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21c Museum Hotel Louisville

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Luxury
4.5 star property
9.4

Exceptional

Luxury boutique hotel near Louisville Slugger Museum

Close to Kentucky International Convention Center and KFC Yum Center, 21c Museum Hotel Louisville provides dry cleaning/laundry services, a bar and a 24-hour gym. Treat yourself to a Swedish massage at 21c Spa, the on-site spa. The on-site restaurant, Proof on Main, offers breakfast, brunch, lunch and dinner. In addition to a 24-hour business centre, guests can connect to free in-room WiFi.

Popular amenities

  • Spa
  • Pet-friendly
  • Free Wi-Fi
  • Air-conditioning
  • Gym
The current price is AU$252
includes taxes & fees
25 May - 26 May

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About this property

21c Museum Hotel Louisville

  • Luxury boutique hotel near Louisville Slugger Museum
  • Close to Kentucky International Convention Center and KFC Yum Center, 21c Museum Hotel Louisville provides dry cleaning/laundry services, a bar and a 24-hour gym. Treat yourself to a Swedish massage at 21c Spa, the on-site spa. The on-site restaurant, Proof on Main, offers breakfast, brunch, lunch and dinner. In addition to a 24-hour business centre, guests can connect to free in-room WiFi.
  • You'll also enjoy perks such as:
    • Limo/town car service, full breakfast (surcharge) and valet parking (surcharge)
    • An electric car charging station, a 24-hour front desk and a lift
    • Luggage storage, smoke-free property and a front desk safe
    • Guest reviews say great things about the dining options, helpful staff and location
  • Room features
  • All 91 rooms include comforts, such as premium bedding and laptop-compatible safes, in addition to perks, such as laptop-friendly workspaces and air conditioning. Guest reviews speak positively of the cleanliness rooms at the property.
  • More conveniences in all rooms include:
    • LED light bulbs and eco-friendly cleaning products
    • Bathrooms with designer toiletries and hairdryers
    • 50-inch HDTVs with premium channels
    • Wardrobes/cupboards, free infant beds and daily housekeeping

Awards and affiliations

  • Eco-certified property
  • This property participates in Green Key Global – a program that measures the property's impact on one or more of the following: environment, community, cultural-heritage, the local economy.

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Policies

Check-in

Check-in start time: 4 PM; check-in end time: midnight

Contactless check-in and check-out are available

Minimum check-in age - 21

Check-out

Check-out before 11 AM

Contactless check-out

Special check-in instructions

Front desk staff will greet guests on arrival at the property

Information provided by the property may be translated using automated translation tools

Access methods

Staffed front desk

Pets

Pets are allowed for an extra charge of USD 40.00 per accommodation, per stay

Service animals are welcome, and are exempt from fees

Up to 23 kg per pet

Food and water bowls are available

Children and extra beds

Children are welcome

Rollaway/extra beds are available for USD 30.0 per night.

Free cots are available on request at the property

Payment types

Important information

Fees

You'll be asked to pay the following charges at the property. Fees may include applicable taxes:

  • Service fee: USD 5.00 per accommodation, per stay

We have included all charges provided to us by the property.

Optional extras

  • Fee for full breakfast: approximately USD 5 to 25 per person
  • Valet parking fee: USD 32 per night (in/out privileges)
  • Pet fee: USD 40.00 per accommodation, per stay
  • Service animals are exempt from fees
  • Rollaway bed fee: USD 30.0 per night

The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.

You need to know

Extra-person charges may apply and vary depending on property policy
Government-issued photo identification and a credit card may be required at check-in for incidental charges
Special requests are subject to availability upon check-in and may incur additional charges; special requests cannot be guaranteed
The name on the credit card used at check-in to pay for incidentals must be the primary name on the guestroom reservation
This property accepts credit cards; cash is not accepted
Safety features at this property include a carbon monoxide detector, a fire extinguisher, a smoke detector, a security system, a first aid kit and window guards
This property affirms that it follows the cleaning and disinfection practices of ALLSAFE (Accor Hotels)

We should mention

Reservations are required for massage services; reservations can be made by contacting the property prior to arrival, using the contact information on the booking confirmation
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation
This property welcomes guests of all sexual orientations and gender identities (LGBTQ+ friendly)

Frequently asked questions

Is 21c Museum Hotel Louisville pet-friendly?

Yes, this hotel allows pets with a maximum weight of up to 23 kg per pet. There's a fee of USD 40.00 per accommodation, per stay. Service animals are exempt from fees.

How much does it cost to stay at 21c Museum Hotel Louisville?

As of 22 May 2026, prices found for a 1-night stay for 2 adults at 21c Museum Hotel Louisville on 25 May 2026 start from AU$252, including taxes and fees. This price is based on the lowest nightly price found in the last 24 hours for stays in the next 30 days. Prices are subject to change. Choose your dates for more accurate prices.

How much is parking at 21c Museum Hotel Louisville?

Valet parking is available for USD 32 per night.

What time is check-in at 21c Museum Hotel Louisville?

Check-in start time: 4 PM; check-in end time: midnight.

What time is check-out at 21c Museum Hotel Louisville?

Checkout is at 11 AM.

Where is 21c Museum Hotel Louisville located?

Located in Downtown Louisville, this luxury hotel is steps away from Ohio River Valley and Louisville Slugger Museum. Kentucky International Convention Center and KFC Yum Center are also within 15 minutes.

