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Our top choices for Santee hotels

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (826 reviews)
"Great stay!"
United States
Preston
The price is AU$163
includes taxes & fees
27 May - 28 May
Tru By Hilton Santee

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,461 reviews)
"Great overnight stop"
United States
Gary
The price is AU$115
includes taxes & fees
18 May - 19 May
Baymont by Wyndham Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,001 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is AU$182
includes taxes & fees
21 May - 22 May
Best Western Plus Santee Inn

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,000 reviews)
"Convenient location & clean with very nice staff"
United States
Michael
The price is AU$212
includes taxes & fees
1 June - 2 June
Fairfield Inn & Suites by Marriott Santee

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (731 reviews)
"Staff was very friendly. "
United States
Sriram
The price is AU$96
includes taxes & fees
21 May - 22 May
Travelodge by Wyndham Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,000 reviews)
"Really nice breakfast. "
United States
Susan
The price is AU$174
includes taxes & fees
31 May - 1 June
Comfort Inn & Suites Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,000 reviews)
"Great stay!"
United States
Preston
The price is AU$183
includes taxes & fees
7 June - 8 June
Hampton Inn Santee-I-95

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,001 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
The price is AU$179
includes taxes & fees
24 May - 25 May
Holiday Inn Santee by IHG

Super 8 by Wyndham Santee

Super 8 by Wyndham Santee
2.0 star property
Santee
6.8 out of 10, (460 reviews)
"Clean & comfortable room"
United States
Darrell
The price is AU$97
includes taxes & fees
26 May - 27 May
Super 8 by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (529 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is AU$91
includes taxes & fees
7 June - 8 June
Quality Inn & Suites Santee I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (654 reviews)
"The check in lady was uncooperative & unhelpful. Only 1 towel for each person. Would not recommend. "
United States
Dave
The price is AU$96
includes taxes & fees
19 May - 20 May
Red Roof Inn Santee

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (558 reviews)
"Clean room and good staff"
United States
Herbert
The price is AU$113
includes taxes & fees
7 June - 8 June
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
"Very clean room, fast staff, a lot of food spots nearby! "
United States
Santiana
The price is AU$116
includes taxes & fees
28 May - 29 May
Econo Lodge Santee

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.4 out of 10, Good, (206 reviews)
"Was very clean and confortable "
United States
David
The price is AU$89
includes taxes & fees
24 May - 25 May
Peach Tree Inn

Southern Lodge 601

Southern Lodge 601
Orangeburg
7.2 out of 10, Good, (7 reviews)
"The front desk and housekeeping staff were friendly and accommodating. The room was clean and comfortable but had a little "stale" odor but I became accustomed to it quickly. I felt safe in my room, and the neighbors were very quiet. Will stay here again, great bargain and convenient to I-26!"
United States
Stephanie
The price is AU$109
includes taxes & fees
1 June - 2 June
Southern Lodge 601

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (766 reviews)
"Great stay!!"
United States
Laylany
The price is AU$168
includes taxes & fees
19 May - 20 May
Fairfield Inn by Marriott Orangeburg

Travelodge by Wyndham Orangeburg

Travelodge by Wyndham Orangeburg
2.0 star property
Orangeburg
8.2 out of 10, Very good, (1,003 reviews)
"Clean rooms, great staff, easy parking"
United States
Leslie
The price is AU$121
includes taxes & fees
24 May - 25 May
Travelodge by Wyndham Orangeburg

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,001 reviews)
"Excellent place to stay"
United States
Bartolo
The price is AU$175
includes taxes & fees
28 May - 29 May
Tru by Hilton Orangeburg

Red Roof Inn St George, SC

Red Roof Inn St George, SC
2.5 star property
St. George
7.4 out of 10, Good, (677 reviews)
"Pleasant staff, room was clean"
United States
Debi
The price is AU$115
includes taxes & fees
27 May - 28 May
Red Roof Inn St George, SC

SureStay Hotel by Best Western Manning

SureStay Hotel by Best Western Manning
2.5 star property
Manning
8.6 out of 10, Excellent, (1,000 reviews)
"Great location. Good breakfast"
United States
kenneth
The price is AU$152
includes taxes & fees
24 May - 25 May
SureStay Hotel by Best Western Manning
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap accommodation in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Based on our traveller data, Baymont by Wyndham Santee is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your visit include Tru By Hilton Santee and Hampton Inn Santee-I-95. See all available top hotels, or vacation rentals in Santee.
What are some of the best holiday rentals that Santee has to offer?
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated holiday home rental in Santee is located on a lake, and has a patio, a selection of games and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Comfort Inn & Suites Santee is a hotel with free parking and free buffet breakfast, and it's a top choice on Expedia for families. Fairfield Inn & Suites by Marriott Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Baymont by Wyndham Santee is a top hotel for people travelling with their pets, and offers concierge services and free WiFi for its human guests. Two other good options for you and your pet include Tru By Hilton Santee and Best Western Plus Santee Inn. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Super 8 by Wyndham Santee and Ramada by Wyndham Santee I-95. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 128 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee State Park and Lake Marion. A couple of additional sights to add to your itinerary are Santee National Golf Club and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

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