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Top hotels and accommodation in Depew

Comfort Inn & Suites Niagara Falls Blvd USA

2.5 star property
La Salle
8.8 out of 10, Excellent, (1397)
"Friendly staff, hotel was clean."
United States
Gail
Travelling for leisure
The price is AU$125
includes taxes & fees
12 Dec - 13 Dec
Comfort Inn & Suites Niagara Falls Blvd USA

Holiday Inn Express Grand Island - Niagara Falls by IHG

2.5 star property
Grand Island
8.8 out of 10, Excellent, (1589)
"Nice clean room and the front desk staff was very nice."
United States
Diana
Travelling with partner
The price is AU$119
includes taxes & fees
4 Jan - 5 Jan 2026
Holiday Inn Express Grand Island - Niagara Falls by IHG

Hampton Inn East Aurora

2.5 star property
East Aurora
9.4 out of 10, Exceptional, (970)
"Rooms were clean for the most part (hair in the shower. )"
United States
Amy
Travelling with partner
The price is AU$204
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn East Aurora

Sleep Inn & Suites Buffalo Airport

2.5 star property
Buffalo
8.0 out of 10, Very good, (1876)
"This hotel is very comfy , bedroom super clean"
United States
Julissa
The price is AU$123
includes taxes & fees
29 Dec - 30 Dec
Sleep Inn & Suites Buffalo Airport

Comfort Inn & Suites Hamburg - Buffalo South

2.5 star property
Hamburg
7.2 out of 10, Good, (1003)
"it was inexpensive and convenient to the location i was showing my horse"
United States
Patricia
Travelling solo
The price is AU$122
includes taxes & fees
19 Dec - 20 Dec
Comfort Inn & Suites Hamburg - Buffalo South

Red Roof Inn Buffalo - Niagara Airport

2.0 star property
Bowmansville
7.2 out of 10, Good, (1000)
"King size bed was very comfortable"
United States
Angie
The price is AU$96
includes taxes & fees
10 Dec - 11 Dec
Red Roof Inn Buffalo - Niagara Airport

Microtel Inn & Suites by Wyndham Niagara Falls

2.5 star property
Niagara Falls
8.2 out of 10, Very good, (1004)
"Very clean, beds and mattress was very good."
United States
Prashant
Travelling with small children
The price is AU$132
includes taxes & fees
8 Dec - 9 Dec
Microtel Inn & Suites by Wyndham Niagara Falls

La Quinta Inn & Suites by Wyndham Buffalo Amherst

3.0 star property
Buffalo
8.6 out of 10, Excellent, (1961)
"Hotel was clean and well maintained"
United States
Keith
Travelling solo
The price is AU$131
includes taxes & fees
30 Dec - 31 Dec
La Quinta Inn & Suites by Wyndham Buffalo Amherst

Motel 6 Amherst, NY - Buffalo

2.0 star property
Buffalo
6.4 out of 10, (1001)
"I was impressed by the cleanliness of the room."
United States
Gina
Travelling for leisure
The price is AU$85
includes taxes & fees
10 Dec - 11 Dec
Motel 6 Amherst, NY - Buffalo

Econo Lodge At The Falls North

2.0 star property
La Salle
7.8 out of 10, Good, (1120)
"The staff was friendly, rooms are clean an spacious."
United States
Richard
Travelling with friends
The price is AU$96
includes taxes & fees
4 Jan - 5 Jan 2026
Econo Lodge At The Falls North

CenterWay Hotel Tonawanda

2.0 star property
Tonawanda
7.8 out of 10, Good, (1003)
"Room was clean and owners friendly"
Canada
Laura
Travelling for leisure
The price is AU$103
includes taxes & fees
8 Dec - 9 Dec
CenterWay Hotel Tonawanda

Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

2.5 star property
Buffalo
8.2 out of 10, Very good, (1002)
"room was clean and smelled great"
United States
Marissa
The price is AU$142
includes taxes & fees
15 Dec - 16 Dec
Holiday Inn Express Hotel & Suites Buffalo-Airport by IHG

Hampton Inn Niagara Falls/Blvd

2.5 star property
La Salle
8.4 out of 10, Very good, (1000)
"the room was clean and close to the elevator"
Canada
Betty
Travelling with partner
The price is AU$128
includes taxes & fees
14 Dec - 15 Dec
Hampton Inn Niagara Falls/Blvd