Can I cancel my reservation for free and receive a full refund?

Yes, this property offers free cancellation on selected room rates because flexibility matters! Please refer to the property cancellation policy on our site for more details about any exclusions or requirements.

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Reviews

Reviews

9.4

Exceptional

9.6

Cleanliness

9.0

Amenities

9.4

Staff & service

9.6

Property conditions & facilities
Rating 10 - Excellent. 773 out of 1002 reviews
Rating 8 - Good. 129 out of 1002 reviews
Rating 6 - Okay. 62 out of 1002 reviews
Rating 4 - Poor. 20 out of 1002 reviews
Rating 2 - Terrible. 18 out of 1002 reviews

Reviews

Verified

10/10 Excellent

Jason

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Unique venue with some many amenities. Staff are super helpful and hospital. Will stay again when I’m in town.
Stayed 1 night in Apr 2026
Verified

10/10 Excellent

Brent

Liked: Cleanliness, amenities, property conditions & facilities
Nice room and close to all the distilleries. Great restaurant on site as well!
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Tamara

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21C is by far the best hotel we’ve ever stayed in. The museum is fantastic! The entire Staff went above and beyond for us.
Stayed 1 night in Apr 2026
Verified

6/10 Okay

Regina

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Room was clean, location was good. Homeless people sleeping right outside of the doorway doesn’t give the hotel the best vibe. Restaurant on site was just okay. Walls are pretty thin.
Stayed 2 nights in Apr 2026
Verified

10/10 Excellent

Amanada

Liked: Cleanliness, amenities, property conditions & facilities
Large spacious room and super comfortable bed Fascinating art and super bar and restaurant too Great service from all staff
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

MARC

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
The rooms and staff were great and the penguins were alive.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Rachel

Liked: Cleanliness, amenities, property conditions & facilities
Great room, super kind staff
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Michael

Interesting Ambiente, very knowledgeable and friendly staff, great bar and good food in the restaurant with special choices.
Stayed 2 nights in Feb 2026
Verified

10/10 Excellent

Susan

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Very clean. A unique experience.
Stayed 3 nights in Apr 2026
Verified

10/10 Excellent

Jeannie

Liked: Cleanliness, amenities, property conditions & facilities
Clean room, art work is beautiful, friendly staff .
Stayed 1 night in Jan 2026
Verified

8/10 Good

Stacy

Liked: Cleanliness, amenities, property conditions & facilities
Great location for Whiskey Row in Downtown Louisville. Hotel was clean, artsy and has a great restaurant on site.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Lorie

Liked: Cleanliness, staff & service, amenities
All the staff were great! The rooms were clean the coffee was great. I would stay here again.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

Tammy

Liked: Cleanliness, amenities, property conditions & facilities
Staff was very kind, the art was fantastic, location was perfect to explore Whiskey Row, and we had a gorgeous room. Loved our time away there!
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

Barbara

Liked: Cleanliness, amenities, property conditions & facilities
Staff very helpful. Rooms are spacious and clean. Lobby exhibits unique and interesting. Hotel well situated in downtown to access popular tourist attractions. Enjoyed our stay.
Stayed 3 nights in Jan 2026
Verified

8/10 Good

Tamara

Liked: Cleanliness, amenities, property conditions & facilities
Room was clean. The staff is helpful, nice, welcoming. Loved the art. Room is large. Great area.
Stayed 1 night in Feb 2026
Verified

10/10 Excellent

Lee Anne

Liked: Cleanliness, amenities, property conditions & facilities
Really interesting setting for a hotel with all of the artwork. The room was clean and comfortable. We would have appreciated softer towels.
Stayed 2 nights in Jan 2026
Verified

10/10 Excellent

david

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Beautiful environment Helpful friendly staff
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, property conditions & facilities
Room was very clean and staff were very friendly.
Stayed 1 night in Sep 2025
Verified

10/10 Excellent

Clark and Margaret

Liked: Cleanliness, amenities, property conditions & facilities
Room clean , comfortable and quiet.
Stayed 1 night in Nov 2025
Verified

10/10 Excellent

Jennifer

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Amazing location and great hotel. Staff was great. Restaurant was delicious. Great location on Main Street!!
Stayed 4 nights in Sep 2025
Verified

10/10 Excellent

Robin

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
21c Museum Hotel is a fun and unique experience. Beautiful rooms and centrally located to shops, restaurants and distilleries in Louisville.
Stayed 2 nights in Oct 2025
Verified

10/10 Excellent

Kevin

Liked: Cleanliness, staff & service, amenities
The room was great! The bar was fantastic. The hotel accommodated all of my requests. My husband and I have stayed here a few times. I'm truly grateful for the kindness of the staff.
Stayed 1 night in Dec 2025
Verified

10/10 Excellent

earl

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Perfect location for walking Louisville
Stayed 4 nights in Oct 2025
Verified

10/10 Excellent

Ilya

Liked: Cleanliness, staff & service, property conditions & facilities, room comfort
Great location, comfy beds, great service
Stayed 2 nights in Jun 2025
Verified

10/10 Excellent

DONALD

Liked: Cleanliness, staff & service, amenities, property conditions & facilities
Attractive, comfortable rooms are as nice as any in the downtown area. On Museum Row, close to Lou Slugger Museum, Frazier History Museum. 10 min. walk to Bourbon Row. On site rest. very good, but pricy. Would definitely stay again. Ten, of course!
Stayed 2 nights in Jan 2026