Historic Hotels & Resorts in Southeast Missouri from AU$225
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Best Southeast Missouri Historic Hotels

Beautiful Modern Loft In Wine Country!
Beautiful Modern Loft In Wine Country!
10.0 out of 10, Exceptional, (259)
The price is AU$279
includes taxes & fees
11 Aug - 12 Aug

The Weber Farm - Enjoy a beautiful 100 acre farm!
The Weber Farm - Enjoy a beautiful 100 acre farm!
10.0 out of 10, Exceptional, (30)
The price is AU$288
includes taxes & fees
4 Aug - 5 Aug

Doves Nest Guest House<br> Tranquil & Relaxing
Doves Nest Guest House<br> Tranquil & Relaxing
10.0 out of 10, Exceptional, (41)
The price is AU$361
includes taxes & fees
4 Aug - 5 Aug

Serenity South -- Gardens, River-Views, and Refreshing Space
Serenity South -- Gardens, River-Views, and Refreshing Space
10.0 out of 10, Exceptional, (138)
The price is AU$383
includes taxes & fees
4 Aug - 5 Aug

Rest, Relax and Renew. Our log cabin experience awaits your arrival.
Rest, Relax and Renew. Our log cabin experience awaits your arrival.
10.0 out of 10, Exceptional, (389)
The price is AU$311
includes taxes & fees
11 Aug - 12 Aug

Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
Cozy Studio Cottage on "The Hill," walkably close to everything! The Zoo, Park!!
9.8 out of 10, Exceptional, (144)
The price is AU$225
includes taxes & fees
6 Aug - 7 Aug

Charming cottage overlooking Lake Acre
Charming cottage overlooking Lake Acre
10.0 out of 10, Exceptional, (95)
The price is AU$438
includes taxes & fees
4 Aug - 5 Aug

Chic Minimalist Gem w/ Fenced Backyard + W/D
Chic Minimalist Gem w/ Fenced Backyard + W/D
9.6 out of 10, Exceptional, (7)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Top Southeast Missouri Hotel Reviews

Baymont Inn and Suites by Wyndham Farmington, MO
10/10 Excellent
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Hotels near popular Southeast Missouri Attractions
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- Pear Tree Inn Cape Girardeau West
- Candlewood Suites Cape Girardeau by IHG
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Postcard Cabins St. Francois
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55 by IHG
- Drury Inn & Suites Sikeston, MO
- Quality Inn
- Super 8 by Wyndham Farmington
- Tru By Hilton Cape Girardeau
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