Midtown Travel Guide
Tourist Guide
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its great live music.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
Enterprise Center
Catch an event at Enterprise Center during your trip to St. Louis. Experience the area's fascinating museums or attend a baseball game.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Small Group Tour With Arch & River Cruise
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St. Louis Premium Driving Tour with Boat Ride & Arch
Gateway Arch National Park Self Guided Audio Walking Tour
Our pick of the best Midtown Hotel Deals
Element St. Louis Midtown
Room was spotless, and the staff were very nice. Valet parking was a plus. Amenities in hotel were great. Rooftop bar was excellent. I can't say enough about the smiles and customer service w each staff we encountered. The best stay I have had in a very long time 5⭐️s
Reviewed on 28 Feb 2026
Residence Inn by Marriott St Louis Downtown
Mean black girl with cheap wig at front desk watch out!! Maintenance men were so sweet and helpful
Reviewed on 24 Feb 2026
Pear Tree Inn St. Louis Near Union Station
Friendly employees and loved the kick back hour plus the free breakfast.
Reviewed on 2 Mar 2026
21C Museum Hotel St Louis
Our room was very dirty. The bath tub had hair leftover from someone shaving and the bathroom floor was disgusting. Most of the furniture had greasy smudges and there appeared to be body fluid on the wall. Also the outlet in the bathroom did not work. We were unable to get ready in the bathroom and ...
Reviewed on 2 Mar 2026
Clayton Plaza Hotel & Extended Stay
Bathroom was ok, like the shower, but the rest of the room was pretty dark and dilapidated. Staff is always exceptional!
Reviewed on 2 Mar 2026
Pear Tree Inn St. Louis Airport
They failed to reserve a suitable room and i had to go elsewhere...at 2 AM!
Reviewed on 2 Mar 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Busch Stadium.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Busch Stadium are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
