 5 Nov 2025
"Little Brick House on Main (1865)”
Ste. Genevieve MO
Stay at this holiday home in Ste Genevieve. Enjoy patios, an in-room coffee maker and air conditioning. Popular attractions Felix Valle House State Historic ...
10/10 Exceptional! (67 reviews)
Great, cute place conveniently located. Thoughtfully designed with everything we needed.
Reviewed on 18 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Check Southeast Missouri hotel availability
Popular places to visit
Elephant Rocks State Park
You can take time to visit Elephant Rocks State Park during your travels to Ironton. While you're in the area, wander around the parks.
Southeast Missouri State University
Take a campus tour or just explore the area of Southeast Missouri State University during your trip to Cape Girardeau. While in this family-friendly area, you can savour the top-notch restaurants.
Lake Wappapello
Commune with nature and explore the great outdoors at Lake Wappapello during your travels in Wappapello. While in this family-friendly area, you can enjoy the restaurants.
Current River State Park
Commune with nature and explore the great outdoors at Current River State Park during your travels in Salem. While you're in the area, stroll along the riverfront.
Big Spring
Enjoy an outing to Big Spring during your stay in Van Buren. Wander the forests and riverfront while you're in the area.
Hawn State Park
You can take time to visit Hawn State Park during your travels to Ste Genevieve. Discover the area's cafes or seek out the golf courses.
Activities
Night Ghost Tour of Pythian Castle in Springfield Missouri
AU$28
per adult
100% of travellers recommend
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