Medellin, Antioquia - Colombia. February 13, 2026. Catholic parish located in the La America neighborhood

Santa Fe Hotels, Medellín

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Our top choices for Santa Fe hotels

1. HOTEL CASA MEGUA3

HOTEL CASA MEGUA3
2.0 star property
Santa Fe
The price is AU$60
10 Sept - 11 Sept
HOTEL CASA MEGUA3

2. Ayenda Casa San Pablo

Ayenda Casa San Pablo
2.5 star property
Santa Fe
8.0 out of 10, Very good, (7 reviews)
"Room was very small, the bathroom tiny and uncomfortable to navigate. Facilities were clean and the staff courteous."
United States
Jose
Ayenda Casa San Pablo

3. Hotel boutique Olaya 54

Hotel boutique Olaya 54
2.0 star property
Santa Fe
The price is AU$113
11 Aug - 12 Aug
Hotel boutique Olaya 54

4. ibis Medellin

ibis Medellin
3.0 star property
0.8 km from Santa Fe
8.8 out of 10, Excellent, (1,002 reviews)
"Great location, helpful staff, near some Landmarks of the city"
United States
Javier
The price is AU$86
29 Aug - 30 Aug
ibis Medellin

5. V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
3.5 star property
Castropol, 1.6 km from Santa Fe
9.2 out of 10, Wonderful, (1,383 reviews)
"This place is great! I’m definitely staying here next time I visit Medellín. Breakfast was great too."
United States
James
The price is AU$144
30 Aug - 31 Aug
V Grand Hotel, a member of Radisson Individuals

6. Heiss Hotel By Jalo

Heiss Hotel By Jalo
4.0 star property
El Poblado, 1.3 km from Santa Fe
9.2 out of 10, Wonderful, (1,738 reviews)
"Great stay, second time we have stayed here"
United States
Kathya
The price is AU$104
7 Sept - 8 Sept
Heiss Hotel By Jalo

7. Landmark Hotel

Landmark Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.6 out of 10, Exceptional, (443 reviews)
"Very clean property, lovely room, great cafe located on the hotel property"
Canada
Emily
The price is AU$186
9 Sept - 10 Sept
Landmark Hotel

8. Hotel Iconik

Hotel Iconik
3.0 star property
Laureles - Estadio, 2 km from Santa Fe
9.2 out of 10, Wonderful, (11 reviews)
"Someone walk in my room when I was sleeping! I told them I was unsafe and uncomfortable and they did nothing to accommodate my stay!"
United States
Kailah
The price is AU$108
11 Aug - 12 Aug
Hotel Iconik

9. Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
Provenza, 2 km from Santa Fe
9.0 out of 10, Wonderful, (1,942 reviews)
"Great hotel, great location. Very quiet great pool good food good room, Affordable."
United States
thomas
The price is AU$148
6 Sept - 7 Sept
Dann Carlton Medellin Hotel

10. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego, 1.9 km from Santa Fe
8.8 out of 10, Excellent, (1,008 reviews)
"I like the hotel, staff was friendly, easy check in and check out, the breakfast was great and with a great variety of food."
United States
Gina
The price is AU$131
17 Aug - 18 Aug
La Quinta by Wyndham Medellin

11. HOTEL SELIS

HOTEL SELIS
3.5 star property
Zona Rosa, 2 km from Santa Fe
9.6 out of 10, Exceptional, (382 reviews)
"Great room and hotel!"
United States
Kevin
The price is AU$128
25 Aug - 26 Aug
HOTEL SELIS

12. Hotel San Fernando Plaza

Hotel San Fernando Plaza
4.0 star property
La Florida, 2.4 km from Santa Fe
9.2 out of 10, Wonderful, (1,019 reviews)
"Excellent property, friendly staff, great location"
United States
Karlene
The price is AU$151
23 Aug - 24 Aug
Hotel San Fernando Plaza

13. Wellcomm Spa & Hotel

Wellcomm Spa & Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.2 out of 10, Wonderful, (470 reviews)
"Excellent staff and value, safe location the spa is a must! "
United States
william
The price is AU$89
1 Sept - 2 Sept
Wellcomm Spa & Hotel

14. Manila Hotel Boutique

Manila Hotel Boutique
3.5 star property
Manila, 1.5 km from Santa Fe
9.2 out of 10, Wonderful, (318 reviews)
"We had a great stay overall. The breakfast was good, the room was clean, and the staff was friendly, kind, and always willing to help. The only downside was that the front rooms can be a bit noisy since you can hear traffic and other sounds from outside. Other than that, it’s a great place to stay for five days, and we would definitely recommend it."
United States
IRIS
The price is AU$86
10 Sept - 11 Sept
Manila Hotel Boutique

