Cheap flights from Antofagasta Region

View AU$60 flight on Mon, 20 Oct 2025Opens in a new window

Popular airlines from Antofagasta Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Sky Airlines

    Sky Airlines

  • B & H Airlines

    B & H Airlines

  • Iberia

    Iberia

  • Delta

    Delta

  • American Airlines

    American Airlines

  • Qantas Airways

    Qantas Airways

    notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
    deals illustration

    Book smarter

    Save up to 35% on select hotels after you book a flight*
    trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Antofagasta Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Mon, 23 Mar - Tue, 31 Mar
CJC
Calama
SCL
Santiago
AU$137 Return, found 14 hours ago
AU$137
Return
found 14 hours ago
Select SKY AIRLINE flight, departing Mon, 23 Mar from Calama to Santiago, returning Tue, 31 Mar, priced at AU$137 found 14 hours ago
SKY AIRLINE
Mon, 23 Mar - Tue, 31 Mar
CJC
Calama
SCL
Santiago
AU$142 Return, found 14 hours ago
AU$142
Return
found 14 hours ago
Select SKY AIRLINE flight, departing Mon, 23 Mar from Calama to Santiago, returning Tue, 31 Mar, priced at AU$142 found 14 hours ago
SKY AIRLINE
Mon, 23 Mar - Tue, 31 Mar
CJC
Calama
SCL
Santiago
AU$152 Return, found 14 hours ago
AU$152
Return
found 14 hours ago
Select SKY AIRLINE flight, departing Mon, 23 Mar from Calama to Santiago, returning Tue, 31 Mar, priced at AU$152 found 14 hours ago
SKY AIRLINE
Tue, 18 Nov - Tue, 25 Nov
CJC
Calama
SCL
Santiago
AU$156 Return, found 1 day ago
AU$156
Return
found 1 day ago
Select SKY AIRLINE flight, departing Tue, 18 Nov from Calama to Santiago, returning Tue, 25 Nov, priced at AU$156 found 1 day ago
LATAM Airlines Group
Sun, 16 Nov - Sun, 23 Nov
CJC
Calama
SCL
Santiago
AU$158 Return, found 3 days ago
AU$158
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sun, 16 Nov from Calama to Santiago, returning Sun, 23 Nov, priced at AU$158 found 3 days ago
SKY AIRLINE
Fri, 31 Oct - Sun, 2 Nov
CJC
Calama
SCL
Santiago
AU$159 Return, found 5 days ago
AU$159
Return
found 5 days ago
Select SKY AIRLINE flight, departing Fri, 31 Oct from Calama to Santiago, returning Sun, 2 Nov, priced at AU$159 found 5 days ago
SKY AIRLINE
Mon, 23 Mar - Tue, 31 Mar
CJC
Calama
SCL
Santiago
AU$159 Return, found 14 hours ago
AU$159
Return
found 14 hours ago
Select SKY AIRLINE flight, departing Mon, 23 Mar from Calama to Santiago, returning Tue, 31 Mar, priced at AU$159 found 14 hours ago
SKY AIRLINE
Tue, 18 Nov - Tue, 25 Nov
CJC
Calama
SCL
Santiago
AU$160 Return, found 1 day ago
AU$160
Return
found 1 day ago
Select SKY AIRLINE flight, departing Tue, 18 Nov from Calama to Santiago, returning Tue, 25 Nov, priced at AU$160 found 1 day ago
SKY AIRLINE
Sun, 16 Nov - Sun, 23 Nov
CJC
Calama
SCL
Santiago
AU$161 Return, found 3 days ago
AU$161
Return
found 3 days ago
Select SKY AIRLINE flight, departing Sun, 16 Nov from Calama to Santiago, returning Sun, 23 Nov, priced at AU$161 found 3 days ago
SKY AIRLINE
Mon, 23 Mar - Tue, 31 Mar
CJC
Calama
SCL
Santiago
AU$165 Return, found 14 hours ago
AU$165
Return
found 14 hours ago
Select SKY AIRLINE flight, departing Mon, 23 Mar from Calama to Santiago, returning Tue, 31 Mar, priced at AU$165 found 14 hours ago

Explore a world of travel with Expedia

*Available to Expedia members.