
Antofagasta Region Holidays
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Your Antofagasta Region Holiday
Answer the call of adventure with a tailor-made holiday package to Antofagasta Region. Wherever your travels take you and whatever you plan to do, prepare to experience a destination that'll make you truly feel alive. The easiest way to organise your trip to Antofagasta Region is to begin with its most popular cities, which include San Pedro de Atacama, Antofagasta and Historical District. Expedia has flights, hotels, car rentals and more to help you organise your very own customised Antofagasta Region holiday today.
Top destinations in Antofagasta Region

San Pedro de Atacama

Calama
Antofagasta Region Essential Information
Language | Spanish |
|---|---|
Currency | Chilean pesos |
Local Welcome | ¡Hola! |
Local Goodbye | Adiós |
Closest Airport | Calama Airport (CJC) |
Population | 309,800 |
Top Sights | Valley of the Moon, Piedra del Coyote Overlook and Arco Iris Valley |
Our pick of the best Antofagasta Region Hotel Deals

Diego de Almagro San Pedro de Atacama
Toconao 460, San Pedro de Atacama, Antofagasta
Fully refundableReserve now, pay when you stay
The price is AU$161 per night from 27 Oct to 28 Oct
AU$161
27 Oct - 28 Oct
8/10 Very Good! (303 reviews)
The hotel is in an excellent location with the main pedestrian street half block away. Is a charming property but is quite old, don’t expect luxury or even high comfort (to an American standard), but to be fair, is quiet good compared with other hotels in the area. There are other more modern hotels ...
Reviewed on 23 Aug 2025

Noi Casa Atacama
Tocopilla E-8, San Pedro de Atacama, Antofagasta
The price is AU$484 per night from 28 Oct to 29 Oct
AU$484
28 Oct - 29 Oct
8.6/10 Excellent! (236 reviews)
Clean, quiet, good food and staff that are friendly and a pleasure to interact with. I loved visiting San Pedro and Noi Casa Atacama was part of the unforgettable experience, hope to visit again someday.
Reviewed on 1 Sept 2025

Hotel Cumbres San Pedro de Atacama
Avenida Las Chilcas S/N, Lote 10 Parcela 2, San Pedro de Atacama, Antofagasta
The price is AU$414 per night from 27 Oct to 28 Oct
AU$414
27 Oct - 28 Oct
8.8/10 Excellent! (462 reviews)
OMG this place was awesome. The food and staff were so incredible I never ate a meal in town because I was so excited to eat the high quality, beautiful food at this location. The staff were friendly and helpful. The rooms were impeccably clean. The outdoor private showers available in the rooms ...
Reviewed on 29 Sept 2025
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.











