Photo by Bill Dillard
Holiday Homes in Southeast Missouri
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check prices for these dates
In two weeks
In two months
In three months
In four months
Our top choices for Southeast Missouri holiday homes
Holiday Home in French Village
Tiny Houses of French Village10.0 out of 10, Exceptional, (3 reviews)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
Norma
Holiday Home in Van Buren
Charming 2-bedroom house with AC, WiFi in serene Van Buren9.0 out of 10, Wonderful, (15 reviews)
"It was beautiful and homey. We really enjoyed our stay. "
Jessica
The price is AU$243
includes taxes & fees
9 Mar - 10 Mar
Holiday Home in Farmington
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington10.0 out of 10, Exceptional, (13 reviews)
"Beyond our expectations, nextwe are in Farmington we will stay again. Very Charming in a convenient location. Host made are stay very enjoyable."
Unspecified U.
The price is AU$343
includes taxes & fees
8 Mar - 9 Mar
Holiday Home in Ellsinore
Get Away Acres 1/2 mile off highway 60 extra sanitized10.0 out of 10, Exceptional, (95 reviews)
"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"
Anonymous traveller
The price is AU$189
includes taxes & fees
9 Mar - 10 Mar
Holiday Home in Farmington
Cozy 1-bedroom house with AC and WiFi in charming Farmington10.0 out of 10, Exceptional, (9 reviews)
"Beautiful and perfect for travelers!!!!!"
Elizabeth
The price is AU$274
includes taxes & fees
8 Mar - 9 Mar
Holiday Home in Cape Girardeau
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool8.8 out of 10, Excellent, (39 reviews)
"Very nice house. The pool and hot tub were perfect for a short getaway. Tons of activities and games to keep the fanily entertained. Will definitely come back! "
Emily D.
The price is AU$314
includes taxes & fees
8 Mar - 9 Mar
Holiday Home in Farmington
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC10.0 out of 10, Exceptional, (8 reviews)
"It is a very nice place and very comfortable has everything you could possibly need for homeaway from home."
Scott
The price is AU$343
includes taxes & fees
13 Mar - 14 Mar
Holiday Home in Bonne Terre
Clifford's Country Cottage10.0 out of 10, Exceptional, (27 reviews)
"Wife just loved the place"
Stanley H.
The price is AU$220
includes taxes & fees
9 Mar - 10 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Find holiday rentals that suit your style
Cabins
Private holiday homes
Save an average of 15% on thousands of hotels when you're signed in
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Sikeston, MO
10/10 Excellent
Find out more about Southeast Missouri
Southeast Missouri Holiday Homes information
Number of reviews | 404 |
|---|---|
Accommodation | 190 Holiday Homes |
Lowest Price | AU$189 |
Highest Price | AU$394 |
Explore a world of travel with Expedia
- Caravan Parks in Advance
- Holiday Homes in Advance
- Cheap Hotels in Advance
- Hotels with Pool in Advance
- Family Hotels in Annapolis
- Hotels with Pool in Annapolis
- Annapolis Hotels
- B&B in Arcadia
- Caravan Parks in Arcadia
- Holiday Homes in Arcadia
- Hotels with Pool in Arcadia
- Luxury Hotels in Arcadia
- Arcadia Hotels
- Motels in Arcadia
- Belleview Hotels
- Holiday Homes in Bernie
- Hotels near Big River
- Bismarck Hotels
- Caravan Parks in Black
- Cheap Hotels in Black
- Black Hotels
- Lodges in Black
- Cottages in Bloomfield
- Bonne Terre Hotels
- Lodges in Bunker
- Cheap Hotels in Caledonia
- Caledonia Hotels
- Motels in Cape Girardeau
- Holiday Homes in Des Arc
- Desloge Hotels
- Doe Run Hotels
- Hotels near Elephant Rocks State Park
- Farmstay in Ellington
- Cheap Hotels in Ellington
- Ellington Hotels
- Motels in Eminence
- Pet Friendly Hotels in Farmington
- Farmington Hotels
- Flat River Hotels
- Cheap Hotels in Fredericktown
- Fredericktown Hotels
- Motels in Fredericktown
- Farmstay in French Village
- Holiday Homes in French Village
- Lodges in French Village
- Hotels near Johnson's Shut-ins State Park
- Junction City Hotels
- B&B in Leadwood
- Leadwood Hotels
- Lesterville Hotels
- Marble Hill Hotels
- Middle Brook Hotels
- Cheap Hotels in New Offenburg
- New Offenburg Hotels
- Inns in Oran
- Farmstay in Park Hills
- Park Hills Hotels
- Cheap Hotels in Patterson
- Patterson Hotels
- Perryville Hotels
- Piedmont Hotels
- Pilot Knob Hotels
- Motels in Pilot Knob
- Motels in Potosi
- Motels in Qulin
- B&B in St Mary
- Caravan Parks in St Mary
- B&B in Ste Genevieve
- Cabin Rentals in Van Buren
- Van Buren Hotels
- Wappapello Hotels
- Motels in Winona
- Flights to Advance
- Flights to Annapolis
- Flights to Belgrade
- Flights to Bismarck
- Flights to Black
- Flights to Caledonia
- Flights to Clearwater
- Flights to Farmington
- Flights to Flat River
- Flights to Greenville
- Flights to Pilot Knob
- Flights to Whitewater
- Flights from Poplar Bluff Municipal
- Flights from Black
- Flights from Dallas (DFW) to Poplar Bluff (POF)
- Flights from San Antonio (SAT) to Poplar Bluff (POF)
- Flights from San Francisco (SFO) to Poplar Bluff (POF)
- Flights from St. Louis (STL) to Poplar Bluff (POF)
- Flights from Sydney (SYD) to Poplar Bluff (POF)