Santo Tomas Hotels, Mexico City

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Check prices for these dates

Tonight
23 Dec - 24 Dec
Tomorrow
24 Dec - 25 Dec
This weekend
26 Dec - 28 Dec
Next weekend
2 Jan - 4 Jan

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Our top choices for Santo Tomas hotels

Front of property
Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico

Camino Real Aeropuerto Mexico
4.0 star property
Venustiano Carranza, 11.2 km from Santo Tomas
8.8 out of 10, Excellent, (11945)
"Convenient and comfortable hotel right at the airport. Great staff, clean rooms and a great night sleep!"
United States
Charles
The price is AU$269
includes taxes & fees
3 Jan - 4 Jan 2026
Camino Real Aeropuerto Mexico
Breakfast, lunch, dinner served; Mexican cuisine
Hotel Catedral

Hotel Catedral

Hotel Catedral
4.0 star property
Historic Center, 7.2 km from Santo Tomas
9.4 out of 10, Exceptional, (2631)
"Clean room, best pillows Best breakfast I have had in hotels."
United States
Isabel
Hotel Catedral
Restaurant
Verticca Hotel

Verticca Hotel

Verticca Hotel
3.0 star property
29.6 km from Santo Tomas
9.4 out of 10, Exceptional, (251)
"Excelente Hotel"
Mexico
juan Ricardo
Verticca Hotel
Business Suite with living area and street view
We Hotel Aeropuerto

We Hotel Aeropuerto

We Hotel Aeropuerto
3.5 star property
Venustiano Carranza, 10.9 km from Santo Tomas
8.4 out of 10, Very good, (2145)
"easy to check in, facility clean and staff friendly "
Canada
William
The price is AU$171
includes taxes & fees
27 Dec - 28 Dec
We Hotel Aeropuerto
In-room safe, blackout curtains, soundproofing, iron/ironing board
Punta Alameda

Punta Alameda

Punta Alameda
2.0 star property
Downtown Mexico City, 6.9 km from Santo Tomas
9.4 out of 10, Exceptional, (229)
"Clean, nice room"
United States
Maria Teresa Cardoso
The price is AU$122
includes taxes & fees
8 Jan - 9 Jan 2026
Punta Alameda
Breakfast, lunch, dinner served; Mexican cuisine
Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City

Zocalo Central & Rooftop Mexico City
4.0 star property
Historic Center, 7.2 km from Santo Tomas
9.8 out of 10, Exceptional, (2663)
"Great place to stay! "
United States
Guadalupe
The price is AU$332
includes taxes & fees
12 Jan - 13 Jan 2026
Zocalo Central & Rooftop Mexico City
Interior
Courtyard Mexico City Airport

Courtyard Mexico City Airport

Courtyard Mexico City Airport
4.0 star property
Venustiano Carranza, 11.3 km from Santo Tomas
9.4 out of 10, Exceptional, (1816)
"Great staff clean room and so easy to access from airport "
Canada
Jean
The price is AU$271
includes taxes & fees
17 Jan - 18 Jan 2026
Courtyard Mexico City Airport
Indoor pool, open 6 AM to 8 PM, pool loungers
Barceló México Reforma

Barceló México Reforma

Barceló México Reforma
4.5 star property
6.3 km from Santo Tomas
9.4 out of 10, Exceptional, (5105)
"Great hotel!"
United States
Alma
The price is AU$200
includes taxes & fees
11 Jan - 12 Jan 2026
Barceló México Reforma
Exterior
NH Collection Mexico City Airport T2

NH Collection Mexico City Airport T2

NH Collection Mexico City Airport T2
4.0 star property
Venustiano Carranza, 12.7 km from Santo Tomas
8.6 out of 10, Excellent, (3577)
"Excelente hotel"
Mexico
Rosario
The price is AU$302
includes taxes & fees
31 Dec - 1 Jan 2026
NH Collection Mexico City Airport T2
Exterior
Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto

Fiesta Inn Ciudad de Mexico Aeropuerto
3.5 star property
Venustiano Carranza, 10.9 km from Santo Tomas
8.8 out of 10, Excellent, (3219)
"Breakfast was great"
Canada
Silvi
The price is AU$214
includes taxes & fees
2 Jan - 3 Jan 2026
Fiesta Inn Ciudad de Mexico Aeropuerto
Front of property – evening/night
Historico Central Hotel

Historico Central Hotel

Historico Central Hotel
4.0 star property
Historic Center, 7.1 km from Santo Tomas
9.8 out of 10, Exceptional, (2409)
"Very nice staff, clean rooms, very good breakfast options and close to very city amenities."
United States
Maria
The price is AU$289
includes taxes & fees
8 Jan - 9 Jan 2026
Historico Central Hotel
Lobby
Geneve Ciudad de México

Geneve Ciudad de México

Geneve Ciudad de México
4.0 star property
Zona Rosa, 6.9 km from Santo Tomas
9.0 out of 10, Wonderful, (1748)
"Great location, customer service and the hotel was nice and clean "
United States
Victor
The price is AU$169
includes taxes & fees
16 Jan - 17 Jan 2026
Geneve Ciudad de México
Exterior
Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico

