Serra Mesa Hotels, San Diego
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Our top choices for Serra Mesa hotels
Best Western Americana Inn
Best Western Americana Inn28.1 km from Serra Mesa
8.8 out of 10, Excellent, (1,298 reviews)
"Room is nice, clean, & breakfast is good. We always stay here when in the area."
Travis
The price is AU$197
includes taxes & fees
14 June - 15 June
Best Western Plus Marina Gateway Hotel
Best Western Plus Marina Gateway Hotel16.1 km from Serra Mesa
9.2 out of 10, Wonderful, (3,876 reviews)
"Great stay"
Cameron
The price is AU$280
includes taxes & fees
28 June - 29 June
Ayres Hotel San Diego South - Chula Vista
Ayres Hotel San Diego South - Chula Vista26 km from Serra Mesa
9.8 out of 10, Exceptional, (1,103 reviews)
"Nice place good food for breakfast 👍"
Paul
The price is AU$334
includes taxes & fees
6 July - 7 July
Hampton Inn & Suites San Diego Airport Liberty Station
Hampton Inn & Suites San Diego Airport Liberty Station10.6 km from Serra Mesa
9.2 out of 10, Wonderful, (1,727 reviews)
"Good location, clean room and nice staff. A great place to stay."
Patricia
The price is AU$280
includes taxes & fees
28 June - 29 June
Holiday Inn Express San Diego South - Chula Vista by IHG
Holiday Inn Express San Diego South - Chula Vista by IHG18.5 km from Serra Mesa
9.4 out of 10, Exceptional, (1,225 reviews)
"Room fit our family of 6 and the breakfast was good."
Jamie
The price is AU$237
includes taxes & fees
6 July - 7 July
Comfort Inn Chula Vista San Diego South
Comfort Inn Chula Vista San Diego South18.6 km from Serra Mesa
8.2 out of 10, Very good, (1,541 reviews)
"Everything was excellent. Room, breakfast location and staff. This was our second time staying here and we'll be back."
Chris
The price is AU$198
includes taxes & fees
28 June - 29 June
Embassy Suites by Hilton San Diego La Jolla
Embassy Suites by Hilton San Diego La JollaUniversity City, 10.3 km from Serra Mesa
8.8 out of 10, Excellent, (1,925 reviews)
"Great location and very comfortable and spacious hotel room"
Carmen
The price is AU$374
includes taxes & fees
21 June - 22 June
Sheraton San Diego Resort
Sheraton San Diego Resort10.1 km from Serra Mesa
8.4 out of 10, Very good, (3,557 reviews)
"My family and I truly enjoyed our stay."
Beverly A
The price is AU$331
includes taxes & fees
5 July - 6 July
Sycuan Casino Resort
Sycuan Casino Resort28.8 km from Serra Mesa
9.4 out of 10, Exceptional, (1,969 reviews)
"Always a great stay"
Jeanette
The price is AU$224
includes taxes & fees
9 June - 10 June
Courtyard by Marriott San Diego Central
Courtyard by Marriott San Diego Central2.6 km from Serra Mesa
8.8 out of 10, Excellent, (1,018 reviews)
"Great hotel and I will stay there again. Good breakfast and very clean and safe."
Natalie
The price is AU$272
includes taxes & fees
5 July - 6 July
Best Western San Diego/Miramar Hotel
Best Western San Diego/Miramar Hotel10.1 km from Serra Mesa
8.0 out of 10, Very good, (1,377 reviews)
"Great stay
Really close to the cut water brewery!"
Jessica
The price is AU$207
includes taxes & fees
14 June - 15 June
La Quinta Inn by Wyndham San Diego Chula Vista
La Quinta Inn by Wyndham San Diego Chula Vista18.7 km from Serra Mesa
8.6 out of 10, Excellent, (1,636 reviews)
"Great place to stay at, would definitely stay there again."
Jose
The price is AU$167
includes taxes & fees
14 June - 15 June
Country Inn & Suites by Radisson, San Diego North, CA
Country Inn & Suites by Radisson, San Diego North, CA11.7 km from Serra Mesa
9.0 out of 10, Wonderful, (1,509 reviews)
"Very great stay"
Phillip
The price is AU$298
includes taxes & fees
21 June - 22 June
HYATT house San Diego/Sorrento Mesa
HYATT house San Diego/Sorrento Mesa11.8 km from Serra Mesa
9.2 out of 10, Wonderful, (1,018 reviews)
"Amazing stay"
Kevin
The price is AU$297
includes taxes & fees
21 June - 22 June
Holiday Inn Express San Diego Airport - Old Town by IHG
Holiday Inn Express San Diego Airport - Old Town by IHG7.9 km from Serra Mesa
9.2 out of 10, Wonderful, (1,075 reviews)
"Staff was so great nice rooms really great stay"
Amelia
The price is AU$264
includes taxes & fees
1 July - 2 July
Ramada by Wyndham San Diego Poway Miramar
Ramada by Wyndham San Diego Poway Miramar18.2 km from Serra Mesa
7.2 out of 10, Good, (1,021 reviews)
"Nice place to stay."
Jacquie
The price is AU$193
includes taxes & fees
14 June - 15 June
Hampton Inn Cardiff Beach Encinitas, CA Near Del Mar
Hampton Inn Cardiff Beach Encinitas, CA Near Del Mar28 km from Serra Mesa
9.2 out of 10, Wonderful, (1,040 reviews)
"Great location and comfortable beds!"
Michael
The price is AU$286
includes taxes & fees
14 June - 15 June
Hilton Garden Inn San Diego Old Town/SeaWorld Area
Hilton Garden Inn San Diego Old Town/SeaWorld AreaOld Town San Diego, 7.4 km from Serra Mesa
8.8 out of 10, Excellent, (1,468 reviews)
"Hotel is lovely mission style in keeping with the area. The location is very convenient to local attractions."
Toni
The price is AU$260
includes taxes & fees
28 June - 29 June
San Diego Mission Bay Resort
San Diego Mission Bay ResortMission Bay, 7.2 km from Serra Mesa
8.6 out of 10, Excellent, (1,468 reviews)
"Great resort!"
Jean-Michelle
The price is AU$546
includes taxes & fees
14 June - 15 June
Courtyard by Marriott San Diego Airport/Liberty Station
Courtyard by Marriott San Diego Airport/Liberty Station10.7 km from Serra Mesa
9.2 out of 10, Wonderful, (1,300 reviews)
"Great location, good parking, great staff."
Rosemary
The price is AU$290
includes taxes & fees
14 June - 15 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Serra Mesa
Find the best Serra Mesa areas for the activities you enjoy most.
Downtown San Diego
Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and USS Midway Museum are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.
Pacific Beach
Get to Pacific Beach after the sun goes down because this is the place to be in San Diego for partying.
Mission Beach
If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.
Gaslamp Quarter
The historic heart of San Diego has a fascinating history, and today is a thriving hub for food, retail and entertainment.
Mission Bay
If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.
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