Photo by Panama Roadrunner

San Francisco Hotels, Panama City

Start date: Check-in selected.
To Date
End date: Check-out

    Change your mind

    Book hotels with free cancellation

    Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

    Be picky

    Search almost a million properties worldwide

Check prices for these dates

Tonight
24 Oct - 25 Oct
Tomorrow
25 Oct - 26 Oct
This weekend
24 Oct - 26 Oct
Next weekend
31 Oct - 2 Nov

Filter by

Guest rating
Guest rating
Star rating

1547 Cheap Hotels in San Francisco - Specials, Reviews, & Last Minute Deals

Daily cooked-to-order breakfast (USD 15.00 per person)
Courtyard by Marriott Panama Multiplaza Mall
Courtyard by Marriott Panama Multiplaza Mall
4.0 star property
8.8 out of 10, Excellent, (1004)
"Perfect stay "
United States
pedro
The price is AU$195
includes taxes & fees
1 Nov - 2 Nov
Courtyard by Marriott Panama Multiplaza Mall
Exterior
Aloft Panama
Aloft Panama
3.5 star property
8.6 out of 10, Excellent, (869)
"Was please with the hospitality and the front desk staff Aaron was very professional and informative "
United States
Latoya
The price is AU$198
includes taxes & fees
1 Nov - 2 Nov
Aloft Panama
Outdoor pool, pool umbrellas, pool loungers
Ramada Plaza by Wyndham Panama Punta Pacifica
Ramada Plaza by Wyndham Panama Punta Pacifica
4.0 star property
9.6 out of 10, Exceptional, (1078)
"Good place to stay, convenient and the service was very good "
United States
Jannette
The price is AU$184
includes taxes & fees
22 Nov - 23 Nov
Ramada Plaza by Wyndham Panama Punta Pacifica
Terrace/patio
Sheraton Grand Panama
Sheraton Grand Panama
4.0 star property
8.6 out of 10, Excellent, (968)
"Centrally located and friendly staff "
United States
Julio
The price is AU$226
includes taxes & fees
1 Nov - 2 Nov
Sheraton Grand Panama
Front of property
Megapolis Hotel Panamá
Megapolis Hotel Panamá
4.5 star property
8.4 out of 10, Very good, (1146)
"Great stay "
United States
Mark
The price is AU$211
includes taxes & fees
23 Nov - 24 Nov
Megapolis Hotel Panamá
View from property
Plaza Paitilla Inn Hotel
Plaza Paitilla Inn Hotel
3.5 star property
9.4 out of 10, Exceptional, (2114)
"Breakfast was great, friendly staff and walking distance to a small mall"
United States
Troy
The price is AU$267
includes taxes & fees
26 Oct - 27 Oct
Plaza Paitilla Inn Hotel
Outdoor pool
Boutique Apartments Panamá Coco del Mar
Boutique Apartments Panamá Coco del Mar
3.5 star property
7.4 out of 10, Good, (145)
"Beautiful view! "
United States
Kenisha
The price is AU$272
includes taxes & fees
29 Oct - 30 Oct
Boutique Apartments Panamá Coco del Mar
4 outdoor pools, free pool cabanas, pool umbrellas
JW Marriott Panama
JW Marriott Panama
5.0 star property
9.0 out of 10, Wonderful, (1002)
"Room service, clean room, excellent food"
United States
Donald
The price is AU$372
includes taxes & fees
7 Nov - 8 Nov
JW Marriott Panama
Outdoor pool
Boutique Apartments Atlapa
Boutique Apartments Atlapa
3.0 star property
7.6 out of 10, Good, (23)
"I had an excellent stay here ! It was a very amazing the host is an amazing person thank you for making My stay great❤️"
United States
Shamia
Boutique Apartments Atlapa
Exterior
Decapolis Hotel Panama City
Decapolis Hotel Panama City
4.0 star property
8.6 out of 10, Excellent, (1374)
"Very nice Hotel "
United States
Marcos
The price is AU$142
includes taxes & fees
26 Oct - 27 Oct
Decapolis Hotel Panama City
View from property
Las Americas Golden Tower Panama
Las Americas Golden Tower Panama
4.0 star property
9.0 out of 10, Wonderful, (1020)
"We ejoyed our stay here, very nice pool and gym area."
United States
Prentice
The price is AU$219
includes taxes & fees
27 Oct - 28 Oct
Las Americas Golden Tower Panama
Lobby sitting area
San Francisco by Wynwood House
San Francisco by Wynwood House
3.0 star property
9.2 out of 10, Wonderful, (51)
"This area was perfect for us to walk and check out the local restaurants and coffee shops was really an amazing time! Very close to other major areas so driving and getting around was very convenient:))) all around great stay! "
United States
mario
The price is AU$183
includes taxes & fees
26 Oct - 27 Oct
San Francisco by Wynwood House
Outdoor pool, open 6:00 AM to 11:00 PM, pool umbrellas, pool loungers
Residence Inn by Marriott Panama City
Residence Inn by Marriott Panama City
4.0 star property
9.0 out of 10, Wonderful, (521)
"Stayed here while a relative was hospitalized, easy access to the hospital and shopping center with lots of food options. If visiting Panama city it is very conveniently located."
United States
Luis
The price is AU$243
includes taxes & fees
9 Nov - 10 Nov
Residence Inn by Marriott Panama City
Terrace/patio
Casa Orquídea
Casa Orquídea
2.0 star property
9.0 out of 10, Wonderful, (2)
"For me was very convenient "
United States
Natalia
The price is AU$128
includes taxes & fees
1 Nov - 2 Nov
Casa Orquídea
Outdoor pool
Wanders Panama by Boutique Apartments
Wanders Panama by Boutique Apartments
4.0 star property
10.0 out of 10, Exceptional, (1)
"I will go again thank you so much"
United States
GISY ITZEL
The price is AU$372
includes taxes & fees
29 Oct - 30 Oct
Wanders Panama by Boutique Apartments
Apartment
w Bright 1BR w Private Balcony in San Francisco
w Bright 1BR w Private Balcony in San Francisco
2.0 star property
The price is AU$198
includes taxes & fees
26 Oct - 27 Oct
w Bright 1BR w Private Balcony in San Francisco
Apartment
w Premium 1BR w Balcony in San Francisco
w Premium 1BR w Balcony in San Francisco
2.0 star property
The price is AU$209
includes taxes & fees
6 Nov - 7 Nov
w Premium 1BR w Balcony in San Francisco
47-inch flat-screen TV with cable channels, TV
Central Hotel Panama Casco Viejo
Central Hotel Panama Casco Viejo
4.0 star property
9.2 out of 10, Wonderful, (1002)
"Very beautiful hotel with helpful staff. Very good dining options. "
United States
Joseph
The price is AU$333
includes taxes & fees
26 Oct - 27 Oct
Central Hotel Panama Casco Viejo
Outdoor pool, pool umbrellas, pool loungers
Crowne Plaza Panama Airport by IHG
Crowne Plaza Panama Airport by IHG
4.0 star property
8.4 out of 10, Very good, (2264)
"Great location "
United States
Juan
The price is AU$204
includes taxes & fees
1 Nov - 2 Nov
Crowne Plaza Panama Airport by IHG
Outdoor pool, pool loungers
Hotel Riu Plaza Panama
Hotel Riu Plaza Panama
5.0 star property
9.0 out of 10, Wonderful, (4415)
"Great stay, clean, great restaurants, nearby for business travels"
United States
Christian
The price is AU$193
includes taxes & fees
9 Nov - 10 Nov
Hotel Riu Plaza Panama
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Our guide on where to stay in San Francisco