Hampton Inn & Suites Mexico City - Centro Historico
3.0 star property
Historic Center, 7.6 km from Santo Tomas
9.0 out of 10, Wonderful, (1093)
"Always a great place to stay while in CDMX "
United States
Juan
The price is AU$130
includes taxes & fees
6 Jan - 7 Jan 2026
Hampton Inn & Suites Mexico City - Centro Historico
Terrace/patio
Hotel Punto MX

Hotel Punto MX

Hotel Punto MX
3.5 star property
Historic Center, 7.4 km from Santo Tomas
9.0 out of 10, Wonderful, (1448)
"I love this hotel...pretty clean, staff courteous, nice location...."
United States
Martha
The price is AU$95
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Punto MX
Presidential Suite, 1 King Bed | Bathroom
Hilton Mexico City Reforma

Hilton Mexico City Reforma

Hilton Mexico City Reforma
4.5 star property
Reforma, 6.5 km from Santo Tomas
9.4 out of 10, Exceptional, (1078)
"Excelent hotel"
United States
Linda
The price is AU$306
includes taxes & fees
3 Jan - 4 Jan 2026
Hilton Mexico City Reforma
Bar (on property)
Camino Real Polanco Mexico

Camino Real Polanco Mexico

Camino Real Polanco Mexico
4.5 star property
6.5 km from Santo Tomas
9.2 out of 10, Wonderful, (3160)
"Great location "
United States
Christina
The price is AU$236
includes taxes & fees
7 Jan - 8 Jan 2026
Camino Real Polanco Mexico
Outdoor pool, open 8:00 AM to 8:00 PM, pool loungers
Hotel Century Reforma

Hotel Century Reforma

Hotel Century Reforma
3.5 star property
Zona Rosa, 7 km from Santo Tomas
8.6 out of 10, Excellent, (1258)
"Great location and accommodations "
United States
Daniel
The price is AU$175
includes taxes & fees
3 Jan - 4 Jan 2026
Hotel Century Reforma
Exterior
Galeria Plaza Reforma

Galeria Plaza Reforma

Galeria Plaza Reforma
4.0 star property
Zona Rosa, 6.8 km from Santo Tomas
9.4 out of 10, Exceptional, (3221)
"Excellent stay "
United States
Arturo
The price is AU$229
includes taxes & fees
6 Jan - 7 Jan 2026
Galeria Plaza Reforma
Front of property
Hotel Juarez

Hotel Juarez

Hotel Juarez
2.5 star property
Historic Center, 7.2 km from Santo Tomas
9.0 out of 10, Wonderful, (1799)
"Excelente hotel"
Mexico
César augusto
The price is AU$52
includes taxes & fees
6 Jan - 7 Jan 2026
Hotel Juarez
Deluxe Suite, 1 King Bed
Econo Express Hotel

Econo Express Hotel

Econo Express Hotel
3.5 star property
Benito Juarez, 12.3 km from Santo Tomas
9.0 out of 10, Wonderful, (1600)
"Great location because the metro is near and the facilities are very quiet and confortable "
United States
Raul Antonio
Econo Express Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Our guide on where to stay in Santo Tomas

Find the best Santo Tomas areas for the activities you enjoy most.

Roma Norte

Known for its fascinating museums and popular shops, there's plenty to explore in Roma Norte. Check out top attractions like MUCA Roma and Centro Cultural El Punto, and jump on the metro at Insurgentes Station or Sevilla Station to see more of the city.

Polanco showing heritage architecture, a church or cathedral and a garden

Polanco

Visit the most diverse section of Mexico City for sophisticated shopping, dining, accommodations and sightseeing.

La Condesa showing café scenes

La Condesa

Enjoy 20th-century history in these two sections of Mexico City, with interesting art and architecture reflecting European influences.

Metropolitan Cathedral showing heritage elements, a church or cathedral and heritage architecture

Historic Center

Consider a visit to Zócalo and take some time to enjoy the interesting museums during your time in Historic Center. If you want to see more of the city, jump on the metro at Allende Station or Bellas Artes Station.

Reforma featuring a city, central business district and night scenes

Reforma

Consider a visit to Paseo de la Reforma and take some time to enjoy the important monuments during your time in Reforma. If you want to see more of the city, jump on the metro at Insurgentes Station or Cuauhtemoc Station.

Top Santo Tomas Hotel Reviews

Galeria Plaza Reforma

Galeria Plaza Reforma

10/10 Excellent
"Excellent stay "
Arturo 3-night trip
Posted 1 day ago
Galeria Plaza Reforma

Frequently asked questions

What is Santo Tomas like?
Travellers will be sure to find plenty to entertain them in Mexico City's Santo Tomas neighbourhood. Consider a visit to Hospital de Jesus Nazareno as part of your Santo Tomas travel plans.
If I need to cancel my hotel reservation in Santo Tomas, will I receive a refund?
Yes! The majority of room reservations are fully refundable if cancelled prior to the hotel's cancellation deadline, which is usually within 24-48 hours of your scheduled arrival. If you have a reservation that's non-refundable, you might be able to cancel it and get a refund within 24 hours of booking. Put your dates in and click on "Search", then use the filter option "fully refundable" to review the top deals on offer in Santo Tomas.
What is there to do around this Mexico City neighbourhood?
Hospital de Jesus Nazareno is an attraction you might want to check out while you're in Santo Tomas. While you're out sightseeing, Mexico City Arena and TecnoParque are a couple of additional sights to visit in Mexico City.