South Central Houston Hotels, Houston

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2 Aug - 3 Aug
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1143 Cheap Hotels in South Central Houston - Specials, Reviews, & Last Minute Deals

Hilton Houston Plaza/Medical Center
Relax by the pool surrounded by lounge chairs and sunbeds, with a clear view of the adjacent building.

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very good, (1489)
"Nice hotel and perfectly located "
The price is AU$167
includes taxes & fees
1 Sept - 2 Sept
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG
Welcome to our reception area, featuring a minimalist design with a reception desk, vertical garden, and comfortable seating.

InterContinental Houston by IHG

4.0 star property
9.2 out of 10, Wonderful, (1001)
"Very good hotel for visits to mD Anderson. Excellent facility and staff"
The price is AU$289
includes taxes & fees
2 Sept - 3 Sept
InterContinental Houston by IHG
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Enjoy a diverse selection of food at our self-service buffet.

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.4 out of 10, Very good, (402)
"Very nice place clean nice towels good shower"
The price is AU$208
includes taxes & fees
10 Aug - 11 Aug
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Hotel Zaza Houston Museum District
Enjoy city views from the large window, relax in the plush armchair, and unwind with a good night's sleep on the classic bed.

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1733)
"Had a quick stay here and would come back again!"
Hotel Zaza Houston Museum District
The Westin Houston Medical Center/Museum District
Relax by the rooftop pool, surrounded by lounge chairs and umbrellas.

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1003)
"Always a great stay here"
The price is AU$263
includes taxes & fees
9 Aug - 10 Aug
The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Relax in a stylish lounge area with a curved sofa, armchairs, and a coffee table.

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1005)
"Peaceful and relaxing stay."
The price is AU$309
includes taxes & fees
9 Aug - 10 Aug
Houston Marriott Medical Center/Museum District
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Relax in the hotel's spacious lobby, featuring a mezzanine level, comfortable seating areas, and a flat-screen TV.

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1002)
"Very clean and peaceful place to stay close to the hospital 🏥 "
The price is AU$148
includes taxes & fees
22 Aug - 23 Aug
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Americas Best Value Inn Medical Center Downtown
Two beds with matching headboards and footboards, a nightstand, and a bedside table with a lamp.

Americas Best Value Inn Medical Center Downtown

2.0 star property
7.8 out of 10, Good, (1000)
"Highly recommended.. I will stay again."
The price is AU$135
includes taxes & fees
3 Aug - 4 Aug
Americas Best Value Inn Medical Center Downtown
Wanderstay Houston Hostel
Welcome to our lobby, where a vibrant cityscape mural and cozy seating area create a warm atmosphere.

Wanderstay Houston Hostel

2.0 star property
8.4 out of 10, Very good, (184)
"This is an amazing place to stay."
The price is AU$108
includes taxes & fees
3 Aug - 4 Aug
Wanderstay Houston Hostel
La Maison in Midtown an urban B&B
Residents enjoy balconies and a secure, well-maintained outdoor space.

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (515)
"Nice property we are enjoying our stay. "
The price is AU$307
includes taxes & fees
3 Aug - 4 Aug
La Maison in Midtown an urban B&B
Hilton University of Houston
Two large beds with grey headboards and white bedding, a desk and chair, and a balcony with city views.

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (848)
"Awesome Hotel. "
The price is AU$275
includes taxes & fees
8 Aug - 9 Aug
Hilton University of Houston
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Enjoy a balcony with potted plants and a view of the pool surrounded by a garden.

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (190)
"This was a wonderful place to stay!!"
The price is AU$387
includes taxes & fees
7 Aug - 8 Aug
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Rodeway Inn & Suites Houston near Medical Center
Compact living space with a kitchenette, sofa, and coffee table.

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (475)
"It was affordable and comfortable. "
The price is AU$95
includes taxes & fees
31 Aug - 1 Sept
Rodeway Inn & Suites Houston near Medical Center
Spacious Houston 3bed3 Bath Family Townhome
Enjoy cooking in this well-equipped kitchen with a central island and stainless steel appliances.

Spacious Houston 3bed3 Bath Family Townhome

2.0 star property
8.0 out of 10, Very good, (1)
"The property was clean and new it was nice. Top Terrace in the downtown view was breathtaking they do have a elevator but there was no access to it we had to climb 4 floors. the garage door opener was not working also the garage door close and open on its own after a couple of minutes they put only one face towel and one napkin for bathroom if there is a two people per bedroom they should at least provide Two Face towels and two napkins. In the master bathroom there was only one small rug in...
The price is AU$571
includes taxes & fees
14 Aug - 15 Aug
Spacious Houston 3bed3 Bath Family Townhome
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (40)
"Great stay!"
The price is AU$219
includes taxes & fees
3 Aug - 4 Aug
Wanderstay Boutique Hotel
Southmore Boulevard Motel
Relax in a spacious room with a large bed, desk, and mirror.

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (216)
"Good area"
The price is AU$117
includes taxes & fees
3 Aug - 4 Aug
Southmore Boulevard Motel
Modern Cozy Home with King Bed
Enjoy cooking in this well-equipped kitchen with a stainless steel refrigerator, oven, and ample counter space.

Modern Cozy Home with King Bed

3.5 star property
9.6 out of 10, Exceptional, (19)
"Very spacious and close to just about everything. The view is amazing too"
The price is AU$538
includes taxes & fees
10 Aug - 11 Aug
Modern Cozy Home with King Bed
Luxurious 3 Bed3 Bath Near Downtown Houston
Relax in this stylish living room with a balcony offering views of the surrounding neighborhood.

Luxurious 3 Bed3 Bath Near Downtown Houston

2.0 star property
10.0 out of 10, Exceptional, (1)
"This was made for a perfect family vacation… super clean kid friendly with an awesome view of Houston for the adults on rooftop "
The price is AU$528
includes taxes & fees
5 Aug - 6 Aug
Luxurious 3 Bed3 Bath Near Downtown Houston
Paradise Palace Best Rooftop in HTX w Hot Tub
Enjoy a meal in the kitchen with a central island and oven, microwave, and large window offering a view of the outdoors.

Paradise Palace Best Rooftop in HTX w Hot Tub

3.0 star property
Paradise Palace Best Rooftop in HTX w Hot Tub
The Green Haus Luxxe Cabana Rooftop Retreat
Relax in a shaded outdoor space with a sofa set, wicker chair, and hanging chair, surrounded by a cityscape.

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The price is AU$1,066
includes taxes & fees
5 Aug - 6 Aug
The Green Haus Luxxe Cabana Rooftop Retreat
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Our guide on where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green which includes a high-rise building, a square or plaza and a city
Downtown Houston map

Downtown Houston

Gourmet restaurants acclaimed theatres and top sights from Toyota Center to Daikin Park – discover Downtown Houston, a destination also famous for its sports teams.

The Galleria map

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Gerald D. Hines Waterwall Park.

Texas Medical Center map

Texas Medical Center

2 out of top 10 points of interest in this area

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection showing interior views and art
Montrose map

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Westheimer Rd while you're exploring the area.

Houston showing a high-rise building and a city
Houston Central Business District map

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Central Houston Hotel Reviews

Hilton University of Houston

Hilton University of Houston

10/10 Excellent
"Friendly, welcoming staff. The beds are really comfortable and the a/c works great. "
Luis 1-night trip
Posted 2 days ago
Hilton University of Houston

Frequently asked questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other top choices in the neighbourhood include La Maison in Midtown an urban B&B and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1148 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, James Turrell's Twilight Epiphany Skyscape and Cullen Sculpture Garden. Houston Zoo and Children's Museum of Houston are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.