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Spa Hotels & Resorts in Southeast Missouri from AU$161

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Check availability on Southeast Missouri Spa Hotels

Tonight
15 Sept - 16 Sept
Tomorrow
16 Sept - 17 Sept
This weekend
18 Sept - 20 Sept
Next weekend
25 Sept - 27 Sept

Our top choices for Southeast Missouri hotels with a spa

A spacious lobby with a fireplace, comfortable seating, a staircase, and a large chandelier.
A hotel room with a bed, desk, chair, TV, and a small kitchenette area.
A living room with a stone fireplace, a television mounted above it, and a large sofa with cushions.
A spacious hotel lobby with a high ceiling, a central seating area with sofas and chairs, a fireplace, and a television mounted on the wall.

1. Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG

Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
Cape Girardeau
  • Luxurious spa sanctuary awaits with full-service treatments and indoor pool in this centrally located hotel.
AU$161
includes taxes & fees
20 Sept - 21 Sept
Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
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Choose what matters most at spa hotels in Southeast Missouri

Pool
Breakfast included
Spa pool
4 stars
5 stars

Top Southeast Missouri Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Great experience- food, cleanliness, friendly staff"
Patti 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

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