Holiday Homes in Chesapeake & Ohio Canal Towpath

  • Change your mind

    Book hotels with free cancellation
  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
  • Be picky

    Search almost a million properties worldwide

Check prices for these dates

In two weeks
In two months
In three months
In four months

Our top choices for Chesapeake & Ohio Canal Towpath holiday homes

10.0 out of 10, Exceptional, (39 reviews)
"Host was very responsive. Dog friendly space with adorable fire place, large TV and comfy sitting area. "
United States
Jess P.
The price is AU$241
includes taxes & fees
8 Mar - 9 Mar
Spacious 1 BR Modern Basement Suite near GMU w/private entry - Updated Amenities

Holiday Home in Alexandria

MOUNT VERNON RETREAT 🌸
9.8 out of 10, Exceptional, (129 reviews)
"This cozy apartment was a perfect place to stay. The quiet neighborhood is good for walks and near Mount Vernon."
United States
Pat M.
The price is AU$327
includes taxes & fees
21 Mar - 22 Mar
MOUNT VERNON RETREAT 🌸

Holiday Home in Oldtown

Oldtown Guesthouse
10.0 out of 10, Exceptional, (30 reviews)
"This was a wonderful place clean, private, spacious and convenient will definitely recomend"
United States
Karen C.
The price is AU$265
includes taxes & fees
9 Mar - 10 Mar
Oldtown Guesthouse
9.2 out of 10, Wonderful, (14 reviews)
"Great place to stay. Very convenient to everything in the city."
United States
Stephen R.
The price is AU$296
includes taxes & fees
7 Mar - 8 Mar
KING-SIZE BED in Master Bedroom plus 2 SLEEPING SOFAS in LR - WHOLE SUITE 64.
9.8 out of 10, Exceptional, (39 reviews)
"The coziest place with all the amenities! We absolutely loved our stay here and found it so relaxing. "
United States
Kelsey L.
The price is AU$319
includes taxes & fees
8 Mar - 9 Mar
Private Apt 1 Bedroom Hi-Speed Internet, DC Metro.
9.4 out of 10, Exceptional, (24 reviews)
"Great place... "
United States
Dennis N.
The price is AU$348
includes taxes & fees
8 Mar - 9 Mar
Fairfax-GMU 2BR Retreat - Fire Pit & Wooded Views

Holiday Home in Downtown Frederick

*Luxury Condo In Downtown Frederick*
9.0 out of 10, Wonderful, (77 reviews)
"Lovely place. It was perfect for our girls' trip long weekend. The rooms were so spacious and tastefully decorated. It was also super clean and had everything we needed, including for our night staying in with Door-dash to binge watch a couple Netflix series. The coffee lover in our group was so appreciative of the supplies and setup. The location is fabulous for walking the Creek Park, or to dinning and shopping options. We're looking forward to making this our Christmas present to each other...
United States
Lynne
The price is AU$355
includes taxes & fees
11 Mar - 12 Mar
*Luxury Condo In Downtown Frederick*
10.0 out of 10, Exceptional, (33 reviews)
"Lovely property, really nicely furnished and clean. Brilliant location for lots of places locally and close enough to walk into Leesburg itself to get ice cream!"
United Kingdom
Rachael B.
The price is AU$439
includes taxes & fees
10 Mar - 11 Mar
Leesburg Hideaway- King Bed + Private Backyard

Holiday Home in Meyersdale

Right off the bike trail.
9.6 out of 10, Exceptional, (101 reviews)
"Our stay was great will be definitely coming back!"
United States
Donald M.
The price is AU$198
includes taxes & fees
7 Mar - 8 Mar
Right off the bike trail.

