A cityscape with a prominent church featuring a red dome and white walls, surrounded by dense urban buildings and a busy street with yellow taxis.

Santa Fe Hotels, Medellín

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Our top choices for Santa Fe hotels

1. Hotel boutique Olaya 54

Hotel boutique Olaya 54
2.0 star property
Santa Fe
The price is AU$85
1 Oct - 2 Oct
Hotel boutique Olaya 54

2. Ayenda Casa San Pablo

Ayenda Casa San Pablo
2.5 star property
Santa Fe
8.0 out of 10, Very good, (7 reviews)
"Room was very small, the bathroom tiny and uncomfortable to navigate. Facilities were clean and the staff courteous."
United States
Jose
Ayenda Casa San Pablo

3. HOTEL CASA MEGUA3

HOTEL CASA MEGUA3
2.0 star property
Santa Fe
The price is AU$52
25 Oct - 26 Oct
HOTEL CASA MEGUA3

4. ibis Medellin

ibis Medellin
3.0 star property
0.8 km from Santa Fe
8.8 out of 10, Excellent, (1,001 reviews)
"Great location and staff were really friendly"
United States
Yuliana
The price is AU$84
24 Oct - 25 Oct
ibis Medellin

5. Heiss Hotel By Jalo

Heiss Hotel By Jalo
4.0 star property
El Poblado, 1.3 km from Santa Fe
9.2 out of 10, Wonderful, (1,903 reviews)
"Great stay"
United States
Marcus E
The price is AU$82
25 Oct - 26 Oct
Heiss Hotel By Jalo

6. La Quinta by Wyndham Medellin

La Quinta by Wyndham Medellin
3.5 star property
San Diego, 1.9 km from Santa Fe
9.0 out of 10, Wonderful, (1,001 reviews)
"The breakfast buffet was great!"
United States
Domingo
The price is AU$134
26 Sept - 27 Sept
La Quinta by Wyndham Medellin

7. V Grand Hotel, a member of Radisson Individuals

V Grand Hotel, a member of Radisson Individuals
3.5 star property
1.6 km from Santa Fe
9.2 out of 10, Wonderful, (1,376 reviews)
"Breakfast was outstanding"
Canada
Juan
The price is AU$143
17 Oct - 18 Oct
V Grand Hotel, a member of Radisson Individuals

8. Dann Carlton Medellin Hotel

Dann Carlton Medellin Hotel
4.5 star property
Provenza, 2 km from Santa Fe
9.0 out of 10, Wonderful, (2,020 reviews)
"Service, breakfast and location"
United States
Shawnis
The price is AU$150
27 Sept - 28 Sept
Dann Carlton Medellin Hotel

9. Golden Valley Hotel

Golden Valley Hotel
3.0 star property
Astorga, 1.6 km from Santa Fe
9.2 out of 10, Wonderful, (168 reviews)
"Great hotel in an excellent location."
United States
Nathaly
The price is AU$119
23 Oct - 24 Oct
Golden Valley Hotel

10. Manila Hotel Boutique

Manila Hotel Boutique
3.5 star property
Manila, 1.5 km from Santa Fe
9.2 out of 10, Wonderful, (337 reviews)
"Housekeeping really do there job and keep room very clean. The Person that make breakfast she is very attentive and go out of her way to make the best breakfast. The staff at the frontdesk is very helpfull try to help always and very kind always greetings if i pass 10 Times they will greet 10 times. I love the hotel and the hot tub :D"
United States
arnella
The price is AU$77
26 Sept - 27 Sept
Manila Hotel Boutique

11. Landmark Hotel

Landmark Hotel
4.0 star property
Manila, 1.4 km from Santa Fe
9.6 out of 10, Exceptional, (482 reviews)
"Great hotel"
United States
Adnan
The price is AU$161
30 Sept - 1 Oct
Landmark Hotel

12. Hotel Dix

Hotel Dix
3.0 star property
Zona Rosa, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (1,003 reviews)
"Good hotel"
United States
Sandra
The price is AU$120
25 Oct - 26 Oct
Hotel Dix

13. HOTEL SELIS

HOTEL SELIS
3.5 star property
Zona Rosa, 2 km from Santa Fe
9.6 out of 10, Exceptional, (396 reviews)
"Great room and hotel!"
United States
Kevin
The price is AU$109
29 Sept - 30 Sept
HOTEL SELIS

14. Hotel Park 10

Hotel Park 10
4.0 star property
Lalinde, 2.2 km from Santa Fe
9.4 out of 10, Exceptional, (1,528 reviews)
"Would stay here again.."
United States
Wilfred
The price is AU$162
25 Sept - 26 Sept
Hotel Park 10

15. Hashtag 98 Hotel By Jalo

Hashtag 98 Hotel By Jalo
4.0 star property
Zona Rosa, 1.9 km from Santa Fe
9.2 out of 10, Wonderful, (2,248 reviews)
"Amazing place to stay!!"
United States
Edel
The price is AU$97
28 Sept - 29 Sept
Hashtag 98 Hotel By Jalo

16. The Cut Hotel

The Cut Hotel
4.5 star property
Manila, 1.5 km from Santa Fe
9.2 out of 10, Wonderful, (86 reviews)
"Great hotel …..staff was amazing and food was amazing.Rooms were very well kept and beautiful. Would highly recommend this hotel to anyone."
United States
Arturo
The price is AU$99
1 Oct - 2 Oct
The Cut Hotel

17. Hotel Dann Carlton Belfort Medellin

Hotel Dann Carlton Belfort Medellin
4.0 star property
1.5 km from Santa Fe
8.8 out of 10, Excellent, (1,002 reviews)
"The food was great"
United States
Matthew
The price is AU$119
18 Oct - 19 Oct
Hotel Dann Carlton Belfort Medellin

