Santee Holiday Rentals

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Holiday Rentals in Santee

Holiday Home in Santee

4.0 star property
9.2 out of 10, Wonderful, (20)
"Beautiful resort with quiet and peaceful surroundings "
United States
kizie
Wyndham Vacation Resorts Lake Marion

Holiday Home in Santee

10.0 out of 10, Exceptional, (37)
"Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! "
United States
Lauren B.
The price is AU$500
includes taxes & fees
8 Dec - 9 Dec
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Condo in Santee

10.0 out of 10, Exceptional, (9)
"Very very nice. Would recommend it for a great stay. "
United States
susan l.
Lake Marion - Majestic Big Water View!

Condo in Santee

10.0 out of 10, Exceptional, (6)
"Fantastic location on the lake and access to the pool as well. Home was clean and had everything we needed for our stay. Amazing communication with the owner. Will stay again."
United States
Erin B.
Charming 2 Bedroom Waterfront Lake Marion Condo

Condo in Santee

9.4 out of 10, Exceptional, (14)
"Great place to stay. "
United States
James
Sunsets on Lake Marion

Cottage in Elloree

8.4 out of 10, Very good, (6)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
The price is AU$337
includes taxes & fees
1 Jan - 2 Jan 2026
Tranquil Studio Cottage with Heated Pool and Fishing Access

Condo in Santee

Beautiful, ground level 3-bedroom condo with pool on scenic Lake Marion

Condo in Santee

9.6 out of 10, Exceptional, (9)
"I had a very nice time and I will definitely come back here"
United States
Anna
Lakeside vacationing close to golf courses, restaurants and boat rental company!

Holiday Home in Santee

Lakeside Charming 2-bedroom house in lovely Santee with AC, WiFi

Condo in Santee

10.0 out of 10, Exceptional, (11)
"Nice place great location "
United States
Jeffrey H.
The price is AU$718
includes taxes & fees
16 Dec - 17 Dec
Peaceful Condo on Lake Marion in Santee, SC. Time to play golf and go fishing!

Cottage in Santee

3.0 star property
Elloree Vacation Rental ~ 7 Mi to Lake Marion!

Aparthotel in Eutawville

2.5 star property
8.6 out of 10, Excellent, (78)
"Room was clean with a beautiful view of the Lake."
United States
Melanie
Bells Marina & Resort

Cabin in Summerton

2.0 star property
9.6 out of 10, Exceptional, (15)
"Convenient location, enjoyed fishing from dock in front too. Just right for quick fishing trip."
United States
Chris R.
The price is AU$251
includes taxes & fees
15 Dec - 16 Dec
Lakefront tiny cabin amazing view on Lake Marion! Pet friendly & sleeps 6

Holiday Home in Elloree

10.0 out of 10, Exceptional, (74)
"I would stay here again. Great location."
United States
John M.
Lake Marion Lakehouse with 180° lake view

Cottage in Holly Hill

10.0 out of 10, Exceptional, (122)
"Perfect, quiet spot for relaxing with your family and fur babies. This little house had everything we needed!"
United States
Darlyn H.
The price is AU$315
includes taxes & fees
8 Dec - 9 Dec
Pet friendly country cottage with large fenced-in yard & horses on property

Holiday Home in Summerton

9.6 out of 10, Exceptional, (243)
"Great place. Had a blast. "
United States
Kim L.
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable

Mobile Home in Elloree

9.4 out of 10, Exceptional, (21)
"Great place for our family to stop on our way to Florida. It had ample parking, pet friendly, and very comfortable country retreat! "
United States
Jackie M.
The price is AU$275
includes taxes & fees
4 Jan - 5 Jan 2026
Country Resting Spot just off I95. 12 miles west on hwy 6.

Holiday Home in Summerton

10.0 out of 10, Exceptional, (161)
"Always enjoy our stay"
United States
Tabitha K.
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS

Holiday Home in Summerton

9.0 out of 10, Wonderful, (59)
"The entire home was spotless "
United States
Paola
Beautiful lake home to make your family vacation extra special!

Cabin in Rimini

8.2 out of 10, Very good, (14)
"Wish bathroom was closer but jt"
United States
Sharon W.
The price is AU$204
includes taxes & fees
6 Dec - 7 Dec
Cozy Camping Cabin on Lake Marion near Congaree Nat Park
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Santee Hotel Reviews

Find out more about Santee

Everything you need to know about Santee holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Santee holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Santee holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Santee holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Santee. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Santee holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Santee holiday rentals we have selected for you start as low as AU$204 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Santee rentals

At Expedia, we put the best Santee holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Santee rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Santee holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Santee. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence. 

Frequently asked questions

Can I find holiday rentals in Santee?

Yes, there are holiday rentals close to the most popular sights in Santee, or you can select a more secluded option if you're looking for a relaxing stay. Tourists appreciate the top-notch restaurants and coffee shops in Santee. Make sure you have time to check out the golf courses and lake views during your trip.

What are some of the best holiday rentals that Santee has to offer?

Wyndham Vacation Resorts Lake Marion: This highly rated holiday home rental in Santee is equipped with an outdoor pool, free WiFi and cable TV to help you feel comfortable during your stay. Kitchen amenities include a full-sized fridge, a dishwasher and a stovetop. Another good choice for your trip to Santee is Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!.

How many holiday rentals are there in Santee?

Expedia has 9 holiday rentals for your stay in Santee.

What can I see and do in Santee?

While you're exploring the area, Lake Marion and Taw Caw Creek are a couple of picturesque spots to get outside and enjoy nature. Santee Cooper Country Club and Santee National Golf Club are other places to visit while you're in town.

What are holiday rentals like in Santee?

Holiday rentals are privately owned properties you can book for a few days, or a quick weekend, in Santee. Holiday rentals feature amenities like kitchens and laundry facilities so your stay will be comfortable. If you're concerned about a sanitised environment, holiday rentals can provide a sense of security away from public hotel lifts and busy reception areas while still allowing you the enjoyment of travel. You'll also have more space in a holiday rental than in a standard hotel, which is another reason why a holiday rental is a great option for small groups.