Top Hotels Near Mayo Clinic Scottsdale in Phoenix from AU$130

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Our top choices for Mayo Clinic Scottsdale hotels

Lobby lounge
Sonesta Select Scottsdale at Mayo Clinic Campus

Sonesta Select Scottsdale at Mayo Clinic Campus

3.0 star property
0.3 km from Mayo Clinic Scottsdale
8.2 out of 10, Very good, (1050)
"Very clean and very friendly staff "
United States
Michelle
The price is AU$170
includes taxes & fees
28 Dec - 29 Dec
Sonesta Select Scottsdale at Mayo Clinic Campus
Mountain view
Inn at Eagle Mountain

Inn at Eagle Mountain

3.5 star property
3.1 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1000)
"Beautiful rooms, great views and a very peaceful stay"
United States
Roberta
Inn at Eagle Mountain
View from property
ADERO Scottsdale Resort, Autograph Collection

ADERO Scottsdale Resort, Autograph Collection

4.5 star property
3.6 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (903)
"Very clean with beautiful rooms and scenery. "
United States
LaKeisha
The price is AU$358
includes taxes & fees
28 Dec - 29 Dec
ADERO Scottsdale Resort, Autograph Collection
Lobby
Comfort Suites Scottsdale Talking Stick Entertainment District

Comfort Suites Scottsdale Talking Stick Entertainment District

2.5 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1752)
"The property was easy to find, clean, the beds were comfortable and the free breakfast was good."
United States
Jackie
The price is AU$153
includes taxes & fees
28 Dec - 29 Dec
Comfort Suites Scottsdale Talking Stick Entertainment District
Exterior
Talking Stick Resort

Talking Stick Resort

4.0 star property
8.8 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (4174)
"Very clean; friendly staff - truly great place to stay. "
United States
Brandon
The price is AU$289
includes taxes & fees
14 Dec - 15 Dec
Talking Stick Resort
Reception
Fountain Park Hotel, BW Signature Collection

Fountain Park Hotel, BW Signature Collection

3.0 star property
7.3 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1001)
"Courteous staff, quick check in/out, clean room."
United States
Johnny
The price is AU$171
includes taxes & fees
15 Dec - 16 Dec
Fountain Park Hotel, BW Signature Collection
View from room
Spark by Hilton Fountain Hills Scottsdale

Spark by Hilton Fountain Hills Scottsdale

2.5 star property
7.6 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (164)
"Clean room, nice staff!"
United States
Alex Morrow
The price is AU$130
includes taxes & fees
21 Dec - 22 Dec
Spark by Hilton Fountain Hills Scottsdale
Gazebo
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

La Quinta Inn & Suites by Wyndham Phoenix Scottsdale

3.0 star property
Central Scottsdale, 8.9 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1768)
" Great stay."
United States
Mark
The price is AU$149
includes taxes & fees
22 Dec - 23 Dec
La Quinta Inn & Suites by Wyndham Phoenix Scottsdale
Outdoor pool
Aiden by Best Western Scottsdale North

Aiden by Best Western Scottsdale North

3.0 star property
8.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1007)
"Great stay! "
United States
Nichelle
The price is AU$159
includes taxes & fees
15 Dec - 16 Dec
Aiden by Best Western Scottsdale North
Outdoor pool, pool umbrellas, pool loungers
Tru By Hilton Scottsdale Salt River

Tru By Hilton Scottsdale Salt River

2.5 star property
8.9 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (901)
"It was a pleasure to stay there "
United States
Anthony
The price is AU$150
includes taxes & fees
21 Dec - 22 Dec
Tru By Hilton Scottsdale Salt River
Outdoor pool, pool loungers
Holiday Inn Hotel & Suites Scottsdale North - Airpark by IHG

Holiday Inn Hotel & Suites Scottsdale North - Airpark by IHG

3.5 star property
9.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (834)
"Great front desk staff. "
Canada
Mark
The price is AU$141
includes taxes & fees
23 Dec - 24 Dec
Holiday Inn Hotel & Suites Scottsdale North - Airpark by IHG
Suite, 2 Bedrooms, Kitchen
Staybridge Suites Scottsdale - Talking Stick by IHG

Staybridge Suites Scottsdale - Talking Stick by IHG

3.0 star property
9.7 km from Mayo Clinic Scottsdale
9.4 out of 10, Exceptional, (959)
"Great breakfast "
United States
Jenny
The price is AU$203
includes taxes & fees
4 Jan - 5 Jan 2026
Staybridge Suites Scottsdale - Talking Stick by IHG
Restaurant
Hampton Inn & Suites Scottsdale at Talking Stick

Hampton Inn & Suites Scottsdale at Talking Stick

3.0 star property
9.1 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1003)
"Nice place Friendly staff "
United States
Robert
The price is AU$178
includes taxes & fees
21 Dec - 22 Dec
Hampton Inn & Suites Scottsdale at Talking Stick
Exterior
Home2 Suites by Hilton Scottsdale Salt River

