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Our top choices for Santee hotels

Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (750 reviews)
The price is AU$177
includes taxes & fees
16 Mar - 17 Mar

Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,444 reviews)
The price is AU$126
includes taxes & fees
9 Mar - 10 Mar

Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,005 reviews)
The price is AU$199
includes taxes & fees
25 Mar - 26 Mar

Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,012 reviews)
The price is AU$197
includes taxes & fees
17 Mar - 18 Mar

Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,008 reviews)
The price is AU$164
includes taxes & fees
15 Mar - 16 Mar

Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (1,002 reviews)
The price is AU$201
includes taxes & fees
15 Mar - 16 Mar

Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
6.4 out of 10, (552 reviews)
The price is AU$128
includes taxes & fees
15 Mar - 16 Mar

Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.0 out of 10, Good, (703 reviews)
The price is AU$99
includes taxes & fees
9 Mar - 10 Mar

Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,008 reviews)
The price is AU$177
includes taxes & fees
9 Mar - 10 Mar

Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (478 reviews)
The price is AU$94
includes taxes & fees
15 Mar - 16 Mar

Super 8 by Wyndham Santee
Super 8 by Wyndham SanteeSantee
6.8 out of 10, (444 reviews)
The price is AU$118
includes taxes & fees
9 Mar - 10 Mar

Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (311 reviews)
The price is AU$108
includes taxes & fees
25 Mar - 26 Mar

Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (646 reviews)
The price is AU$92
includes taxes & fees
15 Mar - 16 Mar

Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,003 reviews)
The price is AU$180
includes taxes & fees
24 Mar - 25 Mar

Spark by Hilton Orangeburg
Spark by Hilton OrangeburgOrangeburg
7.8 out of 10, Good, (1,007 reviews)
The price is AU$163
includes taxes & fees
12 Mar - 13 Mar

Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (735 reviews)
The price is AU$146
includes taxes & fees
9 Mar - 10 Mar

Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (789 reviews)
The price is AU$206
includes taxes & fees
22 Mar - 23 Mar

SureStay Hotel by Best Western Manning
SureStay Hotel by Best Western ManningManning
8.6 out of 10, Excellent, (1,003 reviews)
The price is AU$141
includes taxes & fees
15 Mar - 16 Mar
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions
Learn more about Santee
Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Top Santee Hotel Reviews
Recent Reviews in Santee

SpringHill Suites by Marriott Orangeburg
8/10 Good
More cheap accommodation in Santee

Travelodge by Wyndham Orangeburg
3620 Saint Matthews Rd Orangeburg SC
The price is AU$118 per night from 9 Mar to 10 Mar
AU$118
9 Mar - 10 Mar
includes taxes & fees
8.2/10 Very Good! (1,005 reviews)
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