Cheap flights from Antofagasta Region

View AU$64 flight on Sat, 24 Jan 2026Opens in a new window

Popular airlines from Antofagasta Region

  • LATAM Airlines Group

    LATAM Airlines Group

  • Sky Airlines

    Sky Airlines

  • B & H Airlines

    B & H Airlines

  • Iberia

    Iberia

  • American Airlines

    American Airlines

  • Delta

    Delta

  • notification illustration

    Be in the know

    Get alerts if flight prices drop or rise*
  • deals illustration

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • trophy illustration

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheapest flights from Antofagasta Region

These prices were available within the past 7 days. Prices quoted are per person, return, for the period specified. Prices and availability are subject to change. Additional terms apply.

SKY AIRLINE
Sun, 20 Sept - Sun, 11 Oct
CJC
Calama
SCL
Santiago
AU$156 Return, found 3 days ago
AU$156
Return
found 3 days ago
Select SKY AIRLINE flight, departing Sun, 20 Sept from Calama to Santiago, returning Sun, 11 Oct, priced at AU$156 found 3 days ago
SKY AIRLINE
Sun, 20 Sept - Sun, 11 Oct
CJC
Calama
SCL
Santiago
AU$158 Return, found 3 days ago
AU$158
Return
found 3 days ago
Select SKY AIRLINE flight, departing Sun, 20 Sept from Calama to Santiago, returning Sun, 11 Oct, priced at AU$158 found 3 days ago
LATAM Airlines Group
Sat, 24 Jan - Sun, 25 Jan
CJC
Calama
SCL
Santiago
AU$159 Return, found 3 days ago
AU$159
Return
found 3 days ago
Select LATAM Airlines Group flight, departing Sat, 24 Jan from Calama to Santiago, returning Sun, 25 Jan, priced at AU$159 found 3 days ago
SKY AIRLINE
Sun, 1 Feb - Sun, 8 Feb
CJC
Calama
SCL
Santiago
AU$160 Return, found 5 days ago
AU$160
Return
found 5 days ago
Select SKY AIRLINE flight, departing Sun, 1 Feb from Calama to Santiago, returning Sun, 8 Feb, priced at AU$160 found 5 days ago
SKY AIRLINE
Sat, 17 Jan - Sat, 24 Jan
CJC
Calama
SCL
Santiago
AU$165 Return, found 6 days ago
AU$165
Return
found 6 days ago
Select SKY AIRLINE flight, departing Sat, 17 Jan from Calama to Santiago, returning Sat, 24 Jan, priced at AU$165 found 6 days ago
SKY AIRLINE
Wed, 11 Feb - Wed, 11 Mar
CJC
Calama
SCL
Santiago
AU$167 Return, found 4 days ago
AU$167
Return
found 4 days ago
Select SKY AIRLINE flight, departing Wed, 11 Feb from Calama to Santiago, returning Wed, 11 Mar, priced at AU$167 found 4 days ago
SKY AIRLINE
Sun, 1 Feb - Sun, 8 Feb
CJC
Calama
SCL
Santiago
AU$168 Return, found 5 days ago
AU$168
Return
found 5 days ago
Select SKY AIRLINE flight, departing Sun, 1 Feb from Calama to Santiago, returning Sun, 8 Feb, priced at AU$168 found 5 days ago
SKY AIRLINE
Sun, 20 Sept - Sun, 11 Oct
CJC
Calama
SCL
Santiago
AU$170 Return, found 3 days ago
AU$170
Return
found 3 days ago
Select SKY AIRLINE flight, departing Sun, 20 Sept from Calama to Santiago, returning Sun, 11 Oct, priced at AU$170 found 3 days ago
LATAM Airlines Group
Sun, 1 Feb - Sun, 8 Feb
CJC
Calama
SCL
Santiago
AU$171 Return, found 5 days ago
AU$171
Return
found 5 days ago
Select LATAM Airlines Group flight, departing Sun, 1 Feb from Calama to Santiago, returning Sun, 8 Feb, priced at AU$171 found 5 days ago
LATAM Airlines Group
Wed, 11 Feb - Wed, 11 Mar
CJC
Calama
SCL
Santiago
AU$172 Return, found 4 days ago
AU$172
Return
found 4 days ago
Select LATAM Airlines Group flight, departing Wed, 11 Feb from Calama to Santiago, returning Wed, 11 Mar, priced at AU$172 found 4 days ago

Explore a world of travel with Expedia

*Available to Expedia members.