South Main Travel Guide
Tourist Guide
Visit South Main
Popular places to visit
NRG Stadium
Catch an event at NRG Stadium during your trip to Houston. Attend a sporting event or simply enjoy the top-notch restaurants while you're in the area.
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the great live music and acclaimed art galleries in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the lively festivals and acclaimed theatre scene in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and acclaimed art galleries in this vibrant area.
Rice University
Enjoy the student vibe when you visit Rice University during your travels in Houston. Experience the area's lively festivals and acclaimed theatre scene.
Activities
Space Center Houston Admission Ticket
NASA's Space Center Admission Plus Houston City Tour
Houston: Houston Botanic Garden Entry Ticket
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston Museum of Natural Science: Butterfly Center Ticket
Houston: Holocaust Museum Houston Entry Ticket
Our pick of the best South Main Hotel Deals
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Staff was great!
Reviewed on 13 Feb 2026
Blossom Hotel Houston, Curio Collection by Hilton
Excellent hotel and restaurant!
Reviewed on 11 Feb 2026
Hotel Zaza Houston Museum District
Compared to Memorial District, the Museum District was up to par in terms of the art & area. Will definitely stay here again if I am in the area.
Reviewed on 5 Feb 2026
The Whitehall Houston
Hotel lobby was really nice, staff warm and inviting. Rooms need updating however, clean for the most part. Location was great! Within walking distance to Houston Rockets games. We caught a game the night we flew in walked right to the arena didn't have to worry about traffic, parking or uber cost. ...
Reviewed on 10 Feb 2026
The Royal Sonesta Houston Galleria
Always an excellent stay at The Royal Sonesta. Great place to stay near the Galleria area in Houston. I went for work. Breakfast buffet does need improvement. Bar menu has good menu and extra large portions. I will definitely return.
Reviewed on 11 Feb 2026
La Quinta Inn & Suites by Wyndham Houston Bush IAH South
The room was clean and quiet. The bed was quite comfortable. Easy check in and check out service. Good shuttle service.
Reviewed on 13 Feb 2026
Other neighbourhoods around South Main
Astrodome
While you're in Astrodome, take in top sights like NRG Stadium or NRG Arena, and hop on the metro to see more of the city at Stadium Park/Astrodome Station or Smith Lands Station.
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Museum District. Top attractions like Children's Museum of Houston and Houston Natural Science Museum are major draws, and you can catch the metro at Museum District Station or Hermann Park/Rice U Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Children's Museum of Houston or Houston Natural Science Museum and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Rothko Chapel or Menil Collection while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
