Santee River Dam on Lake Marion, South Carolina, Aerial drone view of electric power lines

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Our top choices for Santee hotels

Fairfield Inn & Suites by Marriott Santee

Fairfield Inn & Suites by Marriott Santee
3.0 star property
Santee
9.8 out of 10, Exceptional, (1,012 reviews)
"Nice hotel stay, excellent staff and accommodations."
United States
Carl
The price is AU$212
includes taxes & fees
24 June - 25 June
Fairfield Inn & Suites by Marriott Santee

Hampton Inn Santee-I-95

Hampton Inn Santee-I-95
2.5 star property
Santee
9.6 out of 10, Exceptional, (1,006 reviews)
"Nice breakfast, rooms spacious, convenient location"
United States
Gloria
The price is AU$210
includes taxes & fees
17 June - 18 June
Hampton Inn Santee-I-95

Tru By Hilton Santee

Tru By Hilton Santee
2.5 star property
Santee
9.2 out of 10, Wonderful, (852 reviews)
"Great bed and breakfast. Didn’t realize until after we purchased dinner outside the hotel that there was a small food court for sandwiches, snacks etc"
United States
Marie
The price is AU$168
includes taxes & fees
6 July - 7 July
Tru By Hilton Santee

Best Western Plus Santee Inn

Best Western Plus Santee Inn
2.5 star property
Santee
8.8 out of 10, Excellent, (1,007 reviews)
"Great breakfast bar - beautiful location in golf course and easy parking. "
United States
Nicole
The price is AU$174
includes taxes & fees
21 June - 22 June
Best Western Plus Santee Inn

Comfort Inn & Suites Santee

Comfort Inn & Suites Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,010 reviews)
"This property is right off the interstate with no traffic. The staff was very friendly and the hotel was clean. Breakfast and coffee were delicious. Highly recommend "
United States
Kimberley
The price is AU$165
includes taxes & fees
14 June - 15 June
Comfort Inn & Suites Santee

Holiday Inn Santee by IHG

Holiday Inn Santee by IHG
3.0 star property
Santee
8.2 out of 10, Very good, (1,000 reviews)
"Room was super clean and nice. Convenient location off of 95 and near Santee state park. Only minor complaint is the pool wasn't heated as stated. "
United States
Stefanie
The price is AU$157
includes taxes & fees
21 June - 22 June
Holiday Inn Santee by IHG

Baymont by Wyndham Santee

Baymont by Wyndham Santee
2.5 star property
Santee
8.0 out of 10, Very good, (1,464 reviews)
"Great overnight stop"
United States
Gary
The price is AU$119
includes taxes & fees
14 June - 15 June
Baymont by Wyndham Santee

Super 8 by Wyndham Santee/I-95

Super 8 by Wyndham Santee/I-95
2.0 star property
Santee
6.8 out of 10, (467 reviews)
"Ok hotel when money is tight. Only stayed one night but the room was clean and the beds were pretty comfy."
United States
Christalyn
The price is AU$101
includes taxes & fees
24 June - 25 June
Super 8 by Wyndham Santee/I-95

Travelodge by Wyndham Santee

Travelodge by Wyndham Santee
2.0 star property
Santee
7.2 out of 10, Good, (739 reviews)
"Staff was very friendly. "
United States
Sriram
The price is AU$98
includes taxes & fees
12 July - 13 July
Travelodge by Wyndham Santee

Quality Inn & Suites Santee I-95

Quality Inn & Suites Santee I-95
2.5 star property
Santee
6.0 out of 10, (538 reviews)
"Rooms are clean and staff was super nice and accommodating "
United States
Will
The price is AU$96
includes taxes & fees
6 July - 7 July
Quality Inn & Suites Santee I-95

Ramada by Wyndham Santee I-95

Ramada by Wyndham Santee I-95
2.0 star property
Santee
6.4 out of 10, (564 reviews)
"The room was very clean, the staff very friendly, and the restaurant/bar had good food and drinks and the pool tables added a unique touch!"
United States
Phyllis
The price is AU$114
includes taxes & fees
7 July - 8 July
Ramada by Wyndham Santee I-95

Red Roof Inn Santee

Red Roof Inn Santee
2.0 star property
Santee
6.6 out of 10, (655 reviews)
"Yes, great room."
United States
Gerald
The price is AU$100
includes taxes & fees
16 June - 17 June
Red Roof Inn Santee

Econo Lodge Santee

Econo Lodge Santee
2.0 star property
Santee
6.4 out of 10, (314 reviews)
"Very clean room, fast staff, a lot of food spots nearby! "
United States
Santiana
The price is AU$101
includes taxes & fees
5 July - 6 July
Econo Lodge Santee

Hampton Inn & Suites Orangeburg

Hampton Inn & Suites Orangeburg
2.5 star property
Orangeburg
9.4 out of 10, Exceptional, (806 reviews)
"The stay was great."
United States
Brandon
The price is AU$209
includes taxes & fees
6 July - 7 July
Hampton Inn & Suites Orangeburg

Fairfield Inn by Marriott Orangeburg

Fairfield Inn by Marriott Orangeburg
3.0 star property
Orangeburg
8.4 out of 10, Very good, (782 reviews)
"Great stay!!"
United States
Laylany
The price is AU$184
includes taxes & fees
30 June - 1 July
Fairfield Inn by Marriott Orangeburg

