Visit South Main
Popular places to visit
George R. Brown Convention Center
During your trip, find out what's happening in George R. Brown Convention Center, a top convention centre in Houston. Experience the acclaimed theatre scene and entertainment choices in this vibrant area.
NASA Johnson Space Center
After visiting NASA Johnson Space Center, make a plan to see the other sights and activities in Houston. Amble around the area's lakeside or attend a sporting event.
Daikin Park
Catch an event at Daikin Park during your trip to Houston. Experience the entertainment choices and great live music in this vibrant area.
Toyota Center
Catch an event at Toyota Center during your trip to Houston. Experience the entertainment choices and lively festivals in this vibrant area.
Rice University
Walk around the campus of Rice University, a top university in Houston. Experience the area's acclaimed theatre scene and fascinating museums.
University of Houston
Walk around the campus of University of Houston, a top university in Houston. Experience the great live music and lively festivals in this vibrant area.
Activities
Space Center Houston Admission Ticket
Houston Museum of Natural Sciences: Planetarium Ticket
Astroville Tunnel Tour of Downtown Houston (Air-Conditioned)
Houston: Guided City Tour by an Open-Top Double Decker Bus
Houston: Houston Botanic Garden Entry Ticket
Houston Museum of Natural Science General Admission Ticket
Our pick of the best South Main Hotel Deals
DoubleTree by Hilton Hotel & Suites Houston by the Galleria
Reviewed on 18 Oct 2025
Club Quarters Hotel Downtown, Houston
Reviewed on 16 Oct 2025
Hotel Zaza Houston Museum District
Reviewed on 18 Oct 2025
Magnolia Hotel Houston, A Tribute Portfolio Hotel
Reviewed on 18 Oct 2025
DoubleTree by Hilton Hotel Houston - Greenway Plaza
Reviewed on 18 Oct 2025
Crowne Plaza Houston Med Ctr-Galleria Area by IHG
Reviewed on 18 Oct 2025
Other neighbourhoods around South Main
Texas Medical Center
Well liked for its restaurants, museums and shopping, there's plenty to explore in Texas Medical Center. Attractions like Houston Zoo are a major draw, and you can hop on the metro at TMC Transit Center or Dryden/TMC Station to see more of the city.
Houston Museum District
Known for its abundant dining options and interesting museums, there's plenty to explore in Houston Museum District. Top attractions like Houston Zoo and Children's Museum of Houston are major draws, and you can catch the metro at M. D. Anderson Station or Museum District Station to see more of the city.
South Central Houston
If you're spending time in South Central Houston, check out sights like Houston Zoo or Continental Club and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
Montrose
Unique features of Montrose include the theatres and museums. Make a stop by Menil Collection or Houston Center for Photography while you're exploring the area.
River Oaks
Gardens and monuments are just a few things travellers like about River Oaks. A stop by River Oaks Country Club is also recommended if you've got time to explore the area.
Greater Third Ward
If you're spending time in Greater Third Ward, check out sights like TDECU Stadium or Eldorado Ballroom and hop on the metro to see more of the city at Elgin/Third Ward Station or TSU/UH Athletics District Station.