15. Lleras Green Hotel

Lleras Green Hotel
3.5 star property
Zona Rosa, 2.1 km from Santa Fe
8.2 out of 10, Very good, (1,007 reviews)
"Great place to stay.."
United States
Ronald
The price is AU$73
8 Sept - 9 Sept
Lleras Green Hotel

16. Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
Zona Rosa, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (2,168 reviews)
"It was close to stores, restaurants and the food was good."
United States
Juan
The price is AU$96
18 Aug - 19 Aug
Hashtag 98 Hotel By Jalo

17. Best Western Plus Hotel San Diego

Best Western Plus Hotel San Diego
3.5 star property
San Diego, 1.7 km from Santa Fe
8.8 out of 10, Excellent, (403 reviews)
"Clean room breakfast staff all good"
United States
Juan
The price is AU$134
16 Aug - 17 Aug
Best Western Plus Hotel San Diego

18. The Somos Central Hotel Poblado

The Somos Central Hotel Poblado
4.0 star property
Lalinde, 1.8 km from Santa Fe
9.0 out of 10, Wonderful, (375 reviews)
"Clean room, friendly staff; the food is very good and tasty"
United States
Catalina Carpio
The price is AU$98
31 Aug - 1 Sept
The Somos Central Hotel Poblado

19. 4 Sur Hotel

4 Sur Hotel
3.0 star property
Guayabal, 1.8 km from Santa Fe
9.4 out of 10, Exceptional, (238 reviews)
"The property was clean; rooms were on the small side but served its purpose. The staff was helpful as much as possible even though they spoke very little English…that’s when phone translator came in very handy. Overall, we enjoyed our stay. The only concern was the neighborhood. It wasn’t the best, however, we didn’t encounter any problems. Thanks you😊"
United States
Stanley McKee
The price is AU$87
14 Aug - 15 Aug
4 Sur Hotel

20. The Cut Hotel

The Cut Hotel
4.5 star property
Manila, 1.5 km from Santa Fe
9.4 out of 10, Exceptional, (42 reviews)
"The staff was soooo nice and helpful it made the stay even better. It was brand new so of course it was very clean."
United States
Colleen
The price is AU$116
8 Sept - 9 Sept
The Cut Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Fe

Find the best Santa Fe areas for the activities you enjoy most.

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza

If you're spending some time in Provenza, Galería Duque Arango and Lokkus Contemporary Art are top sights worth seeing.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top Santa Fe Hotel Reviews

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Frequently asked questions

What other neighbourhoods are similar to Santa Fe?
The best areas to stay that are similar to Santa Fe are Guatapé and Jardín.

Guatapé is a colourful town located about two hours east of Medellín, known for its unique 'zocalos' – brightly painted bas-reliefs adorning the lower parts of its buildings. The town sits beside the vast Peñol-Guatapé Reservoir, offering stunning lakeside views and opportunities for water activities. The most prominent landmark is El Peñol, a massive granite rock with 740 steps to the summit, providing panoramic views of the surrounding lakes and islands. It's a popular spot for travellers looking for scenic beauty and a taste of Colombian culture.

For couples, Guatapé offers a romantic escape with its picturesque streets and serene lake setting. You can take a boat trip on the reservoir, enjoy a meal at a waterside restaurant, or simply wander through the charming town centre, admiring the unique architecture. The climb up El Peñol can be a shared adventure, rewarded with breathtaking views.

Jardín is a more traditional and less touristy town, located in the coffee-growing region southwest of Medellín, about three hours away. It's characterised by its well-preserved historic architecture, with a large central plaza dominated by a neo-Gothic basilica. The town's slower pace of life and surrounding green hills dotted with coffee farms offer a tranquil experience. You'll find many locals gathered in the main square, enjoying coffee and conversation.

Solo travellers often appreciate Jardín for its authentic feel and opportunities to connect with local life. The town is small enough to explore on foot, and there are plenty of hiking trails in the nearby countryside, including paths to waterfalls and coffee plantations.
When is the best time to go to Santa Fe?
The best time to go to Santa Fe is during the dry season, which runs from December to March, and also in July and August.

During these months, you'll experience less rainfall and plenty of sunshine, making it ideal for exploring the town's historic architecture and enjoying outdoor activities. The weather is generally warm and pleasant, with average temperatures around 28°C (82°F) during the day. This period is superb for those who want to comfortably wander through the cobbled streets, visit the Puente de Occidente, or simply relax by a hotel pool.

The shoulder seasons, particularly April to June and September to November, can also be a good option if you prefer fewer crowds and potentially lower prices. While there might be more rain showers during these times, they often don't last all day, and you can still enjoy many attractions.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Santa Fe hotel for you.
How can I save on a hotel booking in Santa Fe with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Fe hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Fe?
Hotel prices in Santa Fe often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.

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