Find the best San Francisco areas for the activities you enjoy most.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Interoceanic Canal Museum or National Theater while you're exploring the area.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Crown Casino or Luxor Towers might round out your trip.

San Felipe

While visiting San Felipe, you might make a stop by sights like Interoceanic Canal Museum and National Theater.

Punta Paitilla

Punta Paitilla is known for its abundant dining options, and you can plan a trip to Avenida Balboa and Multicentro Panama while you're in town.

Top San Francisco Hotel Reviews

Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo

10/10 Excellent
"Great hotel, clean, pretty , located right in the middle of Old Panama. Great experience. Staff more than friendly"
Francisco Manuel 4-night trip
Posted 4 days ago
Central Hotel Panama Casco Viejo

Frequently asked questions

What is San Francisco like?
San Francisco is a welcoming neighbourhood that travellers like for its restaurants. Make sure that you visit Multiplaza Pacific Mall and Calle 50 as part of your San Francisco travel plans.
Where is the best hotel for a stay in San Francisco?
Based on Expedia customer reviews, Ramada Plaza by Wyndham Panama Punta Pacifica is the highest ranked property in San Francisco. This hotel is a short 4-minute walk from Multiplaza Pacific Mall, and it offers free breakfast and a restaurant. Other top choices in the neighbourhood include Plaza Paitilla Inn Hotel and Residence Inn by Marriott Panama City.
How many hotels can I expect to find in San Francisco?
If you're searching for places to stay in Panama City, Expedia has something to meet your needs with 212 San Francisco hotels and other accommodation options to choose from.
If I need to cancel my hotel reservation in San Francisco, will I receive a refund?
Yes! Most hotel reservations are fully refundable provided that you cancel before the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, you may still be able to cancel and be given a refund within 24 hours of booking. Add dates, click "Search", then use the filter option "fully refundable" to view the best deals in San Francisco.
What is there to do in this Panama City neighbourhood?
While you're in San Francisco, a shopping trip to Multiplaza Pacific Mall, Avenida Balboa or Pacific Center might be the perfect way to find that souvenir you've been looking for. Calle 50 and Panama Canal Murals are some other stops worth a visit in the neighbourhood. A few places to visit in the area around San Francisco include Colonial Religious Art Museum, Bingo 90 and Soho City Center. When you're sightseeing in Panama City, National Shrine of the Heart of Mary and Panama Viejo Museum are also worth a stop.

Explore a world of travel with Expedia