Search Santee hotels
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Go beyond your typical stay in Santee
Cabin
Pet friendly
Check prices for these dates
Tonight
Tomorrow
Next weekend
In two weeks
Our top choices for Santee hotels
Fairfield Inn & Suites by Marriott Santee
Fairfield Inn & Suites by Marriott SanteeSantee
9.8 out of 10, Exceptional, (1,006 reviews)
"Nice hotel stay, excellent staff and accommodations."
Carl
The price is AU$209
includes taxes & fees
22 June - 23 June
Hampton Inn Santee-I-95
Hampton Inn Santee-I-95Santee
9.6 out of 10, Exceptional, (1,003 reviews)
"Great place to stay!!! Friendly staff and easy access to a great restaurant across the street. Wr will definitely be staying here again."
Sandra
The price is AU$201
includes taxes & fees
28 June - 29 June
Tru By Hilton Santee
Tru By Hilton SanteeSantee
9.2 out of 10, Wonderful, (843 reviews)
"The older man that worked upfront at the time of my check in was super nice and helpful!"
Kristal
The price is AU$167
includes taxes & fees
22 June - 23 June
Best Western Plus Santee Inn
Best Western Plus Santee InnSantee
8.8 out of 10, Excellent, (1,003 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
Nicole
The price is AU$173
includes taxes & fees
21 June - 22 June
Baymont by Wyndham Santee
Baymont by Wyndham SanteeSantee
8.0 out of 10, Very good, (1,470 reviews)
"Great overnight stop"
Gary
The price is AU$126
includes taxes & fees
7 June - 8 June
Comfort Inn & Suites Santee
Comfort Inn & Suites SanteeSantee
8.0 out of 10, Very good, (1,009 reviews)
"This property is right off the interstate with no traffic. The staff was very friendly and the hotel was clean. Breakfast and coffee were delicious. Highly recommend "
Kimberley
The price is AU$163
includes taxes & fees
14 June - 15 June
Holiday Inn Santee by IHG
Holiday Inn Santee by IHGSantee
8.2 out of 10, Very good, (1,002 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
Stefanie
The price is AU$156
includes taxes & fees
14 June - 15 June
Travelodge by Wyndham Santee
Travelodge by Wyndham SanteeSantee
7.2 out of 10, Good, (737 reviews)
"Staff was very friendly. "
Sriram
The price is AU$98
includes taxes & fees
17 June - 18 June
Super 8 by Wyndham Santee/I-95
Super 8 by Wyndham Santee/I-95Santee
6.8 out of 10, (465 reviews)
"Ok hotel when money is tight. Only stayed one night but the room was clean and the beds were pretty comfy."
Christalyn
The price is AU$99
includes taxes & fees
14 June - 15 June
Red Roof Inn Santee
Red Roof Inn SanteeSantee
6.6 out of 10, (655 reviews)
"Yes, great room."
Gerald
The price is AU$98
includes taxes & fees
9 June - 10 June
Quality Inn & Suites Santee I-95
Quality Inn & Suites Santee I-95Santee
6.0 out of 10, (538 reviews)
"Rooms are clean and staff was super nice and accommodating "
Will
The price is AU$95
includes taxes & fees
30 June - 1 July
Ramada by Wyndham Santee I-95
Ramada by Wyndham Santee I-95Santee
6.4 out of 10, (563 reviews)
"The room was very clean, the staff very friendly, and the restaurant/bar had good food and drinks and the pool tables added a unique touch!"
Phyllis
The price is AU$115
includes taxes & fees
22 June - 23 June
Econo Lodge Santee
Econo Lodge SanteeSantee
6.4 out of 10, (314 reviews)
"Very clean room, fast staff, a lot of food spots nearby! "
Santiana
The price is AU$100
includes taxes & fees
5 July - 6 July
Fairfield Inn by Marriott Orangeburg
Fairfield Inn by Marriott OrangeburgOrangeburg
8.4 out of 10, Very good, (782 reviews)
"Great stay!!"
Laylany
The price is AU$181
includes taxes & fees
23 June - 24 June
Sunset Inn Manning I 95
Sunset Inn Manning I 95Summerton
4.8 out of 10, (55 reviews)
"Ok good value"
William
The price is AU$79
includes taxes & fees
7 June - 8 June
Hampton Inn & Suites Orangeburg
Hampton Inn & Suites OrangeburgOrangeburg
9.4 out of 10, Exceptional, (805 reviews)
"The stay was great."
