Midtown Travel Guide
Tourist Guide
Popular places to visit
St. Louis University
Explore the campus of St. Louis University during your stay in St. Louis. Wander around the area's picturesque gardens or experience its fascinating museums.
Scott Joplin House State Historic Site
Learn about the local history of St. Louis when you take a trip to Scott Joplin House State Historic Site. Experience the area's great live music or attend a baseball game.
St. Louis Union Station
You can learn more about the history of St. Louis during your trip to a well-known site such as St. Louis Union Station. Experience the area's great live music or attend a baseball game.
Gateway Arch
Visit the Museum of Westward Expansion, then ascend to the top of the tallest man-made monument in the US for breathtaking views of St. Louis.
St. Louis Zoo
In the middle of St. Louis, meet the exotic and endangered animals that live in meticulously recreated ecosystems from all over the world.
Busch Stadium
Catch an event at Busch Stadium during your trip to St. Louis. Experience the area's great live music or attend a baseball game.
Activities
St. Louis Ghost Tour: Sinister Sins & Shadows
St Louis Ghost Tours: Sinister Sins & Shadows Ghost Tour
Lemp Haunted Neighborhood Walking Tour
St. Louis Premium Driving Tour with Boat Ride & Arch
Best of St. Louis Small Group Tour w/ Arch & River Cruise
Gateway Arch National Park Self Guided Audio Walking Tour
Our pick of the best Midtown Hotel Deals
Element St. Louis Midtown
Clean and modern. Staff is extremely friendly. Great breakfast included. Convenient location.
Reviewed on 10 Nov 2025
Magnolia Hotel St. Louis, a Tribute Portfolio Hotel
Our stay was amazing here, we didn't have breakfast unfortunately but we wished breakfast was complimentary like aome of the other hotels but Overall our stay was great Thank you!
Reviewed on 22 Nov 2025
Hilton St. Louis Airport
The room was clean, the staff was nice, and the hotel had a good atmosphere. The lobby restaurant/bar was busy but not overly crowded. The food was good. The floors with the rooms are quiet.
Reviewed on 15 Nov 2025
Hyatt Regency St. Louis at The Arch
Taylor, at the front desk, was amazing and so helpful. She answered my questions with ease during check-in, and continued to help throughout my stay. Taylor deserves a huge Thank you!
Reviewed on 22 Nov 2025
Drury Plaza Hotel St. Louis at the Arch
Clean. Good breakfast
Reviewed on 26 Nov 2025
Forest Park Hotel by MDR
Great location
Reviewed on 22 Nov 2025
Other neighbourhoods around Midtown
The Gate
While The Gate may not have many sights to explore, venturing just a little farther will lead you to top things to see and do like St. Louis Union Station and Chaifetz Arena.
Downtown West
While visiting Downtown West, you might make a stop by sights like St. Louis Union Station and St. Louis Aquarium at Union Station.
Lafayette Square
The restaurants and shopping are a few reasons travellers visit Lafayette Square. Want to see more of the surrounding area? St. Louis Union Station and Gateway Arch are a few top sights nearby.
Shaw
Shaw might not have many top sights, but Missouri Botanical Gardens and Arboretum and St. Louis Science Center are two attractions nearby that you can check out.
Central West End
If you're looking for things to see and do in Central West End, ample dining options and lush forests are highlights. You might also check out World Chess Hall of Fame while you're visiting, and jump aboard the metro at Central West End Station to get around town.
The Grove
While there might not be top attractions in The Grove, you can explore the larger area and discover places like St. Louis Science Center and Missouri Botanical Gardens and Arboretum.