18. ANTÍPODA HOTEL

ANTÍPODA HOTEL
3.0 star property
Patio Bonito, 1.7 km from Santa Fe
9.2 out of 10, Wonderful, (238 reviews)
"Quiet, nice, great staff! Felt safe the whole time I was there!"
United States
Arturo
The price is AU$111
25 Oct - 26 Oct
ANTÍPODA HOTEL

19. Moa Select

Moa Select
3.0 star property
Belen, 2.5 km from Santa Fe
9.4 out of 10, Exceptional, (397 reviews)
"Best place to stay in Belen"
United States
Dargel
The price is AU$77
25 Sept - 26 Sept
Moa Select

20. 4 Sur Hotel

4 Sur Hotel
3.0 star property
Guayabal, 1.8 km from Santa Fe
9.4 out of 10, Exceptional, (245 reviews)
"Staff excellent and de breakfast"
United States
Jean
The price is AU$73
25 Oct - 26 Oct
4 Sur Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Santa Fe

Find the best Santa Fe areas for the activities you enjoy most.

El Poblado

El Poblado is highly notable for its popular shops, and you might want to visit top sights like Golden Mile and Oviedo Shopping Center. See more of Medellín by jumping on the metro at Poblado Station or Aguacatala Station.

Laureles

Laureles is known for its ample dining options, and you can make a stop by Unicentro Shopping Center and Belén Andrés Escobar Sports Complex while in the area.

Provenza

If you're spending some time in Provenza, Galería Duque Arango and Lokkus Contemporary Art are top sights worth seeing.

Laureles - Estadio

While you're in Laureles - Estadio, take in top sights like Atanasio Giradot Stadium or Unicentro Shopping Center, and hop on the metro to see more of the city at Estadio Station or Suramericana Station.

Zona Rosa

When in Zona Rosa, you can plan a visit to Golden Mile and Oviedo Shopping Center, some noteworthy sights in the nearby area.

Top Santa Fe Hotel Reviews

Recent Reviews in Santa Fe

Frequently asked questions

What other neighbourhoods are similar to Santa Fe?
The best areas to stay that are similar to Santa Fe are Guatapé and Jardín.

Guatapé is a colourful town located about two hours east of Medellín, known for its unique 'zocalos' – brightly painted bas-reliefs adorning the lower parts of its buildings. The town sits beside the vast Peñol-Guatapé Reservoir, offering stunning lakeside views and opportunities for water activities. The most prominent landmark is El Peñol, a massive granite rock with 740 steps to the summit, providing panoramic views of the surrounding lakes and islands. It's a popular spot for travellers looking for scenic beauty and a taste of Colombian culture.

For couples, Guatapé offers a romantic escape with its picturesque streets and serene lake setting. You can take a boat trip on the reservoir, enjoy a meal at a waterside restaurant, or simply wander through the charming town centre, admiring the unique architecture. The climb up El Peñol can be a shared adventure, rewarded with breathtaking views.

Jardín is a more traditional and less touristy town, located in the coffee-growing region southwest of Medellín, about three hours away. It's characterised by its well-preserved historic architecture, with a large central plaza dominated by a neo-Gothic basilica. The town's slower pace of life and surrounding green hills dotted with coffee farms offer a tranquil experience. You'll find many locals gathered in the main square, enjoying coffee and conversation.

Solo travellers often appreciate Jardín for its authentic feel and opportunities to connect with local life. The town is small enough to explore on foot, and there are plenty of hiking trails in the nearby countryside, including paths to waterfalls and coffee plantations.
When is the best time to go to Santa Fe?
The best time to go to Santa Fe is during the dry season, which runs from December to March, and also in July and August.

During these months, you'll experience less rainfall and plenty of sunshine, making it ideal for exploring the town's historic architecture and enjoying outdoor activities. The weather is generally warm and pleasant, with average temperatures around 28°C (82°F) during the day. This period is superb for those who want to comfortably wander through the cobbled streets, visit the Puente de Occidente, or simply relax by a hotel pool.

The shoulder seasons, particularly April to June and September to November, can also be a good option if you prefer fewer crowds and potentially lower prices. While there might be more rain showers during these times, they often don't last all day, and you can still enjoy many attractions.
Can I cancel my hotel reservation on Expedia?
Many Expedia hotel reservations are refundable, provided that you cancel before the hotel's cancellation deadline − this is often within 24 to 48 hours of your scheduled arrival. If you have a non-refundable booking, it might still be possible to receive a refund if you cancel it within 24 hours of booking. Be sure to check your booking confirmation for the exact cancellation policy. For maximum flexibility, use our 'Fully refundable property' filter during your search to find the right Santa Fe hotel for you.
How can I save on a hotel booking in Santa Fe with Expedia?
One Key™—Expedia's free travel rewards program—gives you instant access to discounts with Member Prices on Santa Fe hotels. Plus, you'll earn OneKeyCash™* on eligible bookings to use on future trips. Booking an Expedia hotel and flight package is another great way to save, where bundling can result in significant savings. *Excludes taxes and fees. OneKeyCash is not redeemable for cash and can only be used on Expedia and other participating brands.
How much is the nightly rate for a hotel in Santa Fe?
Hotel prices in Santa Fe often vary, but you can find a great deal on Expedia. Different factors affect nightly hotel rates, such as the time of year or the days of the week you want to book. To find the best deals for your stay, be flexible with your dates and sort search results by 'Price: low to high' for our cheapest rates.

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