Brandon
The price is AU$205
includes taxes & fees
5 July - 6 July
SpringHill Suites by Marriott Orangeburg
SpringHill Suites by Marriott OrangeburgOrangeburg
8.8 out of 10, Excellent, (763 reviews)
"Very nice hotel"
Theresa
The price is AU$177
includes taxes & fees
28 June - 29 June
Tru by Hilton Orangeburg
Tru by Hilton OrangeburgOrangeburg
9.2 out of 10, Wonderful, (1,004 reviews)
"Excellent place to stay"
Bartolo
The price is AU$177
includes taxes & fees
1 July - 2 July
Doyles B and B at Players course LLC
Doyles B and B at Players course LLCManning
The price is AU$278
includes taxes & fees
7 June - 8 June
Peach Tree Inn
Peach Tree InnSt. George
7.2 out of 10, Good, (219 reviews)
"Your usually 2-3 star rating lodge place."
David
The price is AU$93
includes taxes & fees
10 June - 11 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Stay near popular Santee attractions
Learn more about Santee
Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.
More cheap accommodation in Santee
Peach Tree Inn
111 Conners Dr St. George SC
The price is AU$93 per night from 10 June to 11 June
AU$93
10 June - 11 June
includes taxes & fees
7.2/10 Good! (219 reviews)
Frequently asked questions
Explore a world of travel with Expedia
- Alcolu Hotels
- Cheap Hotels in Bamberg
- Luxury Hotels in Bamberg
- Marriott Hotels & Resorts in Bamberg
- Bonneau Hotels
- B&B in Bowman
- Farmstay in Bowman
- Bowman Hotels
- Brookdale Hotels
- Caravan Parks in Cameron
- Luxury Hotels in Cameron
- Holiday Homes in Canadys
- Canadys Hotels
- Cherryvale Hotels
- Hotels near Congaree National Park
- Holiday Homes in Cope
- Cheap Hotels in Cross
- Cross Hotels
- Davis Station Hotels
- Eastover Hotels
- Elloree Hotels
- Gable Hotels
- Gadsden Hotels
- Harleyville Hotels
- B&B in Manning
- Cheap Hotels in Manning
- Hotels with Parking in Manning
- Manning Hotels
- Motels in Manning
- Spa Hotels in Moncks Corner
- Moncks Corner Hotels
- Mulberry Hotels
- Orangeburg Hotels
- B&B in Pinewood
- Caravan Parks in Pinewood
- Pinewood Hotels
- Pinopolis Hotels
- Saint Matthews Hotels
- Motels in Saint Matthews
- Hotels near Santee State Park
- B&B in St. George
- Caravan Parks in St. George
- Holiday Homes in St. George
- Boutique Hotels in St. George
- Business Hotels in St. George
- Cheap Hotels in St. George
- Hotels with Parking in St. George
- Pet Friendly Hotels in St. George
- St. George Hotels
- Resort in St. George
- Condo Rentals in St. Stephen
- St. Stephen Hotels
- Lgbt Welcoming Hotels in Stilton
- Stilton Hotels
- Hotels with Parking in Summerton
- Summerton Hotels
- Cabin Rentals in Summerville
- Hotels with Parking in Sumter
- Sumter Hotels
- Vance Hotels
- Wateree Hotels
- Whitesville Hotels
- Flights to Bamberg
- Flights to Cameron
- Flights to Cherry Hill
- Flights to Cordova
- Flights to Cross
- Flights to Davis Station
- Flights to Manning
- Flights to Moncks Corner
- Flights to Oakland
- Flights to Providence
- Flights to South Sumter
- Flights to St. George
- Flights from Shaw Air Force Base
- Flights from Alcolu
- Flights from Davis Station
- Flights from Orangeburg
- Flights from Dallas (DFW) to Sumter (SUM)
- Airport Van Rental Rental Cars in Lake Marion
- Alamo Rent A Car Rental Cars in Lake Marion
- Apex Car Rentals Rental Cars in Lake Marion
- Car hire Manning
- Car hire Oakland
- Car hire St. George
- Car hire near Sumter Mall
- Rental cars Sumter Municipal airport
- Europcar Rental Cars in Privateer
- Priceless Car Rental Rental Cars in Lake Marion
- Standard Car Hire in Lake Marion