Holiday Home in Frederick

Newly constructed 6 bedroom home
10.0 out of 10, Exceptional, (14 reviews)
"Quiet and convenient stay in very comfortable house. Host was on top of every question and very helpful, answered questions immediately. Many thanks for a lovely stay."
United States
Janine S.
The price is AU$651
includes taxes & fees
8 Mar - 9 Mar
Newly constructed 6 bedroom home

Holiday Home in Arlington Mill

Lux 4BR House-Mins to DC-Free Parking
8.4 out of 10, Very good, (22 reviews)
"The place was perfectly fine. It was clean with plenty of towels, soap, laundry detergent, coffee etc… The communication was good. Beds were reasonably comfortable."
United States
Todd H.
The price is AU$565
includes taxes & fees
9 Mar - 10 Mar
Lux 4BR House-Mins to DC-Free Parking

Holiday Home in McLean

The Wooded Retreat
9.6 out of 10, Exceptional, (7 reviews)
"Great stay, clean and well decorated, quiet area, owner communicated well. Would consider staying here again."
United States
David M.
The price is AU$493
includes taxes & fees
19 Mar - 20 Mar
The Wooded Retreat
9.4 out of 10, Exceptional, (122 reviews)
"Great location — right on the Carroll Creek Walk and a stone’s throw from excellent restaurants and nice shops. "
United States
Darby R.
The price is AU$389
includes taxes & fees
23 Mar - 24 Mar
RETREAT on the CREEK - Businees Travelor or Weekend Getaway. HISTORIC DISTRICT.
9.8 out of 10, Exceptional, (60 reviews)
"The beds were incredibly comfortable. Great house. Great location. "
United States
Julie B.
The price is AU$344
includes taxes & fees
9 Mar - 10 Mar
Welcome to the Rusty Rose-Restored Farmhouse feel in the heart of Jefferson, MD

Holiday Home in Northeast

Cozy 2/1.5 Getaway in Lily Ponds
8.4 out of 10, Very good, (17 reviews)
"Quiet neighborhood. Quick drive to Metro Station. I have no complaints about the property! "
United States
Barry H.
The price is AU$377
includes taxes & fees
17 Mar - 18 Mar
Cozy 2/1.5 Getaway in Lily Ponds
10.0 out of 10, Exceptional, (142 reviews)
"Love the place will book again"
United States
WAYNE M.
The price is AU$438
includes taxes & fees
22 Mar - 23 Mar
Charming "Cream of the Crop" Cape ~❤️of Middletown
10.0 out of 10, Exceptional, (39 reviews)
"Everything was very clean and tidy, and very bright. The beds were extremely comfortable. Location was perfect and we really enjoyed having the backyard with a hot tub and a fire pit very relaxing."
United States
Donna C.
The price is AU$385
includes taxes & fees
17 Mar - 18 Mar
Gorgeous apt, pets, hot tub & fire pit, walk --> DT Frederick
9.4 out of 10, Exceptional, (22 reviews)
"The house was spacious, clean and well decorated. We enjoyed the older house ambiance with modern amenities at a reasonable price. "
United States
Kevin C.
The price is AU$358
includes taxes & fees
16 Mar - 17 Mar
Renovated Farmhouse located near the C and O Canal
7.6 out of 10, Good, (27 reviews)
"The inside was well done and clean. Even though the neighbors are close, they were quiet. My husband and I were able to relax in a comfortable setting."
United States
Melissa H.
The price is AU$507
includes taxes & fees
11 Mar - 12 Mar
Single Level, 3 Bedroom Home In Between Harper's Ferry & Casino.

Holiday Home in Berkeley Springs

Modern, family-friendly, nature packed getaway
9.0 out of 10, Wonderful, (23 reviews)
"Great house! We loved the fire pit outside and the beautiful interior. Host was very responsive and helpful! Would def stay here again. "
United States
Erika R.
The price is AU$377
includes taxes & fees
16 Mar - 17 Mar
Modern, family-friendly, nature packed getaway
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.
Save an average of 15% on thousands of hotels when you're signed in

Top Chesapeake & Ohio Canal Towpath Hotel Reviews

Find out more about Chesapeake & Ohio Canal Towpath

Chesapeake & Ohio Canal Towpath Holiday Homes information

Number of reviews
915
Accommodation
560 Holiday Homes
Lowest Price
AU$198
Highest Price
AU$651

Explore a world of travel with Expedia