Photo by Visit Greenville, South Carolina
Luxury Hotels & Resorts in Upstate South Carolina from AU$190
Change your mindBook hotels with free cancellation
Be pickySearch almost a million properties worldwide
Check availability on Upstate South Carolina Luxury Hotels
Our top choices for Upstate South Carolina luxury hotels
Grand Bohemian Lodge Greenville, Autograph Collection
Grand Bohemian Lodge Greenville, Autograph CollectionGreenville Downtown
9.6 out of 10, Exceptional, (492 reviews)
"The charm of the property is unmatched—beautifully designed spaces that feel both luxurious and intimate, with thoughtful details at every turn."
Ellina
The price is AU$441
includes taxes & fees
25 May - 26 May
9.8 out of 10, Exceptional, (797 reviews)
"Very comfortable and luxurious rooms."
Derin
The price is AU$251
includes taxes & fees
19 May - 20 May
9.8 out of 10, Exceptional, (718 reviews)
"Beautiful boutique property. Clean, quiet, & comfortable. Delicious breakfast and wonderful staff."
Jo
The price is AU$308
includes taxes & fees
1 June - 2 June
9.2 out of 10, Wonderful, (1,000 reviews)
- Historic luxury awaits in city centre Greenville, with pillowtop beds and attentive service at this architectural gem.
"Lovely classic hotel on Main Street, which is the place to be near Reedy Creek Falls, shopping and dining opportunities. Comfortable room, friendly staff and inexpensive self-parking. Wish we could stay longer."
Candy
The price is AU$292
includes taxes & fees
25 May - 26 May
10.0 out of 10, Exceptional, (88 reviews)
"Very comfortable and well-appointed room, deliciously crafted breakfasts and, most importantly, warmth and genuine care from the wonderful owners."
Sandra
The price is AU$217
includes taxes & fees
7 June - 8 June
9.6 out of 10, Exceptional, (599 reviews)
"Great location, beautiful, comfortable and very clean room!"
Mark
The price is AU$218
includes taxes & fees
19 May - 20 May
8.6 out of 10, Excellent, (651 reviews)
"Good location with restaurant and bar. Easy and comfortable public lounging areas."
Dewey
The price is AU$201
includes taxes & fees
24 May - 25 May
9.2 out of 10, Wonderful, (828 reviews)
"Ok this place was amazing, great view from room excellent amenities. Location could not of been any better! Only gripe was the internet went out on our 2nd day which was a inconvenience due to the TV was a ROKU which has to have internet to do anything. The water heater was small and ran out of hot water every use. The management gave us a $25 gift card for the internet being out. Overall it was a great stay !
"
Jai Anne
The price is AU$158
includes taxes & fees
31 May - 1 June
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Upstate South Carolina Hotel Reviews
Embassy Suites Greenville Golf Resort & Conference Center
10/10 Excellent
Explore a world of travel with Expedia
- Hotels near Bob Jones University
- Hotels near Bon Secours Wellness Arena
- Hotels near Donaldson Center
- Cheap Hotels in Easley
- Five Forks Hotels
- B&B in Golden Grove
- Caravan Parks in Golden Grove
- Holiday Homes in Golden Grove
- Cheap Hotels in Golden Grove
- Golden Grove Hotels
- Lgbt Welcoming Hotels in Green Avenue
- Apartments in Greenville
- B&B in Greenville
- Cottages in Greenville
- Hotels near Greenville Downtown
- Beach Hotels in Greenville Downtown
- Cheap Hotels in Greenville Downtown
- Luxury Hotels in Greenville Downtown
- Greenville Downtown Hotels
- Holiday Homes in Greenville
- Beach Hotels in Greenville
- Boutique Hotels in Greenville
- Cheap Hotels in Greenville
- Lgbt Welcoming Hotels in Greenville
- Luxury Hotels in Greenville
- Pet Friendly Hotels in Greenville
- Romantic Hotels in Greenville
- Greenville Hotels
- Motels in Greenville
- Cheap Hotels in Greenville - Spartanburg
- Greenville - Spartanburg Hotels
- Villas in Greenville
- Hotels near Heritage Park
- Mauldin Hotels
- Business Hotels in Northlake
- Cheap Hotels in Northlake
- Hotels with Parking in Northlake
- Lgbt Welcoming Hotels in Northlake
- Boutique Hotels in Piedmont
- Cheap Hotels in Piedmont
- Lgbt Welcoming Hotels in Piedmont
- Luxury Hotels in Piedmont
- Piedmont Hotels
- B&B in Sans Souci
- Holiday Homes in Sans Souci
- Cheap Hotels in Sans Souci
- Sans Souci Hotels
- Cheap Hotels in Southern Shops
- Hotels near Swamp Rabbit Trail
- Beach Hotels in Taylors
- Family Hotels in Taylors
- Hotels near The Peace Center
- Pet Friendly Hotels in Travelers Rest
- Caravan Parks in Welcome
- Welcome Hotels
- Cheap Hotels in West End
- Cheap Hotels in Woodruff
- Luxury Hotels in Woodruff
- Flights to City View
- Flights to Five Forks
- Flights to Golden Grove
- Flights to Greenville - Spartanburg
- Flights to Greenville
- Flights to Simpsonville
- Flights to Welcome
- Flights from Donaldson Center
- Flights from Greenville Downtown
- Flights from Alexander City to Greenville
- Flights from Victoria to Greenville
- Flights from Sans Souci
- Flights from South Bend to Greenville - Spartanburg
- Flights from Greenville - Spartanburg
- Flights from Liverpool to Greenville
- Flights from Dubai to Greenville
- Flights from Warwick to Greenville
- Flights from Anderson (AND) to Greenville (GMU)
- Flights from Mobile (BFM) to Greenville (GMU)
- Flights from Dillon (DLL) to Greenville (GDC)
- Flights from Gulfport (GPT) to Greenville (GDC)
- Flights from Greenwood (GRD) to Greenville (GMU)
- Flights from Indianapolis (IND) to Greenville (GDC)
- Flights from Miami (MIA) to Greenville (GDC)
- Flights from Miami (MIA) to Greenville (GMU)
- Flights from Chicago (ORD) to Greenville (GMU)