
Search Saint Matthews hotels
- Change your mindBook hotels with free cancellation
- Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Saint Matthews
Family friendly
Cabin
Check prices for these dates
Our top choices for Saint Matthews hotels

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,446 reviews)
The price is AU$116
includes taxes & fees
23 Apr - 24 Apr

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (798 reviews)
The price is AU$178
includes taxes & fees
10 May - 11 May

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (751 reviews)
The price is AU$130
includes taxes & fees
19 May - 20 May

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,002 reviews)
The price is AU$207
includes taxes & fees
4 May - 5 May

Southern Lodge 601
Southern Lodge 601Orangeburg
7.6 out of 10, Good, (4 reviews)
The price is AU$111
includes taxes & fees
30 Apr - 1 May

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,006 reviews)
The price is AU$214
includes taxes & fees
10 May - 11 May

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,001 reviews)
The price is AU$184
includes taxes & fees
3 May - 4 May

Travelodge by Wyndham Orangeburg
Travelodge by Wyndham OrangeburgOrangeburg
8.2 out of 10, Very good, (1,008 reviews)
The price is AU$110
includes taxes & fees
23 Apr - 24 Apr

Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,006 reviews)
The price is AU$179
includes taxes & fees
19 May - 20 May

La Quinta Inn by Wyndham Columbia SE / Fort Jackson
La Quinta Inn by Wyndham Columbia SE / Fort JacksonColumbia
8.0 out of 10, Very good, (1,010 reviews)
The price is AU$145
includes taxes & fees
3 May - 4 May

Springhill Suites by Marriott Columbia near Fort Jackson
Springhill Suites by Marriott Columbia near Fort JacksonColumbia
9.4 out of 10, Exceptional, (669 reviews)
The price is AU$171
includes taxes & fees
3 May - 4 May

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,005 reviews)
The price is AU$176
includes taxes & fees
19 May - 20 May

Courtyard by Marriott Columbia Cayce
Courtyard by Marriott Columbia CayceCayce
9.0 out of 10, Wonderful, (695 reviews)
The price is AU$183
includes taxes & fees
17 May - 18 May

Spark by Hilton Orangeburg
Spark by Hilton OrangeburgOrangeburg
7.8 out of 10, Good, (1,002 reviews)
The price is AU$159
includes taxes & fees
26 Apr - 27 Apr

Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (512 reviews)
The price is AU$92
includes taxes & fees
3 May - 4 May

Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (799 reviews)
The price is AU$202
includes taxes & fees
10 May - 11 May

SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott OrangeburgOrangeburg
8.8 out of 10, Excellent, (739 reviews)
The price is AU$203
includes taxes & fees
4 May - 5 May

Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.2 out of 10, Good, (721 reviews)
The price is AU$97
includes taxes & fees
26 Apr - 27 Apr

Super 8 by Wyndham Santee
Super 8 by Wyndham SanteeSantee
6.8 out of 10, (454 reviews)
The price is AU$116
includes taxes & fees
23 Apr - 24 Apr

Econo Lodge Inn & Suites Cayce I-26 Airport
Econo Lodge Inn & Suites Cayce I-26 AirportCayce
7.6 out of 10, Good, (31 reviews)
The price is AU$110
includes taxes & fees
21 May - 22 May
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Learn more about Saint Matthews
Discover small-town charm at the Calhoun County Museum, where local history comes alive through fascinating exhibits. Enjoy peaceful picnics at the town park or visit nearby Congaree National Park for remarkable hiking trails through ancient bottomland hardwood forest.

Top Saint Matthews Hotel Reviews
Recent Reviews in Saint Matthews

Cambria Hotel Columbia Downtown The Vista
10/10 Excellent
More cheap accommodation in Saint Matthews

Motel 6 West Columbia, SC - Airport
650 Cherokee Lane West Columbia SC
The price is AU$101 per night from 23 Apr to 24 Apr
AU$101
23 Apr - 24 Apr
includes taxes & fees
7.6/10 Good! (559 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- B&B in Bowman
- Farmstay in Bowman
- Bowman Hotels
- Brookdale Hotels
- Caravan Parks in Cameron
- Luxury Hotels in Cameron
- Cayce Hotels
- Cherryvale Hotels
- Hotels near Columbia Metropolitan Convention Center
- Hotels near Congaree National Park
- Holiday Homes in Cope
- All Inclusive Hotels in South Carolina
- Beach Hotels in South Carolina
- Casino Hotels in South Carolina
- Cheap Hotels in South Carolina
- Green Hotels in South Carolina
- Luxury Hotels in South Carolina
- Pet Friendly Hotels in South Carolina
- Romantic Hotels in South Carolina
- Eastover Hotels
- Elloree Hotels
- Caravan Parks in Forest Acres
- Hotels near Fort Jackson
- Gadsden Hotels
- Gaston Hotels
- Caravan Parks in Hopkins
- Hopkins Hotels
- Motels in Hopkins
- Caravan Parks in Neeses
- Neeses Hotels
- Caravan Parks in North
- North Hotels
- Oakland Hotels
- Orangeburg Hotels
- B&B in Pinewood
- Caravan Parks in Pinewood
- Pinewood Hotels
- Cheap Hotels in Rosewood
- Hotels with Pool in Rosewood
- Luxury Hotels in Rosewood
- Spa Hotels in Rosewood
- Rosewood Hotels
- Santee Hotels
- Hotels near Santee State Park
- Shandon Hotels
- Hotels near Shaw Air Force Base
- Apartments in South Carolina
- B&B in South Carolina
- Cabin Rentals in South Carolina
- Caravan Parks in South Carolina
- Condo Rentals in South Carolina
- Cottages in South Carolina
- Farmstay in South Carolina
- Guest Houses in South Carolina
- Inns in South Carolina
- Lodges in South Carolina
- Motels in South Carolina
- Resort in South Carolina
- Serviced Apartments in South Carolina
- Hotels near South Carolina State Fairgrounds
- Villas in South Carolina
- Lgbt Welcoming Hotels in Stilton
- Stilton Hotels
- Hotels with Parking in Summerton
- Summerton Hotels
- B&B in Swansea
- Caravan Parks in Swansea
- Holiday Homes in Swansea
- Luxury Hotels in Swansea
- Swansea Hotels
- Hotels near University of South Carolina
- Vance Hotels
- Wateree Hotels
- Hotels near Williams Brice Stadium









































































