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Spa Hotels & Resorts in Southeast Missouri from AU$154
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Our top choices for Southeast Missouri hotels with a spa
1. Hampton Inn Poplar Bluff
Hampton Inn Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,002 reviews)
"Everything was great about the stay!"
Denise
The price is AU$143
includes taxes & fees
8 Nov - 9 Nov
2. Drury Inn & Suites Jackson MO
Drury Inn & Suites Jackson MOJackson
9.6 out of 10, Exceptional, (1,000 reviews)
"Clean room affordable and great breakfast I would definitely go back!"
Lyn
The price is AU$120
includes taxes & fees
8 Nov - 9 Nov
3. Drury Plaza Hotel Cape Girardeau Conference Center
Drury Plaza Hotel Cape Girardeau Conference CenterCape Girardeau
9.6 out of 10, Exceptional, (1,007 reviews)
"Great stay! Hot tub was enjoyable and the staff was super friendly!"
Chris
The price is AU$160
includes taxes & fees
5 Nov - 6 Nov
4. Fairfield Inn & Suites by Marriott Poplar Bluff
Fairfield Inn & Suites by Marriott Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (975 reviews)
"Everything was great- breakfast, cleanliness, price— will stay there again"
ELAINE
The price is AU$156
includes taxes & fees
8 Nov - 9 Nov
5. Hampton Inn By Hilton Dexter
Hampton Inn By Hilton DexterDexter
9.6 out of 10, Exceptional, (81 reviews)
"This place is Brand new and really great!"
Bryan
The price is AU$157
includes taxes & fees
15 Nov - 16 Nov
6. EC Reed's Mercantile and Hotel
EC Reed's Mercantile and HotelMarble Hill
9.4 out of 10, Exceptional, (117 reviews)
"Awesome hotel and staff was first rate, everything was fantastic. If you are in the area, stay at this hotel and eat in!!"
Jan
The price is AU$153
includes taxes & fees
2 Dec - 3 Dec
7. The Riverview
The RiverviewCape Girardeau
9.4 out of 10, Exceptional, (697 reviews)
"Clean, quiet, comfortable room. Very comfortable beds."
Renee
The price is AU$169
includes taxes & fees
2 Nov - 3 Nov
8. La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
La Quinta Inn & Suites by Wyndham Jackson/Cape GirardeauJackson
9.0 out of 10, Wonderful, (890 reviews)
"Breakfast was good."
J
The price is AU$123
includes taxes & fees
8 Nov - 9 Nov
9. Pear Tree Inn Cape Girardeau West
Pear Tree Inn Cape Girardeau WestCape Girardeau
9.2 out of 10, Wonderful, (1,002 reviews)
"The stay was pleasant from start to finish. Extremely nice staff, good breakfast and convenient parking. The location was also great!"
Celeste
The price is AU$116
includes taxes & fees
8 Nov - 9 Nov
10. Fairfield Inn & Suites by Marriott Cape Girardeau
Fairfield Inn & Suites by Marriott Cape GirardeauCape Girardeau
9.4 out of 10, Exceptional, (239 reviews)
"Great hotel…!!"
Carlos
The price is AU$162
includes taxes & fees
5 Nov - 6 Nov
11. Tru By Hilton Cape Girardeau
Tru By Hilton Cape GirardeauCape Girardeau
9.6 out of 10, Exceptional, (198 reviews)
"Had a great stay friendly staff very clean facilities!"
Shannon
The price is AU$145
includes taxes & fees
8 Nov - 9 Nov
12. Drury Inn & Suites Poplar Bluff
Drury Inn & Suites Poplar BluffPoplar Bluff
9.4 out of 10, Exceptional, (1,002 reviews)
"Clean, great food, excellent staff."
Dean
The price is AU$145
includes taxes & fees
8 Nov - 9 Nov
13. Hampton Inn Cape Girardeau I 55 East
Hampton Inn Cape Girardeau I 55 EastCape Girardeau
9.6 out of 10, Exceptional, (856 reviews)
"Everything was lovely. Great room, breakfast, pool, and staff."
Vonnie
The price is AU$157
includes taxes & fees
8 Nov - 9 Nov
14. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHGCape Girardeau
9.4 out of 10, Exceptional, (1,002 reviews)
"Perfect location, beds were awesome & staff were friendly & accommodating!"
Rebecca
The price is AU$154
includes taxes & fees
29 Nov - 30 Nov
15. Courtyard by Marriott Cape Girardeau Downtown
Courtyard by Marriott Cape Girardeau DowntownCape Girardeau
9.6 out of 10, Exceptional, (556 reviews)
"The staff was very friendly and rooms were great!"
Jacqueline
The price is AU$187
includes taxes & fees
15 Nov - 16 Nov
16. Holiday Inn Poplar Bluff by IHG
Holiday Inn Poplar Bluff by IHGPoplar Bluff
8.8 out of 10, Excellent, (799 reviews)
"Always an enjoyable stay"
Nathan
The price is AU$135
includes taxes & fees
8 Nov - 9 Nov
17. TownePlace Suites by Marriott Sikeston
TownePlace Suites by Marriott SikestonSikeston
9.2 out of 10, Wonderful, (29 reviews)
"I liked the lobby, bar and breakfast areas. The full breakfast buffet was awesome. Super nice room with kitchenette. Staff were great."
Mark
The price is AU$176
includes taxes & fees
8 Nov - 9 Nov
18. Shepherd Mountain Inn
Shepherd Mountain InnIronton
9.2 out of 10, Wonderful, (337 reviews)
"Clean room, wifi easy to connect to, parking right in front."
Jonathan
The price is AU$192
includes taxes & fees
2 Nov - 3 Nov
19. Postcard Cabins St Francois, Outdoor Collection by Marriott Bonvoy
Postcard Cabins St Francois, Outdoor Collection by Marriott BonvoyFrench Village
10.0 out of 10, Exceptional, (117 reviews)
"Recomend this location"
Jose
The price is AU$207
includes taxes & fees
30 Nov - 1 Dec
20. Fairfield Inn & Suites by Marriott Sikeston
Fairfield Inn & Suites by Marriott SikestonSikeston
9.4 out of 10, Exceptional, (118 reviews)
"Friendly staff, great breakfast, nice amenities"
Roslyn
The price is AU$163
includes taxes & fees
8 Nov - 9 Nov
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews
Drury Inn & Suites Cape Girardeau
10/10 Excellent
Drury Inn & Suites Jackson MO
10/10 Excellent