Top Hotels Near Louisville Science Center in Louisville

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Accommodation near Louisville Science Center

Free daily full breakfast
Market Street Inn

Market Street Inn

3.5 star property
2.1 km from Louisville Science Center
9.8 out of 10, Exceptional, (120)
"I enjoyed my stay, however the breakfast portion was very small even for a petite person like myself, I was still very hungry after breakfast. There was a cleaning issue with the bathroom that was overlooked by the cleaning staff that I alerted the owners to that will hopefully be fixed for future visitors. The house is great and very clean overall. The owners are very nice."
United States
Megan
The price is AU$320
includes taxes & fees
2 Dec - 3 Dec
Market Street Inn
Front of property
DuPont Mansion Bed & Breakfast

DuPont Mansion Bed & Breakfast

3.0 star property
Old Louisville, 2.8 km from Louisville Science Center
9.8 out of 10, Exceptional, (95)
"Breakfast was wonderful, great place to stay!"
United States
Janie
The price is AU$225
includes taxes & fees
8 Dec - 9 Dec
DuPont Mansion Bed & Breakfast
Exterior
Hotel Distil, Autograph Collection

Hotel Distil, Autograph Collection

4.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.6 out of 10, Exceptional, (427)
"Really a nice place to stay "
United States
Jeanie
The price is AU$304
includes taxes & fees
14 Dec - 15 Dec
Hotel Distil, Autograph Collection
Signature Suite, 1 Queen Bed, Non Smoking
Stellar Suites

Stellar Suites

4.5 star property
East Market District, 2.2 km from Louisville Science Center
9.6 out of 10, Exceptional, (116)
"Clean and great location "
United States
Greg
The price is AU$274
includes taxes & fees
1 Jan - 2 Jan 2026
Stellar Suites
Deluxe Single Room, 1 King Bed, River View | View from room
The Grady

The Grady

4.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1015)
"The location was outstanding and atmosphere was very nice."
United States
Malcolm
The price is AU$263
includes taxes & fees
21 Dec - 22 Dec
The Grady
Lobby
The Brown Hotel

The Brown Hotel

4.5 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1144)
"Wonderful hotel with lots of history; clean rooms; Nice lounge and restaurants."
United States
Kim
The price is AU$212
includes taxes & fees
2 Dec - 3 Dec
The Brown Hotel
Dining
Cambria Hotel Louisville Downtown-Whiskey Row

Cambria Hotel Louisville Downtown-Whiskey Row

3.0 star property
Downtown Louisville, 1.2 km from Louisville Science Center
9.4 out of 10, Exceptional, (1020)
"Lovely hotel."
United States
Nancy
The price is AU$142
includes taxes & fees
24 Dec - 25 Dec
Cambria Hotel Louisville Downtown-Whiskey Row
2 restaurants, breakfast served
Tempo By Hilton Louisville Downtown Nulu

Tempo By Hilton Louisville Downtown Nulu

3.5 star property
Phoenix Hill, 2.1 km from Louisville Science Center
9.4 out of 10, Exceptional, (805)
"Love the hotel and will always stay there when visiting "
United States
Jeremy
The price is AU$171
includes taxes & fees
19 Dec - 20 Dec
Tempo By Hilton Louisville Downtown Nulu
Exterior detail
Central Park Bed & Breakfast

Central Park Bed & Breakfast

4.0 star property
Old Louisville, 3 km from Louisville Science Center
9.4 out of 10, Exceptional, (56)
"The room was beautiful, breakfast was delicious and the park across the street was lovely. I especially enjoyed having coffee on the back veranda."
United States
Cher
The price is AU$221
includes taxes & fees
3 Dec - 4 Dec
Central Park Bed & Breakfast
Exterior
Homewood Suites by Hilton Louisville Downtown, KY

Homewood Suites by Hilton Louisville Downtown, KY

3.0 star property
Downtown Louisville, 0.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (1009)
"Very good hotel, staff and location."
United States
Paul
The price is AU$180
includes taxes & fees
19 Dec - 20 Dec
Homewood Suites by Hilton Louisville Downtown, KY
Front of property
21c Museum Hotel Louisville

21c Museum Hotel Louisville

4.5 star property
Downtown Louisville, < 0.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1005)
" Loved our stay, would definitely plan to come back if we are ever in the area again."
United States
Erica
The price is AU$257
includes taxes & fees
1 Jan - 2 Jan 2026
21c Museum Hotel Louisville
Lobby
Towneplace Suites By Marriott Louisville Downtown

Towneplace Suites By Marriott Louisville Downtown

3.0 star property
Downtown Louisville, 0.3 km from Louisville Science Center
9.2 out of 10, Wonderful, (506)
"Great location"
United States
Tina
The price is AU$174
includes taxes & fees
15 Dec - 16 Dec
Towneplace Suites By Marriott Louisville Downtown
Sauna, body treatments, aromatherapy, hot stone massages
Omni Louisville Hotel

Omni Louisville Hotel

4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.2 out of 10, Wonderful, (1704)
"Wonderful property and staff. Would love to stay again. "
United States
Hanna
The price is AU$300
includes taxes & fees
1 Jan - 2 Jan 2026
Omni Louisville Hotel
Bar (on property)
Moxy Louisville Downtown

