Business Hotels & Resorts in Southeast Missouri from AU$91

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Check availability on Southeast Missouri Business Hotels

Our top choices for Southeast Missouri business-friendly hotels

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Drury Inn & Suites Jackson MO

Drury Inn & Suites Jackson MO
3.0 star property
Jackson
9.6 out of 10, Exceptional, (1,004 reviews)
"Clean room, friendly staff, good breakfast and dinner variety,large open parking, clean pool and exercise room. All around great stay. "
United States
Jeremy
The price is AU$121
includes taxes & fees
28 May - 29 May
Drury Inn & Suites Jackson MO
Front of property

Echo Bluff State Park

Echo Bluff State Park
2.5 star property
Eminence
9.4 out of 10, Exceptional, (249 reviews)
"Always a wonderful experience when staying here"
United States
James
The price is AU$265
includes taxes & fees
20 May - 21 May
Echo Bluff State Park
Lobby

Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau
3.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (184 reviews)
"Nice room, good breakfast "
United States
KENNETH
The price is AU$146
includes taxes & fees
28 May - 29 May
Fairfield Inn & Suites by Marriott Cape Girardeau
Lobby

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center
3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1,004 reviews)
"We found this property to be everything someone would hope for in an overnight stay away from home."
United States
Richard
The price is AU$158
includes taxes & fees
31 May - 1 June
Drury Plaza Hotel Cape Girardeau Conference Center
Hiking

Honeysuckle Inn - Mountain View

Honeysuckle Inn - Mountain View
3.0 star property
Mountain View
8.6 out of 10, Excellent, (353 reviews)
"We stayed one night. For a small town, it's a decent Inn to stay. Could there be updates to the rooms, yes, but overall it was okay. Will we stay again? Unsure."
United States
Wanda
The price is AU$145
includes taxes & fees
19 May - 20 May
Honeysuckle Inn - Mountain View
Lobby

Drury Inn & Suites Poplar Bluff

Drury Inn & Suites Poplar Bluff
3.0 star property
Poplar Bluff
9.2 out of 10, Wonderful, (1,003 reviews)
"Great place to stay. Clean, great staff and the food is good. Would stay again."
United States
Stephanie
The price is AU$148
includes taxes & fees
7 June - 8 June
Drury Inn & Suites Poplar Bluff
Lobby sitting area

The Riverview

The Riverview
4.0 star property
Cape Girardeau
9.4 out of 10, Exceptional, (572 reviews)
"I ALWAYS stay here when I come to Cape! Wonderful, great place!"
United States
Audra
The price is AU$186
includes taxes & fees
18 May - 19 May
The Riverview
Exterior

Holiday Inn Express & Suites Perryville by IHG

Holiday Inn Express & Suites Perryville by IHG
2.5 star property
Perryville
9.2 out of 10, Wonderful, (585 reviews)
"Breakfast was great. Fresh coffee, pancake maker so good. "
United States
Kristin
The price is AU$162
includes taxes & fees
24 May - 25 May
Holiday Inn Express & Suites Perryville by IHG
Free daily buffet breakfast

Baymont Inn and Suites by Wyndham Farmington, MO

Baymont Inn and Suites by Wyndham Farmington, MO
2.5 star property
Farmington
8.0 out of 10, Very good, (1,002 reviews)
"Very nice, clean, friendly staff"
United States
Patty
The price is AU$91
includes taxes & fees
24 May - 25 May
Baymont Inn and Suites by Wyndham Farmington, MO
Lobby lounge

Fairfield Inn & Suites by Marriott Poplar Bluff

Fairfield Inn & Suites by Marriott Poplar Bluff
3.0 star property
Poplar Bluff
9.4 out of 10, Exceptional, (902 reviews)
"Nice overnight stop over"
United States
Douglas
The price is AU$174
includes taxes & fees
20 May - 21 May
Fairfield Inn & Suites by Marriott Poplar Bluff
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Southeast Missouri Hotel Reviews

Best Western Plus Sikeston I-55

Best Western Plus Sikeston I-55

10/10 Excellent
"Best Best Western Plus that I have been to in a long time. The breakfast staff was exceptionally helpful and they had an above average breakfast, including hot water for tea and a single serving coffee maker to use my own coffee (yes, I bring it just in case). So very awesome. The room was comfortable and roomy. We will definitely be staying here again."
Maria 1-night trip
Posted 1 hour ago
Best Western Plus Sikeston I-55

Frequently asked questions

How much do business-friendly hotels in Southeast Missouri cost?
Prices for business hotels in Southeast Missouri range between AU$91 and AU$265 per night. Whatever your budget, Expedia is here to help you find the ideal space for a successful work trip. This price was available on Expedia within the past 7 days, for a hotel booking with a check-in date within the next year. Prices reflect current offers and availability is subject to change. Additional terms may apply.
How many business-friendly hotels are there in Southeast Missouri?
Southeast Missouri has 50 business-friendly hotels to pick from. Whether you're attending a conference or meeting or simply working remotely, these stays have the amenities you need to keep you productive and comfortable.
What is there to do in Southeast Missouri near my business-friendly hotel?
The best travel accessory for your Southeast Missouri work trip is an awesome itinerary for when you have some free time! Isle Casino Cape Girardeau, Cape Rock Park and Fort D Historic Site are some of the leading sights if you're headed to Cape Girardeau. Ste Genevieve also has plenty of superb attractions, such as Sainte Genevieve Winery, Bolduc House Museum and Felix Valle House State Historic Site.

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