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Our top choices for Santee hotels

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,006 reviews)
"Nice hotel stay, excellent staff and accommodations."
United States
Carl
The price is AU$209
includes taxes & fees
22 June - 23 June
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,003 reviews)
"Great place to stay!!! Friendly staff and easy access to a great restaurant across the street. Wr will definitely be staying here again."
United States
Sandra
The price is AU$201
includes taxes & fees
28 June - 29 June
Hampton Inn Santee-I-95

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (843 reviews)
"The older man that worked upfront at the time of my check in was super nice and helpful!"
United States
Kristal
The price is AU$167
includes taxes & fees
22 June - 23 June
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,003 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is AU$173
includes taxes & fees
21 June - 22 June
Best Western Plus Santee Inn

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,470 reviews)
"Great overnight stop"
United States
Gary
The price is AU$126
includes taxes & fees
7 June - 8 June
Baymont by Wyndham Santee

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,009 reviews)
"This property is right off the interstate with no traffic. The staff was very friendly and the hotel was clean. Breakfast and coffee were delicious. Highly recommend "
United States
Kimberley
The price is AU$163
includes taxes & fees
14 June - 15 June
Comfort Inn & Suites Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,002 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
The price is AU$156
includes taxes & fees
14 June - 15 June
Holiday Inn Santee by IHG

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (737 reviews)
"Staff was very friendly. "
United States
Sriram
The price is AU$98
includes taxes & fees
17 June - 18 June
Travelodge by Wyndham Santee

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (465 reviews)
"Ok hotel when money is tight. Only stayed one night but the room was clean and the beds were pretty comfy."
United States
Christalyn
The price is AU$99
includes taxes & fees
14 June - 15 June
Super 8 by Wyndham Santee/I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (655 reviews)
"Yes, great room."
United States
Gerald
The price is AU$98
includes taxes & fees
9 June - 10 June
Red Roof Inn Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (538 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is AU$95
includes taxes & fees
30 June - 1 July
Quality Inn & Suites Santee I-95

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (563 reviews)
"The room was very clean, the staff very friendly, and the restaurant/bar had good food and drinks and the pool tables added a unique touch!"
United States
Phyllis
The price is AU$115
includes taxes & fees
22 June - 23 June
Ramada by Wyndham Santee I-95

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
"Very clean room, fast staff, a lot of food spots nearby! "
United States
Santiana
The price is AU$100
includes taxes & fees
5 July - 6 July
Econo Lodge Santee

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (782 reviews)
"Great stay!!"
United States
Laylany
The price is AU$183
includes taxes & fees
8 June - 9 June
Fairfield Inn by Marriott Orangeburg

Sunset Inn Manning I 95

Sunset Inn Manning I 95
2.0 star property
Summerton
4.8 out of 10, (55 reviews)
"Ok good value"
United States
William
The price is AU$79
includes taxes & fees
7 June - 8 June
Sunset Inn Manning I 95

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (805 reviews)
"The stay was great."
United States
Brandon
The price is AU$205
includes taxes & fees
5 July - 6 July
Hampton Inn & Suites Orangeburg

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (763 reviews)
"Very nice hotel"
United States
Theresa
The price is AU$177
includes taxes & fees
28 June - 29 June
SpringHill Suites by Marriott Orangeburg

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent place to stay"
United States
Bartolo
The price is AU$177
includes taxes & fees
1 July - 2 July
Tru by Hilton Orangeburg

Doyles B and B at Players course LLC

Doyles B and B at Players course LLC
3.5 star property
Manning
The price is AU$278
includes taxes & fees
7 June - 8 June
Doyles B and B at Players course LLC

Peach Tree Inn

Peach Tree Inn
2.5 star property
St. George
7.2 out of 10, Good, (219 reviews)
"Your usually 2-3 star rating lodge place."
United States
David
The price is AU$93
includes taxes & fees
10 June - 11 June
Peach Tree Inn
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap accommodation in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Based on our traveller data, Baymont by Wyndham Santee is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your visit include Tru By Hilton Santee and Comfort Inn & Suites Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best holiday rentals that Santee has to offer?
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated holiday home rental in Santee is located on a lake, and has a patio, a selection of games and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Another good choice for your trip to Santee is Patio + Pool Table: Lake Marion Getaway. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Baymont by Wyndham Santee is a top hotel for people travelling with their pets, and offers concierge services and free WiFi for its human guests. Two other good options for you and your pet include Best Western Plus Santee Inn and Tru By Hilton Santee. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Super 8 by Wyndham Santee and Ramada by Wyndham Santee I-95. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 129 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee National Golf Club and Santee State Park. A couple of additional sights to add to your itinerary are Lake Marion and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

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