Moxy Louisville Downtown

3.5 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.2 out of 10, Wonderful, (691)
"Great staff, location, and atmosphere. "
United States
Haley
The price is AU$212
includes taxes & fees
7 Dec - 8 Dec
Moxy Louisville Downtown
Property amenity
AC Hotel Louisville Downtown

AC Hotel Louisville Downtown

3.5 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (594)
"Location is great. Fun neighborhood to explore. Nulu! "
United States
Brenda
The price is AU$176
includes taxes & fees
27 Dec - 28 Dec
AC Hotel Louisville Downtown
View from property
TownePlace Suites by Marriott Louisville North

TownePlace Suites by Marriott Louisville North

3.0 star property
2.2 km from Louisville Science Center
9.2 out of 10, Wonderful, (635)
"I would definitely stay here again if in the area. Nice rooms and we'll run hotel."
United States
Ryan
The price is AU$174
includes taxes & fees
21 Dec - 22 Dec
TownePlace Suites by Marriott Louisville North
Hypo-allergenic bedding, in-room safe, desk, laptop workspace
Hotel Genevieve part of JdV by Hyatt

Hotel Genevieve part of JdV by Hyatt

4.0 star property
East Market District, 2.1 km from Louisville Science Center
9.2 out of 10, Wonderful, (1011)
"Great stay"
United States
Katharine
The price is AU$243
includes taxes & fees
3 Dec - 4 Dec
Hotel Genevieve part of JdV by Hyatt
4 restaurants, breakfast, lunch, dinner served; American cuisine
Galt House Hotel Trademark Collection by Wyndham

Galt House Hotel Trademark Collection by Wyndham

4.0 star property
Downtown Louisville, 0.5 km from Louisville Science Center
9.0 out of 10, Wonderful, (3830)
"Great place to stay "
United States
Tia
The price is AU$168
includes taxes & fees
10 Dec - 11 Dec
Galt House Hotel Trademark Collection by Wyndham
Dinner served
Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

4.0 star property
Downtown Louisville, 0.8 km from Louisville Science Center
9.0 out of 10, Wonderful, (1098)
"Clean, hotel was amazing, great breakfast "
United States
Alana
The price is AU$214
includes taxes & fees
17 Dec - 18 Dec
Embassy Suites Louisville Downtown
View from room
Aloft Louisville Downtown

Aloft Louisville Downtown

3.0 star property
Downtown Louisville, 0.9 km from Louisville Science Center
9.0 out of 10, Wonderful, (1004)
"The first night our lock on our door stopped working, so we were locked out. They were very accommodating to get us a different room for the evening and got us whatever we needed! Very nice place to stay downtown!"
United States
Chris
The price is AU$197
includes taxes & fees
19 Dec - 20 Dec
Aloft Louisville Downtown
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Louisville Science Center Hotel Reviews

Embassy Suites Louisville Downtown

Embassy Suites Louisville Downtown

10/10 Excellent
"good all around"
THOMAS 3-night trip
Posted 2 days ago
Embassy Suites Louisville Downtown

Hotels near other Louisville Science Center attractions

Exploration of Louisville Slugger Museum in Downtown Louisville, Kentucky on a Sunny Day

Louisville Slugger Museum

4.5/5 (1,200 reviews)
Baseball is part of the American fabric. See where one important tool for this sport is produced in the factory that makes ball games possible.
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A great stop! This has to be one of the best museums I’ve been about somebody! Great stop and a fantastic life!
Photo by Corey Dargan
Open Photo by Corey Dargan

Muhammad Ali Center

4.3/5 (298 reviews)
One of the world’s greatest boxers continues providing inspiration beyond the world of sport. Understand this superstar by visiting this center honoring him.
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Frequently asked questions

What's the area like around Louisville Science Center?
Louisville Science Center is located in an area of Louisville known for its stunning river views, sporting events and great live music scene. If you're looking for a convenient place to stay, take a look at the 289 hotels and other accommodation options you'll find within a mile.
Where is the best place to stay near Louisville Science Center?
Adjacent to Louisville Science Center, Holiday Inn Express & Suites Louisville Downtown by IHG is one of the top choices for your stay based on our traveller data, and this hotel offers free breakfast and a 24-hour fitness centre. Other good choices within a short distance include Galt House Hotel Trademark Collection by Wyndham and Omni Louisville Hotel.
How many hotels can I expect to find close to Louisville Science Center?
Expedia has 289 hotels and other accommodation options within a mile from Louisville Science Center.
If I need to cancel the hotel reservation for my stay near Louisville Science Center, will I receive a refund?
Yes! Most hotel room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If you booked a non-refundable reservation, you might be able to still cancel and get a refund within a 24-hour period of booking. Add dates, click "Search", then use the filter option "fully refundable" to get the top deals on offer near Louisville Science Center.
What can I see and do near Louisville Science Center?
21c Museum Hotel, Louisville Slugger Museum and Muhammad Ali Center feature a variety of fascinating exhibits to see while you're in town. Explore landmarks like Belle of Louisville, Whiskey Row and Big Four Bridge. You can catch a show at Kentucky Center for the Performing Arts, Louisville Palace and Derby Dinner Playhouse.