Home2 Suites by Hilton Scottsdale Salt River

3.0 star property
9.6 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (576)
"Great stay!"
United States
Chris
The price is AU$143
includes taxes & fees
21 Dec - 22 Dec
Home2 Suites by Hilton Scottsdale Salt River
Terrace/patio
Wekopa Casino Resort

Wekopa Casino Resort

4.0 star property
10.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1000)
"Great place "
United States
Eric
Wekopa Casino Resort
Outdoor pool, open 6:00 AM to midnight, pool umbrellas, pool loungers
Hilton Garden Inn Scottsdale North/Perimeter Center

Hilton Garden Inn Scottsdale North/Perimeter Center

3.0 star property
11.7 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (1000)
"Super clean, friendly staff, happy to be pet friendly"
United States
Diana
The price is AU$164
includes taxes & fees
24 Dec - 25 Dec
Hilton Garden Inn Scottsdale North/Perimeter Center
Outdoor pool
Sonesta Simply Suites Phoenix Scottsdale

Sonesta Simply Suites Phoenix Scottsdale

2.5 star property
8.6 km from Mayo Clinic Scottsdale
8.0 out of 10, Very good, (1005)
"Everything was great clean and the staff was friendly "
United States
Steven
The price is AU$149
includes taxes & fees
28 Dec - 29 Dec
Sonesta Simply Suites Phoenix Scottsdale
Exterior
Holiday Inn Express Scottsdale North by IHG

Holiday Inn Express Scottsdale North by IHG

2.5 star property
Central Scottsdale, 12 km from Mayo Clinic Scottsdale
8.8 out of 10, Excellent, (1007)
"Exceeded our expectations!"
United States
Robert
The price is AU$131
includes taxes & fees
28 Dec - 29 Dec
Holiday Inn Express Scottsdale North by IHG
Mini-golf
Great Wolf Lodge Arizona

Great Wolf Lodge Arizona

4.0 star property
10.2 km from Mayo Clinic Scottsdale
9.0 out of 10, Wonderful, (900)
"Love the scavenger hunt and water playground "
United States
Shantel
The price is AU$285
includes taxes & fees
7 Jan - 8 Jan 2026
Great Wolf Lodge Arizona
Exterior
Hilton Vacation Club Scottsdale Links Resort

Hilton Vacation Club Scottsdale Links Resort

3.5 star property
11.3 km from Mayo Clinic Scottsdale
9.2 out of 10, Wonderful, (1007)
"Great place for families"
Canada
Raluca
The price is AU$268
includes taxes & fees
4 Jan - 5 Jan 2026
Hilton Vacation Club Scottsdale Links Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Mayo Clinic Scottsdale Hotel Reviews

Talking Stick Resort

Talking Stick Resort

10/10 Excellent
"Outstanding property!!! Rooms were awesome service and food top notch. "
Lee 1-night trip
Posted 8 hours ago
Talking Stick Resort

Hotels near other Mayo Clinic Scottsdale attractions

Eagle Mountain Golf Course

4.4/5 (64 reviews)
Play a round of golf at Eagle Mountain Golf Course and enjoy other activities in Fountain Hills such as running. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
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Golf Club at Eagle Mountain

4.3/5 (44 reviews)
Play a round of golf at Golf Club at Eagle Mountain and enjoy other activities in Fountain Hills such as running. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
See properties

Frequently asked questions

What's the area like around Mayo Clinic Scottsdale?
Mayo Clinic Scottsdale is located in a welcoming area of Scottsdale known for its array of dining options and sporting events. If you're looking for a convenient place to stay, take a look at the 41 hotels and other accommodation options you'll find within a mile.
What's the best hotel to stay near Mayo Clinic Scottsdale?
Adjacent to Mayo Clinic Scottsdale, Sonesta Select Scottsdale at Mayo Clinic Campus is one of the top choices for your stay based on our traveller data, and this hotel offers a restaurant and an outdoor pool. Other good choices within 5 miles include ADERO Scottsdale Resort, Autograph Collection and Inn at Eagle Mountain.
How many hotels will I find close to Mayo Clinic Scottsdale?
Expedia has 41 hotels and other accommodation options within a mile from Mayo Clinic Scottsdale.
If I need to cancel the hotel reservation for my stay near Mayo Clinic Scottsdale, will I receive a refund?
Yes, most hotel room reservations are refundable if you cancel prior to the hotel's cancellation deadline, which often is within 24-48 hours of check in. If you booked a non-refundable reservation, it might still be possible to cancel it and receive a refund within 24 hours of booking. Plug in your dates, click on "Search", then you can use the "fully refundable" filter to get the best deals available near Mayo Clinic Scottsdale.
What can I see and do near Mayo Clinic Scottsdale?
You might spend a leisurely day outdoors at Scottsdale Ranch Park and Fountain Hills Botanical Garden. Explore nature at Desert Sonoran Botanical Garden Trailhead and Golden Eagle Trailhead. Eagle Mountain Golf Course, SunRidge Canyon Golf Club or Golf Club at Eagle Mountain are some local sights worth checking out.

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