
San Francisco Holidays from AU$1,307
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Your San Francisco Holiday
From its highlights to its hidden treasures, this city is best experienced with a San Francisco holiday package. Find a place to stay in El Cangrejo, which is good for distilleries and craft breweries, bars and pubs and cafes. Every trip to San Francisco needs a well-designed itinerary. Fill yours with famous sights like Miraflores Locks, Bridge of the Americas and Metropolitan Cathedral of Panama. Your ideal San Francisco holiday is only clicks away. Browse airfares, hotels and more on Expedia for a getaway that's tailored just for you.
Top Holiday Package Deals in San Francisco

Megapolis Hotel Panamá
Reviewed on 26 Nov 2025

Central Hotel Panama Casco Viejo
Reviewed on 23 Nov 2025

Amarla Boutique Hotel Casco Viejo
Reviewed on 18 Nov 2025

Casa Lefevre By Wynwood House
Reviewed on 8 Sept 2025

Yoo by Wynwood House
Reviewed on 26 July 2025
Our guide on where to stay in San Francisco

Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Our pick of the best San Francisco Hotel Deals

Las Americas Golden Tower Panama
Clean room
Reviewed on 24 Nov 2025

Sheraton Grand Panama
Excelente atención y servicio La cuna de bebé era de material como fierro, insegura para bebés que ya se paran un poco El área de juegos de niños siempre mojada y no tenía protección solar podría adecuarse mejor
Reviewed on 1 Nov 2025

Megapolis Hotel Panamá
Muy buenos cuartos y servicios El spa y el desayuno son en 100 Siempre que venimos a la Coudad es nuestro hospedaje de selección
Reviewed on 26 Nov 2025
Frequently asked questions
Discover the most popular places to visit in San Francisco

Multiplaza Pacific Mall
During your trip to Panama City, you can search for that perfect souvenir at Multiplaza Pacific Mall. You can enjoy the restaurants while in the area.
Activities

Panama City: Poin Glass Observation Deck Ticket with VR Tour

Panama City: Poin Full Package Experience













