Cheap flights from Des Moines to Rush Street

View AU$329 flight on Sat, 6 Sep. 2025Opens in a new window

Popular airlines from Des Moines to Rush Street

  • Jetstar

    Jetstar

  • Qantas Airways

    Qantas Airways

  • Virgin Australia

    Virgin Australia

  • Scoot

    Scoot

  • American Airlines

    American Airlines

  • Emirates

    Emirates

  • United

    United

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Des Moines (DSM) to Rush Street (CHI)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

American Airlines
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$290 Return, found 1 day ago
AU$290
Return
found 1 day ago
Select American Airlines flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$290 found 1 day ago
American Airlines
Tue, 2 Sep. - Tue, 9 Sep.
DSM
Des Moines
ORD
Chicago
AU$293 Return, found 5 days ago
AU$293
Return
found 5 days ago
Select American Airlines flight, departing Tue, 2 Sep. from Des Moines to Chicago, returning Tue, 9 Sep., priced at AU$293 found 5 days ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
MDW
Chicago
AU$320 Return, found 1 day ago
AU$320
Return
found 1 day ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$320 found 1 day ago
Delta
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$320 Return, found 1 day ago
AU$320
Return
found 1 day ago
Select Delta flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$320 found 1 day ago
Delta
Tue, 2 Sep. - Tue, 9 Sep.
DSM
Des Moines
ORD
Chicago
AU$323 Return, found 5 days ago
AU$323
Return
found 5 days ago
Select Delta flight, departing Tue, 2 Sep. from Des Moines to Chicago, returning Tue, 9 Sep., priced at AU$323 found 5 days ago
United
Sat, 6 Sep. - Sat, 13 Sep.
DSM
Des Moines
ORD
Chicago
AU$428 Return, found 1 day ago
AU$428
Return
found 1 day ago
Select United flight, departing Sat, 6 Sep. from Des Moines to Chicago, returning Sat, 13 Sep., priced at AU$428 found 1 day ago

Find the cheapest month to fly from Des Moines (DSM) to Chicago (ORD)

September is typically the cheapest month to fly

From AU$212 - AU$451 per traveller.

Graph displaying average flight prices per month

*Available to Expedia members.