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Adults Only & Resorts in Southeast Missouri from AU$94
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Recommended hotels in Southeast Missouri
9.4 out of 10, Exceptional, (1001)
"Great place. Friendly staff clean"
Jeff
The price is AU$154
includes taxes & fees
5 Jan - 6 Jan 2026
Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1002)
"This Drury is our preferred place to stay when visiting family in Cape Girardeau. The hotel Staff is always warm and small town friendly! The hotel is nice and the breakfast buffet is outstanding!! "
Michael
The price is AU$152
includes taxes & fees
6 Jan - 7 Jan 2026
8.8 out of 10, Excellent, (708)
"Amazing place"
Mladen
The price is AU$186
includes taxes & fees
8 Jan - 9 Jan 2026
9.6 out of 10, Exceptional, (217)
"The cabin was beautiful, comfy, & private! The park was FANTASTIC for hiking & scenery! We hope to return and maybe bring family or friends. The staff were all friendly too! :)"
Joanne
The price is AU$241
includes taxes & fees
1 Jan - 2 Jan 2026
8.8 out of 10, Excellent, (466)
"Clean room, very nice staff"
Mack
The price is AU$145
includes taxes & fees
9 Jan - 10 Jan 2026
9.2 out of 10, Wonderful, (972)
"Nice room helpful staff. "
Deborah
The price is AU$179
includes taxes & fees
10 Jan - 11 Jan 2026
Holiday Inn Express & Suites Perryville by IHG
Holiday Inn Express & Suites Perryville by IHGPerryville
9.2 out of 10, Wonderful, (547)
"lean, updated rooms, friendly staff and great breakfast."
Linda
The price is AU$156
includes taxes & fees
25 Jan - 26 Jan 2026
Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (861)
"The size of the room. The staff were great. The room was very clean. Will definitely stay there again."
Brenda
The price is AU$175
includes taxes & fees
9 Jan - 10 Jan 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
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