Sleep Inn Amherst - Buffalo North near University

2.5 star property
Buffalo
8.8 out of 10, Excellent, (1140)
"The room was on the small side, but clean and nice looking."
United States
Shannon
Travelling for leisure
The price is AU$143
includes taxes & fees
30 Dec - 31 Dec
Sleep Inn Amherst - Buffalo North near University

Quality Inn Near Walden Galleria Mall

2.5 star property
Buffalo
8.0 out of 10, Very good, (1007)
"Clean room, comfortable beds and good water pressure!"
United States
Monica
Travelling with friends
The price is AU$144
includes taxes & fees
10 Dec - 11 Dec
Quality Inn Near Walden Galleria Mall

Best Western Summit Inn

2.5 star property
Niagara Falls
8.6 out of 10, Excellent, (1406)
"We enjoyed the pool and overall cleanliness of this property."
United States
Ken
Travelling with partner
The price is AU$137
includes taxes & fees
8 Dec - 9 Dec
Best Western Summit Inn

Comfort Inn University

2.5 star property
Buffalo
8.0 out of 10, Very good, (1198)
"The room was spotless, spacious, and very comfortable, with all the little details thought of."
United States
Lathania
Travelling for leisure
The price is AU$175
includes taxes & fees
22 Dec - 23 Dec
Comfort Inn University

La Quinta Inn by Wyndham Buffalo Airport

3.0 star property
Buffalo
8.0 out of 10, Very good, (1344)
"Clean room and very nice and helpful staff!"
United States
Michelle
Travelling with partner
The price is AU$131
includes taxes & fees
12 Dec - 13 Dec
La Quinta Inn by Wyndham Buffalo Airport

Spark by Hilton Lockport

3.0 star property
Lockport
7.4 out of 10, Good, (66)
"I love how Hilton has full size pump bottles in the shower now."
United States
Natalie
Travelling with partner
The price is AU$108
includes taxes & fees
14 Dec - 15 Dec
Spark by Hilton Lockport

Econo Lodge Darien Lakes

2.0 star property
Corfu
7.8 out of 10, Good, (803)
"Pros: Quiet, convienient, really comfy bed."
United States
Phil
Travelling with partner
The price is AU$120
includes taxes & fees
14 Dec - 15 Dec
Econo Lodge Darien Lakes
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Depew Hotel Reviews

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Frequently asked questions

What's the best place for a stay in Depew?
Located 8.6 mi (13.9 km) from the heart of Depew, Hyatt Regency Buffalo / Hotel and Conference Center is a top choice for your stay, based on our traveller data. Two other choices for your stay in the area are Garden Place Hotel and Buffalo Airport Hotel. See all available top hotels, or vacation rentals in Depew.
What are some of the best holiday rentals that Depew has to offer?
Cozy Buffalo Getaway – Minutes to Downtown & Bills Stadium: This holiday home rental outside of Depew has air conditioning and WiFi to help you feel perfectly comfortable in your new surroundings. Kitchen amenities include a fridge, a stovetop and a microwave. See all vacation rentals in Depew.
If I need to cancel my hotel reservation in Depew, will I receive a refund?
Yes! Most hotel reservations are fully refundable if you cancel prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your arrival date. If you have a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Depew.
What are some accommodation options with pools in Depew?
Hyatt Regency Buffalo / Hotel and Conference Center: Hotel located near KeyBank Center. Features complimentary wireless Internet access, an indoor pool and a 24-hour fitness centre. M Hotel Buffalo and Days Inn & Suites by Wyndham Niagara Falls/Buffalo are a couple of other choices that offer an on-site pool. View all hotels with pools in Depew.
What is staying in Depew like?
Visitors can enjoy all that Depew has to offer, including the shopping, restaurants and sporting events. Tourists can also enjoy so much more including its waterfalls. In Depew, there are 12 hotels and other accommodation options to choose from. Find out more about Depew.
What should I see while I'm in Depew?
Places to visit in the wider area include Holiday Twin Rinks, Walden Galleria Mall and Samuel's Grande Manor. You'll also find Glen Falls and Buffalo Central Terminal in the area. Take a look at what more there is to see and do in Expedia's Depew guide.
How can I get around Depew?
If you want to explore the larger area, hop on a train at Buffalo-Depew Station. If you want to venture out around the area, you may want a rental car in Depew for your journey.
What's the seasonal weather like in Depew?
The hottest months are usually July and August, with an average temperature of 20°C, while the coldest months are January and February, with an average of -1°C. The snowiest months in Depew are January, March, February and December, with each month seeing an average of 43 cm of snowfall.

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