Holiday Homes in Southeast Missouri

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Next weekend
24 Oct - 26 Oct
In two weeks
31 Oct - 2 Nov
In one month
14 Nov - 16 Nov
In two months
12 Dec - 14 Dec

Featured Holiday Homes in Southeast Missouri

House | Living area
Tiny Houses of French Village
Tiny Houses of French Village
2.5 star property
10.0 out of 10, Exceptional, (3)
"Charming property with a space for everything and everything in its place. Would not hesitate to recommend or stay again."
United States
Norma
Tiny Houses of French Village
Smart TV
In-law Suite
In-law Suite
9.8 out of 10, Exceptional, (14)
"Well taken care of, nice amenities, comfortable."
United States
Daniel K.
The price is AU$318
includes taxes & fees
20 Oct - 21 Oct
In-law Suite
Outdoor dining
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
2.0 star property
10.0 out of 10, Exceptional, (9)
"This is a darling house and very comfortable."
United States
Stephanie B.
The price is AU$355
includes taxes & fees
19 Oct - 20 Oct
"The Hideaway 1" Charming 2-bedroom house with WiFi, AC in fabulous Farmington
Private kitchen
Cozy 1-bedroom house with AC and WiFi in charming Farmington
Cozy 1-bedroom house with AC and WiFi in charming Farmington
10.0 out of 10, Exceptional, (5)
"The place was very clean and had everything we needed. Will stay there again "
United States
Amy B.
The price is AU$285
includes taxes & fees
22 Oct - 23 Oct
Cozy 1-bedroom house with AC and WiFi in charming Farmington
Interior
Charming 2-bedroom house with AC, WiFi in serene Van Buren
Charming 2-bedroom house with AC, WiFi in serene Van Buren
2.0 star property
9.0 out of 10, Wonderful, (15)
"It was beautiful and homey. We really enjoyed our stay. "
United States
Jessica
The price is AU$262
includes taxes & fees
20 Oct - 21 Oct
Charming 2-bedroom house with AC, WiFi in serene Van Buren
Outdoor dining
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
2.0 star property
10.0 out of 10, Exceptional, (7)
"The place was just the right size for my son and I. Very clean and comfortable. Pretty quiet for being in the middle of town. Would stay here again. "
United States
Kimberly
The price is AU$352
includes taxes & fees
21 Oct - 22 Oct
"The Hideaway 2" Charming 2-bedroom house in delightful Farmington with WiFi, AC
Exterior
The Morning Glory - Country Cottage
The Morning Glory - Country Cottage
10.0 out of 10, Exceptional, (2)
"Great stay. Home was just as advertised. Great communication with owner. Will visit again. "
United States
Scott C.
The price is AU$364
includes taxes & fees
19 Oct - 20 Oct
The Morning Glory - Country Cottage
Property grounds
Get Away Acres 1/2 mile off highway 60 extra sanitized
Get Away Acres 1/2 mile off highway 60 extra sanitized
10.0 out of 10, Exceptional, (94)
"We really enjoyed our stay! Host was very friendly and quick to respond to questions! We will definitely stay again!!"
United States
Anonymous traveller
The price is AU$213
includes taxes & fees
20 Oct - 21 Oct
Get Away Acres 1/2 mile off highway 60 extra sanitized
Fridge, microwave, oven, stovetop
Cozy Three bedroom home in Central Farmington
Cozy Three bedroom home in Central Farmington
9.6 out of 10, Exceptional, (29)
"Was in town for a junior golf tournament and this place we perfect! Very clean, updated and comfortable. Nice quiet neighborhood. Would definitely stay again!"
United States
Jason K.
The price is AU$384
includes taxes & fees
19 Oct - 20 Oct
Cozy Three bedroom home in Central Farmington
Fridge, microwave, oven, stovetop
Clifford's Country Cottage
Clifford's Country Cottage
2.5 star property
10.0 out of 10, Exceptional, (23)
"Great place to stayLove the interiorPerfect set up for what we needed"
United States
Adrienne N.
The price is AU$238
includes taxes & fees
20 Oct - 21 Oct
Clifford's Country Cottage
Beach
Your home away from home in downtown, historic Farmington!
Your home away from home in downtown, historic Farmington!
10.0 out of 10, Exceptional, (33)
"Great place to rest a recoup for weekend activities "
United States
Matt B.
The price is AU$331
includes taxes & fees
19 Oct - 20 Oct
Your home away from home in downtown, historic Farmington!
Living area
Modern Newly built 2-bedroom house minutes from downtown Park Hills
Modern Newly built 2-bedroom house minutes from downtown Park Hills
10.0 out of 10, Exceptional, (4)
"Stayed here as it was close to our newly purchased home. The home was comfortable and quiet. "