Tru by Hilton Orangeburg

Tru by Hilton Orangeburg
2.5 star property
Orangeburg
9.2 out of 10, Wonderful, (1,013 reviews)
"Excellent place to stay"
United States
Bartolo
The price is AU$203
includes taxes & fees
2 July - 3 July
Tru by Hilton Orangeburg

Doyles B and B at Players course LLC

Doyles B and B at Players course LLC
3.5 star property
Manning
The price is AU$274
includes taxes & fees
16 June - 17 June
Doyles B and B at Players course LLC

SpringHill Suites by Marriott Orangeburg

SpringHill Suites by Marriott Orangeburg
2.5 star property
Orangeburg
8.8 out of 10, Excellent, (766 reviews)
"Great location, spacious rooms, amazing breakfast."
United States
Pamela
The price is AU$204
includes taxes & fees
15 June - 16 June
SpringHill Suites by Marriott Orangeburg

Sunset Inn Manning I 95

Sunset Inn Manning I 95
2.0 star property
Summerton
4.8 out of 10, (55 reviews)
"Ok good value"
United States
William
The price is AU$80
includes taxes & fees
16 June - 17 June
Sunset Inn Manning I 95

Southern Lodge 601

Southern Lodge 601
Orangeburg
8.0 out of 10, Very good, (11 reviews)
"Clean and clear convenient"
United States
Christopher
The price is AU$110
includes taxes & fees
18 June - 19 June
Southern Lodge 601
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Stay near popular Santee attractions

Learn more about Santee

Nestled along Lake Marion, this charming town offers prime fishing and boating opportunities for outdoor enthusiasts. Visitors can tee off at Santee National Golf Club or explore nearby Santee State Park's hiking trails and campsites.

Cypress Trees with Spanish Moss growing on them. In Lake Marion at Santee State Park, Santee, Orangeburg County, South Carolina

Top Santee Hotel Reviews

More cheap accommodation in Santee

Frequently asked questions

Where is the best place for a stay in Santee?
Based on our traveller data, Baymont by Wyndham Santee is one of the top choices for your stay. This hotel offers free breakfast and free parking. Other good choices for your visit include Fairfield Inn & Suites by Marriott Santee and Tru By Hilton Santee. See all available top hotels, or vacation rentals in Santee.
What are some of the best holiday rentals that Santee has to offer?
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!: This highly rated holiday home rental in Santee is located on a lake, and has a patio, a selection of games and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a dishwasher, a fridge and a stovetop, so that you can cook with friends or family. Another good choice for your trip to Santee is Patio + Pool Table: Lake Marion Getaway. See all vacation rentals in Santee.
If I need to cancel my hotel reservation in Santee, will I receive a refund?
Yes, you'll find most room reservations are fully refundable as long as you cancel before the hotel's cancellation deadline, which is usually within 24-48 hours of check in. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santee.
What's the best place to stay on a budget in Santee?
Based on reviews, Baymont by Wyndham Santee is a popular hotel for our travellers who want a more economical choice, and features free breakfast and free Wi-Fi. View all budget hotels in Santee.
What's the best family accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Comfort Inn & Suites Santee is another good option for your stay with the kids. Find more child-friendly accommodations in Santee.
What is the top LGBTQ-friendly accommodation in Santee?
Fairfield Inn & Suites by Marriott Santee is a top LGBTQ-friendly hotel, and features free breakfast and free WiFi. Hampton Inn Santee-I-95 and Holiday Inn Santee by IHG are two other good choices for your trip. See all available hotels listed as LGBTQ-friendly in Santee.
What's the best dog-friendly hotel in Santee?
Baymont by Wyndham Santee is a top hotel for people travelling with their pets, and offers concierge services and free WiFi for its human guests. Two other good options for you and your pet include Best Western Plus Santee Inn and Tru By Hilton Santee. See more pet-friendly hotel accommodations in Santee.
What's the best accommodation for a golf trip to Santee?
Holiday Inn Santee by IHG is a top hotel that has an adjacent golf course and features free WiFi. Other good options to stay near a golf course include Ramada by Wyndham Santee I-95 and Super 8 by Wyndham Santee/I-95. Visit Santee Cooper Country Club or Santee National Golf Club to perfect your golf swing. See more golf hotels in Santee.
What are some accommodation options with pools in Santee?
Fairfield Inn & Suites by Marriott Santee is a top hotel with a pool, free buffet breakfast and free WiFi. Quality Inn & Suites Santee I-95 is an additional hotel with an on-site pool. View all hotels with pools in Santee.
What is staying in Santee like?
Families will find child-friendly activities in Santee, and visitors give high marks for the top-notch restaurants. This welcoming city also attracts tourists with its golf courses and cafes. In Santee, there are 118 hotels and other accommodation options to choose from. Find out more about Santee.
What are the top places to visit in Santee?
Favourite places to visit include Santee Cooper Country Club, Santee National Golf Club and Santee State Park. A couple of additional sights to add to your itinerary are Lake Marion and Santee Town Hall. Take a look at what more there is to see and do in Expedia's Santee guide.
What's the seasonal weather like in Santee?
The hottest months are usually July and August, with an average temperature of 26°C, while the coldest months are January and February, with an average of 11°C. Average annual precipitation for Santee is 1397 mm.

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