Cheap flights from Tampa to South Carolina Midlands

View AU$206 flight on Mon, 3 Nov. 2025Opens in a new window

Popular airlines from Tampa to South Carolina Midlands

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Tampa (TPA) to South Carolina Midlands (CAE)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Fri, 22 Aug. - Mon, 25 Aug.
TPA
Tampa
CLT
Charlotte
AU$247 Return, found 4 days ago
AU$247
Return
found 4 days ago
Select American Airlines flight, departing Fri, 22 Aug. from Tampa to Charlotte, returning Mon, 25 Aug., priced at AU$247 found 4 days ago
Delta
Fri, 22 Aug. - Mon, 25 Aug.
TPA
Tampa
CLT
Charlotte
AU$277 Return, found 4 days ago
AU$277
Return
found 4 days ago
Select Delta flight, departing Fri, 22 Aug. from Tampa to Charlotte, returning Mon, 25 Aug., priced at AU$277 found 4 days ago
American Airlines
Thu, 7 Aug. - Sun, 10 Aug.
TPA
Tampa
CLT
Charlotte
AU$353 Return, found 2 days ago
AU$353
Return
found 2 days ago
Select American Airlines flight, departing Thu, 7 Aug. from Tampa to Charlotte, returning Sun, 10 Aug., priced at AU$353 found 2 days ago
Delta
Thu, 7 Aug. - Sun, 10 Aug.
TPA
Tampa
CLT
Charlotte
AU$383 Return, found 2 days ago
AU$383
Return
found 2 days ago
Select Delta flight, departing Thu, 7 Aug. from Tampa to Charlotte, returning Sun, 10 Aug., priced at AU$383 found 2 days ago
American Airlines
Mon, 1 Sep. - Mon, 8 Sep.
TPA
Tampa
CLT
Charlotte
AU$430 Return, found 6 days ago
AU$430
Return
found 6 days ago
Select American Airlines flight, departing Mon, 1 Sep. from Tampa to Charlotte, returning Mon, 8 Sep., priced at AU$430 found 6 days ago
United
Thu, 27 Nov. - Mon, 1 Dec.
TPA
Tampa
CLT
Charlotte
AU$945 Return, found 10 hours ago
AU$945
Return
found 10 hours ago
Select United flight, departing Thu, 27 Nov. from Tampa to Charlotte, returning Mon, 1 Dec., priced at AU$945 found 10 hours ago

Find the cheapest month to fly from Tampa (TPA) to Columbia (CAE)

September is typically the cheapest month to fly

From AU$244 - AU$918 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.