Midtown Travel Guide
Tourist Guide
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its acclaimed theatre scene.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's acclaimed theatre scene or attend a baseball game.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's fascinating museums or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
St. Louis Premium Small Group Tour With Arch & River Cruise
St. Louis Ghost Tour: Sinister Sins & Shadows
Our pick of the best Midtown Hotel Deals
Element St. Louis Midtown
Clean room and spacious
Reviewed on 19 Apr 2026
Residence Inn by Marriott St Louis Downtown
Seemed very quite
Reviewed on 19 Apr 2026
Clayton Plaza Hotel & Extended Stay
Front desk is extremely slow.
Reviewed on 18 Apr 2026
Drury Plaza Hotel St. Louis at the Arch
Count on a great breakfast , happy hour drinks and dinner , all included! The staff was incredible, so friendly and willing to help give tips on what to see around the city
Reviewed on 19 Apr 2026
Hollywood Casino & Hotel St. Louis
Accommodating staff, food availability, comfortable.
Reviewed on 19 Apr 2026
Hyatt Regency St. Louis at The Arch
I love this hotel
Reviewed on 19 Apr 2026
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Enterprise Center.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and Enterprise Center.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Enterprise Center are a few top sights nearby.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Zoo and St. Louis Science Center.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
