Cheap flights from Orlando to Central San Diego

View AU$169 flight on Tue, 7 Oct. 2025Opens in a new window

Popular airlines from Orlando to Central San Diego

  • Spirit Airlines

    Spirit Airlines

  • Alaska Airlines

    Alaska Airlines

  • JetBlue Airways

    JetBlue Airways

  • United

    United

  • American Airlines

    American Airlines

  • Delta

    Delta

  • Southwest Airlines

    Southwest Airlines

  • Plan, book, fly with confidence

  • trending down icon

    Be in the know

    Get alerts if flight prices drop or rise*
  • bex rewards loyalty icon

    Book smarter

    Save up to 35% on select hotels after you book a flight*
  • payments icon

    Earn twice

    Earn your airline miles on top of our rewards
    Sign in

Cheap Flights from Orlando (ORL) to Central San Diego (SAN)

Prices were available within the past 7 days for one-way flights and round trip tickets for the period specified. Prices and availability are subject to change. Additional terms apply.

Alaska Airlines
Tue, 27 Jan. - Tue, 3 Feb.
MCO
Orlando
SAN
San Diego
AU$379 Return, found 4 days ago
AU$379
Return
found 4 days ago
Select Alaska Airlines flight, departing Tue, 27 Jan. from Orlando to San Diego, returning Tue, 3 Feb., priced at AU$379 found 4 days ago
Alaska Airlines
Wed, 1 Oct. - Sat, 11 Oct.
MCO
Orlando
SAN
San Diego
AU$383 Return, found 2 days ago
AU$383
Return
found 2 days ago
Select Alaska Airlines flight, departing Wed, 1 Oct. from Orlando to San Diego, returning Sat, 11 Oct., priced at AU$383 found 2 days ago
Delta
Tue, 27 Jan. - Tue, 3 Feb.
MCO
Orlando
SAN
San Diego
AU$394 Return, found 4 days ago
AU$394
Return
found 4 days ago
Select Delta flight, departing Tue, 27 Jan. from Orlando to San Diego, returning Tue, 3 Feb., priced at AU$394 found 4 days ago
Delta
Wed, 1 Oct. - Sat, 11 Oct.
MCO
Orlando
SAN
San Diego
AU$400 Return, found 2 days ago
AU$400
Return
found 2 days ago
Select Delta flight, departing Wed, 1 Oct. from Orlando to San Diego, returning Sat, 11 Oct., priced at AU$400 found 2 days ago
American Airlines
Tue, 27 Jan. - Tue, 3 Feb.
MCO
Orlando
CLD
Carlsbad
AU$411 Return, found 4 days ago
AU$411
Return
found 4 days ago
Select American Airlines flight, departing Tue, 27 Jan. from Orlando to Carlsbad, returning Tue, 3 Feb., priced at AU$411 found 4 days ago
United
Tue, 27 Jan. - Tue, 3 Feb.
MCO
Orlando
SAN
San Diego
AU$555 Return, found 4 days ago
AU$555
Return
found 4 days ago
Select United flight, departing Tue, 27 Jan. from Orlando to San Diego, returning Tue, 3 Feb., priced at AU$555 found 4 days ago
*Available to Expedia members.