Family Hotels & Resorts in Santee from AU$102

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on Santee Family Hotels

Tonight
7 Dec - 8 Dec
Tomorrow
8 Dec - 9 Dec
Next weekend
12 Dec - 14 Dec
In two weeks
19 Dec - 21 Dec

Best Santee Family Hotels

Property amenity
Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee

2.5 star property
Santee
9.8 out of 10, Exceptional, (1002)
"Clean, friendly staff, new, good value"
United States
Robert
The price is AU$202
includes taxes & fees
14 Dec - 15 Dec
Fairfield Inn & Suites by Marriott Santee
Seasonal outdoor pool
Comfort Inn & Suites Santee

Comfort Inn & Suites Santee

2.5 star property
Santee
8.0 out of 10, Very good, (1002)
"Close to the highway with a safe location."
United States
Benjamin
The price is AU$165
includes taxes & fees
14 Dec - 15 Dec
Comfort Inn & Suites Santee
Exterior
Best Western Plus Santee Inn

Best Western Plus Santee Inn

2.5 star property
Santee
8.8 out of 10, Excellent, (1001)
"Nice rooms and very good breakfast items."
United States
Stephen
The price is AU$197
includes taxes & fees
14 Dec - 15 Dec
Best Western Plus Santee Inn
Exterior
Travelodge by Wyndham Santee

Travelodge by Wyndham Santee

2.0 star property
Santee
7.0 out of 10, Good, (675)
"The room was very nice. It was newly renovated and I loved the upgrade. The beds were comfortable and warm. We didn’t eat breakfast because we were meeting someone for breakfast. "
United States
Alice
The price is AU$102
includes taxes & fees
5 Jan - 6 Jan 2026
Travelodge by Wyndham Santee
Interior
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!

Santee
10.0 out of 10, Exceptional, (37)
"Amazing host, comfy furniture, the fenced in yard was perfect for our fur babies! Hope to stay here again. 1.2 miles away from I-95! "
United States
Lauren B.
The price is AU$487
includes taxes & fees
9 Dec - 10 Dec
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Outdoor pool, a heated pool
Tranquil Studio Cottage with Heated Pool and Fishing Access

Tranquil Studio Cottage with Heated Pool and Fishing Access

Elloree
8.4 out of 10, Very good, (6)
"Great property the pool was so fun! Mostly stayed on the property and lounged around for a nice relaxing stay!"
United States
Tori P.
The price is AU$336
includes taxes & fees
1 Jan - 2 Jan 2026
Tranquil Studio Cottage with Heated Pool and Fishing Access
Exterior
Econo Lodge

Econo Lodge

2.0 star property
Santee
6.4 out of 10, (309)
"Check in was easy."
United States
Amy
The price is AU$106
includes taxes & fees
22 Dec - 23 Dec
Econo Lodge
Standard Room, 2 Queen Beds, Non Smoking
Peach Tree Inn

Peach Tree Inn

2.5 star property
St. George
7.2 out of 10, Good, (134)
"Air conditioning very good, check in easy, staff very pleasant"
United States
Linda
Peach Tree Inn
Desk, iron/ironing board, free cots/infant beds, free WiFi
Comfort Inn & Suites Orangeburg

Comfort Inn & Suites Orangeburg

2.5 star property
Orangeburg
8.0 out of 10, Very good, (545)
"Would recommend this hotel for out of town guest with no hesitation. "
United States
Yvette
The price is AU$158
includes taxes & fees
21 Dec - 22 Dec
Comfort Inn & Suites Orangeburg
Lobby
Sleep Inn Orangeburg

Sleep Inn Orangeburg

2.5 star property
Orangeburg
7.6 out of 10, Good, (381)
"Courteous staff"
United States
David
The price is AU$125
includes taxes & fees
27 Dec - 28 Dec
Sleep Inn Orangeburg
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Top Santee Hotel Reviews

Baymont by Wyndham Santee

Baymont by Wyndham Santee

10/10 Excellent
"Great staff"
Rubin 2-night trip
Posted 8 days ago
Baymont by Wyndham Santee

Frequently asked questions

What's Santee like for family-friendly holidays?
The welcoming destination of Santee is a great choice if you've been thinking about a holiday with the children. The excursions, lake views and golf are just a few things that make this an attractive holiday destination for families. Arrange a flight into Columbia, SC (CAE-Columbia Metropolitan), which is located 49 mi (78.8 km) from the city centre.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your family trip.
When's the best time to book a family-friendly holiday in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.
What's there to see and do with your family in Santee?
While you and your family are visiting Santee, you may want to explore some child-friendly attractions such as Santee Indian Mound and Fort Watson Site and Orangeburg County Library Mentor Branch. Make sure that you have lots of time for activities such as Lake Marion and Taw Caw Creek.