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Family Hotels & Resorts in Sikeston from AU$109

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Check availability on Sikeston Family Hotels

Our top choices for Sikeston family-friendly hotels

Property amenity
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

3.0 star property
Sikeston
9.4 out of 10, Exceptional, (1003)
"Clean room, great location and friendly staff"
United States
Mark
The price is AU$156
includes taxes & fees
14 Dec - 15 Dec
Drury Inn & Suites Sikeston, MO
Lobby
Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

3.0 star property
Cape Girardeau
9.6 out of 10, Exceptional, (1001)
"Great place and staff, very accommodating!"
United States
Megan
The price is AU$153
includes taxes & fees
14 Dec - 15 Dec
Drury Plaza Hotel Cape Girardeau Conference Center
Lobby
Pear Tree Inn Cape Girardeau Near the Medical Center

Pear Tree Inn Cape Girardeau Near the Medical Center

2.5 star property
Cape Girardeau
9.0 out of 10, Wonderful, (1005)
"Nice place for a stay at a reasonable price."
United States
Arthur
The price is AU$119
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Cape Girardeau Near the Medical Center
Property amenity
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau

3.0 star property
Jackson
8.8 out of 10, Excellent, (661)
"Great place "
United States
GUY
The price is AU$128
includes taxes & fees
4 Jan - 5 Jan 2026
La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
Lobby
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1002)
"Everything was clean, staff was friendly "
United States
Matthew
The price is AU$130
includes taxes & fees
14 Dec - 15 Dec
Pear Tree Inn Sikeston
Lobby
Fairfield Inn & Suites by Marriott Cape Girardeau

Fairfield Inn & Suites by Marriott Cape Girardeau

2.5 star property
Cape Girardeau
9.4 out of 10, Exceptional, (139)
"Nice hotel, clean and comfortable "
United States
Laura
The price is AU$150
includes taxes & fees
18 Dec - 19 Dec
Fairfield Inn & Suites by Marriott Cape Girardeau
Studio, 1 King Bed
Hampton Inn By Hilton Dexter

Hampton Inn By Hilton Dexter

2.5 star property
Dexter
10.0 out of 10, Exceptional, (1)
"Staff was helpful and professional. The rooms were clean and comfortable "
United States
Michael
The price is AU$165
includes taxes & fees
19 Dec - 20 Dec
Hampton Inn By Hilton Dexter
Property amenity
Candlewood Suites Cape Girardeau by IHG

Candlewood Suites Cape Girardeau by IHG

2.5 star property
Cape Girardeau
8.2 out of 10, Very good, (880)
"Clean room, low noise and very comfortable!"
United States
Richard
The price is AU$127
includes taxes & fees
14 Dec - 15 Dec
Candlewood Suites Cape Girardeau by IHG
Seasonal outdoor pool, open 10:00 AM to 9:00 PM, pool umbrellas
Dexter Inn

Dexter Inn

2.5 star property
Dexter
7.0 out of 10, Good, (332)
"Room was nice and spacious."
United States
Rebecca
The price is AU$110
includes taxes & fees
10 Dec - 11 Dec
Dexter Inn
Desk, laptop workspace, blackout curtains, iron/ironing board
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is AU$109
includes taxes & fees
27 Dec - 28 Dec
Quality Inn Charleston - Sikeston
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Top Sikeston Hotel Reviews

Drury Plaza Hotel Cape Girardeau Conference Center

Drury Plaza Hotel Cape Girardeau Conference Center

10/10 Excellent
"Beds were great. Very clean all around. Very nice breakfast with glutten free bread for my wife. "
Jim 1-night trip
Posted 2 days ago
Drury Plaza Hotel Cape Girardeau Conference Center

Frequently asked questions

What's Sikeston like for family-friendly holidays?
The welcoming destination of Sikeston is a great choice if you've been considering a holiday with the children. The excursions, museums and cafes are just some of the things that make this an attractive spot for a family holiday. Arrange a flight into Cairo, IL (CIR-Cairo Regional), which is located 23.8 mi (38.3 km) from the city centre.
What's the best family accommodation in Sikeston?
Drury Inn & Suites Sikeston, MO is a hotel with an outdoor pool and free parking, and it's a top choice on Expedia for families. Pear Tree Inn Sikeston is another good choice for your stay with the kids.
When's the best time to book a family-friendly holiday in Sikeston?
The hottest months are usually July and August, with an average temperature of 25°C, while the coldest months are January and February, with an average of 5°C. Average annual precipitation for Sikeston is 1536 mm.
What's there to see and do with your family in Sikeston?
While you and the family are holidaying in Sikeston, you may want to explore some of the attractions here such as Front Street Studio & Art Gallery, Central Park and Shawnee National Forest. Make sure that you have lots of time for activities such as Mississippi River and Ohio River Valley.