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Upstate South Carolina Holiday Rentals

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Holiday Rentals in Upstate South Carolina

Apartment in Greenville Downtown

4.0 star property
9.2 out of 10, Wonderful, (772)
"Excellent stay as always! "
United States
Elena
The price is AU$182
includes taxes & fees
4 Jan - 5 Jan 2026
Mint House Greenville - Downtown

Cottage in Clemson

3.0 star property
10.0 out of 10, Exceptional, (1)
Wooded Cottage - 3 Mi to Clemson University

Aparthotel in Greenville

3.0 star property
9.2 out of 10, Wonderful, (195)
"Great place!"
United States
Daecia
The price is AU$174
includes taxes & fees
8 Dec - 9 Dec
stayAPT Suites Greenville-Haywood Mall

Cabin in Seneca

2.0 star property
9.8 out of 10, Exceptional, (49)
"The place was absolutely magnificent."
United States
David
The price is AU$214
includes taxes & fees
8 Dec - 9 Dec
Postcard Cabins Lake Hartwell, Outdoor Collection by Marriott Bonvoy

Aparthotel in Greenville

4.0 star property
7.6 out of 10, Good, (42)
"Loved the apartment! Very spacious, clean, brand new. Access to bike paths. Seemed like a quirky location but everything is close by car or bike. "
United States
Kathie
Park Place Apartments by Landing

Apartment in Greenville Downtown

2.0 star property
9.4 out of 10, Exceptional, (6)
The price is AU$233
includes taxes & fees
16 Dec - 17 Dec
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Aparthotel in Travelers Rest

4.0 star property
10.0 out of 10, Exceptional, (15)
"great place perfect for more privacy vs. a standard hotel"
United States
John
The price is AU$433
includes taxes & fees
6 Jan - 7 Jan 2026
The Station by Compo Hotels

Apartment in Greenville Downtown

2.0 star property
10.0 out of 10, Exceptional, (7)
The price is AU$220
includes taxes & fees
14 Dec - 15 Dec
Stylish Downtown Greenville Apartment 1 Block Off Main Street

Condo in Greenville Downtown

10.0 out of 10, Exceptional, (173)
"An amazing location and great stay!"
United States
Amanda S.
The price is AU$311
includes taxes & fees
8 Dec - 9 Dec
Riverwalk Falls-lovely one bedroom condo

Cabin in Pickens

3.5 star property
The price is AU$300
includes taxes & fees
8 Dec - 9 Dec
Carolina Camp Cedar

Holiday Home in Seneca

9.8 out of 10, Exceptional, (65)
"Wonderful experience! Great home, location and host."
United States
Christine V.
Deep Water-Keowee Lakefront,Kayaks, Dock, Dog friendly,level water entry, kayaks

Condo in Clemson

10.0 out of 10, Exceptional, (27)
"Great location "
United States
Melanie F.
Adorable & recently renovated condo within walking distance to downtown Clemson.

Cabin in Cleveland

9.8 out of 10, Exceptional, (111)
"Our family of 5 stayed for a visit to The Pretty Place Chapel. House was great, everyone had their own little personal space. Great location to not only The Pretty Place Chapel but many other sights like waterfalls, hiking trails, wonderful restaurants & coffee shops. Would say a 10 out of 10 trip! "
United States
Tiffany B.
The Mountains are calling for You and Yours!

Condo in Greenville Downtown

9.6 out of 10, Exceptional, (105)
"Great location, clean, good communication with the host"
United States
Michael R.
The price is AU$481
includes taxes & fees
8 Dec - 9 Dec
Modern Condo in the Heart of Downtown Greenville

Holiday Home in Greenville

10.0 out of 10, Exceptional, (5)
The price is AU$603
includes taxes & fees
8 Dec - 9 Dec
Upscale Artsy Bungalow-Walk away to Unity Park

Holiday Home in Travelers Rest

10.0 out of 10, Exceptional, (16)
"Great location, clean place, great communication would come back again."
United States
Jeff S.
The price is AU$504
includes taxes & fees
5 Jan - 6 Jan 2026
Spacious 4-bedroom home in charming Travelers Rest with WiFi & Firepit.

Apartment in Greenville

9.2 out of 10, Wonderful, (24)
"Great location and clean condo! We loved the Swamp Rabbit Cafe for breakfast and walking on the swanp rabbit trail, all super close to easily walk to. "
United States
linda S.
The price is AU$295
includes taxes & fees
8 Dec - 9 Dec
2BR 2Bath - Swamp Rabbit Trail Resort

Holiday Home in Clemson

10.0 out of 10, Exceptional, (22)
"Lovely, quiet and spacious yet still walkable to campus."
United States
amy
Great Getaway

Holiday Home in Clemson

10.0 out of 10, Exceptional, (21)
"Check-in was seamless and the house was very cozy."
United States
Amy M.
Walk to Patrick Square for dining and shopping;Spacious house,Perfect for groups

Holiday Home in Seneca

9.8 out of 10, Exceptional, (100)
"Our whole family had a great stay. "
United States
Cameron M.
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Upstate South Carolina Hotel Reviews

Find out more about Upstate South Carolina

Everything you need to know about Upstate South Carolina holiday rentals

Whether you’re excited for the perfect family holiday, a romantic getaway for two, or the ultimate city break, we’ve got the Upstate South Carolina holiday rental for you. At Expedia, you can take your pick from private holiday homes, apartments, cottages, cabins, villas... The list goes on, and on… and on!

There’s just as wide a choice of amenities, too. Maybe you’re dreaming of your own pool, long evenings in a hot tub, or watching the kids laugh through the day at a waterpark. Maybe you just want a quiet retreat in a pet-friendly apartment. Well, we can help you find it. Hunt out the perfect Upstate South Carolina holiday rental for you by simply entering your desired dates. Then check your favourite filters to narrow down your search. 

Upstate South Carolina holiday rentals: An excellent choice for every season

Whenever you want to travel, a warm welcome awaits you in Upstate South Carolina. If you’re looking for a little peace, consider booking during the quieter months, such as  . For more hustle and bustle, you may prefer to visit in . 

Prices vary throughout the year and depend on the property type. Your chosen location and amenities will impact the cost of your trip, too. A Upstate South Carolina holiday rental often works out to be a fantastic, cost-effective option for groups and families visiting for a few nights or longer. And if a hotel room is just too small, get a holiday rental with multiple bedrooms and shared living spaces to kick back in.  The selection of Upstate South Carolina holiday rentals we have selected for you start as low as AU$174 per night. Entering your travel dates in the search wizard might find you even better deals!

How to find incredible deals on Upstate South Carolina rentals

At Expedia, we put the best Upstate South Carolina holiday rentals in one place. All you need to do is take your pick. And as we offer book now, pay later options, as well as free cancellation on some properties, you can plan your trip with total peace of mind. You’ll always find a great deal with Expedia. 

To find some top Upstate South Carolina rental deals, enter your travel dates, and sort your search results by price. You can also filter by budget, so you only see accommodation in your ballpark. Next, add any filters you want—and just like that, you’ve built your dream Upstate South Carolina holiday.

If you’re looking for a little inspiration, browse our latest incredible offers, or use the map to view all accommodation in and around Upstate South Carolina. And to unlock even more fantastic deals, bundle your accommodation, flights, and car rental together to save and book with Expedia in complete confidence.