United States
Greg S.
The price is AU$318
includes taxes & fees
20 Oct - 21 Oct
Modern Newly built 2-bedroom house minutes from downtown Park Hills
Dining
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.
10.0 out of 10, Exceptional, (5)
"What a beautiful fun stay that was a nice quick getaway for us! Everything was perfect from booking, to arrival, to overall stay, we had the best time! "
United States
Blake H.
The price is AU$403
includes taxes & fees
20 Oct - 21 Oct
Goforth into Nature, a charming 1-bdrm home in the quiet Bloomsdale countryside.
2 bedrooms, iron/ironing board, free WiFi, bed sheets
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
8.4 out of 10, Very good, (7)
"Enjoyed our stay at Andy’s place! It had everything we needed. Beds were super comfy and the water pressure in the showers was great. Nice, safe location. Easy to get to/from places. Place has a garage which we used one evening during a rain storm but otherwise felt completely safe leaving our vehicle on driveway overnight. We didn’t get a chance to use the nice deck area with bbq grill but this is definitely a great feature of the property. The large tv in the living room was a hit with my...
Canada
Holly R.
The price is AU$399
includes taxes & fees
24 Oct - 25 Oct
Charming 2-bedroom house with 2 KING BEDS in Pleasant Poplar Bluff
Exterior
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
8.8 out of 10, Excellent, (34)
"Abbie was an amazing hostess. She was great with communicating with our group and made our stay awesome. She was very accommodating and made sure we had everything we needed to make our trip perfect. The house and pool were great. We were very pleased. "
United States
Julie H.
The price is AU$330
includes taxes & fees
19 Oct - 20 Oct
3+ acre Home: Pool Table, Putt-Putt, 4 miles to Downtown and SEMO, Summer Pool
Fridge, microwave, oven, stovetop
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
8.6 out of 10, Excellent, (4)
"Great place. "
United States
Diana
The price is AU$226
includes taxes & fees
10 Nov - 11 Nov
Charming 1-bd house in Downtown Farmington, 1block from Police & Fire stations
Property grounds
Doc's Cottage - A-Frame in Piggott, AR
Doc's Cottage - A-Frame in Piggott, AR
10.0 out of 10, Exceptional, (8)
"Great place to spend time with our daughter who lives in Piggott. The home was rustic and had all the amenities that was needed for an enjoyable stay.When your in the backyard it was secluded and quite even though you were in town."
United States
Kathy D.
The price is AU$356
includes taxes & fees
19 Oct - 20 Oct
Doc's Cottage - A-Frame in Piggott, AR
Exterior detail
"Little Brick House on Main (1865)”
"Little Brick House on Main (1865)”
10.0 out of 10, Exceptional, (56)
"Great place to stay!"
United States
Lettitia B.
The price is AU$248
includes taxes & fees
19 Oct - 20 Oct
"Little Brick House on Main (1865)”
Property grounds
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
2.0 star property
9.8 out of 10, Exceptional, (20)
"This property worked well for our needs. Very convenient location to gas, food and golf course. "
United States
Jill B.
The price is AU$391
includes taxes & fees
3 Nov - 4 Nov
Newly remodeled house minutes away from downtown, golf courses + BIG back yard
Dining
Cute town house with fenced backyard
Cute town house with fenced backyard
9.6 out of 10, Exceptional, (17)
"It was a great place to stay for our needs we had our little dog with us as was there for weekend, it had a nice fenced back yard we could let her just go out didn't have to have her on leash. Was very nice inside clean well kept, beds were surprising comfortable. The host stayed in contact and answered a lot questions before we arrived which put me a ease for our trip. High recommand this place if needing to stay in the area. "
United States
Terry
The price is AU$399
includes taxes & fees
26 Oct - 27 Oct
Cute town house with fenced backyard
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Top Southeast Missouri Hotel Reviews

Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

10/10 Excellent
"Clean. Happy hour at 530, decent breakfast options "
Agnieszka 1-night trip
Posted 2 days ago
Drury Inn & Suites Sikeston, MO

Find out more about Southeast Missouri

Southeast Missouri Holiday Homes information

Number of reviews
Accommodation
 Holiday Homes
Lowest Price
Highest Price

Explore a world of travel with Expedia