South Central Houston Hotels, Houston

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27 Sept - 28 Sept
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28 Sept - 29 Sept
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3 Oct - 5 Oct
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10 Oct - 12 Oct

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1155 Cheap Hotels in South Central Houston - Specials, Reviews, & Last Minute Deals

Hilton Houston Plaza/Medical Center
Sun deck

Hilton Houston Plaza/Medical Center

4.5 star property
8.4 out of 10, Very good, (1609)
"Very nice staff, enjoyed our stay"
The price is AU$172
includes taxes & fees
12 Oct - 13 Oct
Hilton Houston Plaza/Medical Center
InterContinental Houston by IHG
Reception

InterContinental Houston by IHG

4.0 star property
9.4 out of 10, Exceptional, (1019)
"Awesome location. "
The price is AU$308
includes taxes & fees
5 Oct - 6 Oct
InterContinental Houston by IHG
Hotel Zaza Houston Museum District
1 bedroom, premium bedding, pillow-top beds, minibar

Hotel Zaza Houston Museum District

4.5 star property
9.0 out of 10, Wonderful, (1783)
"Great stay at Hotel Zaza. The staff is amazing, accommodating, friendly, helpful!"
The price is AU$540
includes taxes & fees
29 Sept - 30 Sept
Hotel Zaza Houston Museum District
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Daily buffet breakfast for a fee

DoubleTree by Hilton Houston Medical Center Hotel & Suites

4.0 star property
8.2 out of 10, Very good, (426)
"Great stay, shuttle to MD Anderson very convenient, they let us check out 1 hour later to accommodate Dr appt. "
The price is AU$245
includes taxes & fees
5 Oct - 6 Oct
DoubleTree by Hilton Houston Medical Center Hotel & Suites
Americas Best Value Inn Medical Center Downtown
Desk, free WiFi, bed sheets, alarm clocks

Americas Best Value Inn Medical Center Downtown

2.0 star property
8.0 out of 10, Very good, (1009)
"Clean and convenient to the medical center."
The price is AU$134
includes taxes & fees
28 Sept - 29 Sept
Americas Best Value Inn Medical Center Downtown
The Westin Houston Medical Center/Museum District
Outdoor pool, free pool cabanas, pool umbrellas

The Westin Houston Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1021)
"Great place to stay. "
The price is AU$324
includes taxes & fees
28 Sept - 29 Sept
The Westin Houston Medical Center/Museum District
Houston Marriott Medical Center/Museum District
Lobby lounge

Houston Marriott Medical Center/Museum District

4.0 star property
9.0 out of 10, Wonderful, (1010)
"Enjoyed the stay"
The price is AU$342
includes taxes & fees
11 Oct - 12 Oct
Houston Marriott Medical Center/Museum District
Wanderstay Houston Hostel
Interior

Wanderstay Houston Hostel

2.0 star property
8.4 out of 10, Very good, (184)
"This is an amazing place to stay."
The price is AU$107
includes taxes & fees
28 Sept - 29 Sept
Wanderstay Houston Hostel
Extended Stay America Suites Houston Med Ctr Braeswood Bl
Lobby

Extended Stay America Suites Houston Med Ctr Braeswood Bl

2.5 star property
6.0 out of 10, (1014)
"the place if very clean, beds are comfortable, A/C works great and quiet and the staff (Maria, Sasha) were great people. I would definitely recommend staying here again. "
The price is AU$142
includes taxes & fees
28 Sept - 29 Sept
Extended Stay America Suites Houston Med Ctr Braeswood Bl
La Maison in Midtown an urban B&B
Exterior

La Maison in Midtown an urban B&B

3.5 star property
9.8 out of 10, Exceptional, (520)
"Nice property we are enjoying our stay. "
The price is AU$314
includes taxes & fees
5 Oct - 6 Oct
La Maison in Midtown an urban B&B
Downtowner Inns - Houston Downtown
Exterior

Downtowner Inns - Houston Downtown

2.0 star property
6.8 out of 10, (3)
"Clean room"
The price is AU$170
includes taxes & fees
28 Sept - 29 Sept
Downtowner Inns - Houston Downtown
Wanderstay Boutique Hotel
Double Room, 1 Queen Bed with Sofa bed

Wanderstay Boutique Hotel

2.0 star property
9.8 out of 10, Exceptional, (47)
"The staff was amazing!! The hotel is beautiful and very clean!!"
The price is AU$209
includes taxes & fees
30 Sept - 1 Oct
Wanderstay Boutique Hotel
Hilton University of Houston
1 bedroom, premium bedding, down duvets, pillow-top beds

Hilton University of Houston

3.5 star property
8.8 out of 10, Excellent, (864)
"Overall decent property "
The price is AU$286
includes taxes & fees
25 Oct - 26 Oct
Hilton University of Houston
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Outdoor pool

Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only

3.5 star property
9.6 out of 10, Exceptional, (191)
"This was a wonderful place to stay!!"
The price is AU$333
includes taxes & fees
28 Sept - 29 Sept
Houston Towers Inn Downtown Museum District Med. Ctr NRG - Adults Only
Southmore Boulevard Motel
Standard Room, 1 King Bed

Southmore Boulevard Motel

2.0 star property
5.4 out of 10, (220)
"A classical Motel like in a Movie. The staff was really kind and helpful."
The price is AU$100
includes taxes & fees
28 Sept - 29 Sept
Southmore Boulevard Motel
Rodeway Inn & Suites Houston near Medical Center
Fridge, microwave, stovetop, coffee/tea maker

Rodeway Inn & Suites Houston near Medical Center

2.0 star property
6.2 out of 10, (491)
"Staff are rude"
The price is AU$95
includes taxes & fees
28 Sept - 29 Sept
Rodeway Inn & Suites Houston near Medical Center
Modern Cozy Home with King Bed
Comfort Townhome | Private kitchen

Modern Cozy Home with King Bed

3.5 star property
9.4 out of 10, Exceptional, (20)
"Very spacious and close to just about everything. The view is amazing too"
The price is AU$532
includes taxes & fees
29 Sept - 30 Sept
Modern Cozy Home with King Bed
Posh Dtwn Midtown Home w Stunning Roof-topterrace
House

Posh Dtwn Midtown Home w Stunning Roof-topterrace

3.0 star property
The price is AU$1,089
includes taxes & fees
28 Sept - 29 Sept
Posh Dtwn Midtown Home w Stunning Roof-topterrace
The Green Haus Luxxe Cabana Rooftop Retreat
Apartment

The Green Haus Luxxe Cabana Rooftop Retreat

2.0 star property
10.0 out of 10, Exceptional, (1)
The Green Haus Luxxe Cabana Rooftop Retreat
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
House, 3 Bedrooms | Private kitchen

Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home

3.0 star property
The price is AU$912
includes taxes & fees
28 Sept - 29 Sept
Sophisticated Urban Retreat With Skyline Views 3 Bedroom Home
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in South Central Houston

Find the best South Central Houston areas for the activities you enjoy most.
Discovery Green which includes a high-rise building, a square or plaza and a city

Downtown Houston

Tour the beautiful green spaces, buzzing theater district and professional sports arenas nestled beneath a dramatic cityscape of gleaming skyscrapers.

The Galleria

Travellers to The Galleria praise its popular shops. If you've got some more time to explore, be sure to stop by The Galleria and Williams Tower.

Texas Medical Center

Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.

Menil Collection showing interior views and art

Montrose

Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.

Houston showing a high-rise building and a city

Houston Central Business District

If you're spending time in Houston Central Business District, check out sights like Toyota Center or House of Blues Houston and hop on the metro to see more of the city at Bell Station or Main Street Square Station.

Top South Central Houston Hotel Reviews

DoubleTree by Hilton Houston Medical Center Hotel & Suites

DoubleTree by Hilton Houston Medical Center Hotel & Suites

10/10 Excellent
"Fhjgg"
Torri 2-night trip
Posted 5 days ago
DoubleTree by Hilton Houston Medical Center Hotel & Suites

Frequently asked questions

What's it like in South Central Houston?

Travellers are sure to enjoy a stay in Houston's South Central Houston neighbourhood. Looking for sights you might find in a travel guide about South Central Houston? Consider a visit to Houston Zoo while you're in the neighbourhood.

What's the best accommodation in South Central Houston?

Based on Expedia customer reviews, Wanderstay Boutique Hotel is the highest ranked property in South Central Houston. This hotel offers free parking and free WiFi. Other top choices in the neighbourhood include La Maison in Midtown an urban B&B and The Westin Houston Medical Center/Museum District.

How many hotels can I expect to find in the South Central Houston area?

Expedia has 1153 hotels and other accommodation options in South Central Houston to choose from, making this an ideal home base for exploring the greater Houston area.

If I need to cancel my hotel reservation in South Central Houston, will I receive a refund?

Yes! Most room reservations are fully refundable as long as you cancel prior to the accommodation's cancellation deadline, which often is within 24-48 hours of the scheduled arrival. If your reservation is non-refundable, you might still have the option to cancel and get a refund within a 24-hour period of your booking. Add dates, click "Search", then you can filter by "fully refundable" to view the best deals available in South Central Houston.

What is there to do around this Houston neighbourhood?

Spend some time exploring the great outdoors at Hermann Park, Cullen Sculpture Garden and Bagby Dog Park. Houston Zoo and Continental Club are some other stops worth a visit in the neighbourhood. Toyota Center and Daikin Park are some popular places to visit in the area around South Central Houston. Shape Community Center and Project Row Houses are also worth a visit when you're out sightseeing in Houston.

How can I get around South Central Houston and the greater Houston area?

For a quick way to explore the city, catch a ride on metro transit at Elgin/Third Ward Station, TSU/UH Athletics District Station or Ensemble/HCC Station.

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Explore a world of travel with Expedia