Holiday Homes in Santee

    Plan, book, stay with confidence
    bex rewards loyalty icon
    Be picky
    Search almost a million properties worldwide
    payments icon
    Treat yourself
    Sign in to save 10% or more on thousands of hotels
    Sign in
    today icon
    Change your mind
    Book hotels with free cancellation

Featured Holiday Homes in Santee

SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
On the beach, sun-loungers
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
9.8 out of 10, Exceptional, 211 reviews
"While the fishing was not as good as we hoped it would be, our stay was still awesome. The house has everything we needed and more. Would definitely stay again if we go back to the area and would recommend it to anyone looking for a great place to stay!"
SANITIZED! Lake Marion Lakefront Sandy Beach, Ramp, Sleeps 19, Wi-Fi Cable
Tom Charles Goat Island Fishing Retreat
Property grounds
Tom Charles Goat Island Fishing Retreat
9.8 out of 10, Exceptional, 36 reviews
"I enjoyed my stay here. It is a very nice home. You can walk right out back and fish or just sit by the water. Water view when indoors is nice. Host was very responsive. Please know that you cannot take fish remains to the dump. They have signs, and they told us they do not accept them. When we asked how we should dispose of them, they told us they didn't know, but recommended we dig a hole. So, that was interesting. You only have access to the public dock, which isn't far. Short walk. I was...
Tom Charles Goat Island Fishing Retreat
NEW LISTING! SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Exterior
NEW LISTING! SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
9.8 out of 10, Exceptional, 156 reviews
"This property was great for our needs and I would recommend it to anyone looking for a getaway or event which needs more capacity for guests."
NEW LISTING! SANITIZED Lake Marion Lakefront! Ramp, Sleeps 13, Wi-Fi Cable
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Exterior
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
9.6 out of 10, Exceptional, 14 reviews
"The neighborhood was very quiet. The house was much larger and nicer than the pictures suggest. The fenced backyard was very large, plenty of room to play fetch with our dogs, also enjoyed the front porch. Loved the decor, along with the comfort and coziness of the living room, we were able to do quite a bit of relaxing and enjoy our vacation."
Cozy Cottage Just a Block From a Boat Landing and a Beautiful Pristine Lake
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Property grounds
Golf and Lake fun on Santee! Bring your boat or golf clubs!
9.8 out of 10, Exceptional, 20 reviews
"This is the second time staying here. We Love it. It is so comfortable and welcoming. We had the best time with our family. Thank you again for all the comforts of home!"
Golf and Lake fun on Santee! Bring your boat or golf clubs!
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Microwave, oven, stovetop, dishwasher
Taw Caw Creek Rental - perfect for fishermen - NO PETS
10.0 out of 10, Exceptional, 6 reviews
"Very clean and great communication! Great area!"
Taw Caw Creek Rental - perfect for fishermen - NO PETS
Idyllic Waterfront Escape w/ Private Boat Dock!
Property grounds
Idyllic Waterfront Escape w/ Private Boat Dock!
10.0 out of 10, Exceptional, 21 reviews
"This place is great! We loved being on the lake!"
Idyllic Waterfront Escape w/ Private Boat Dock!
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Aerial view
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, 20 reviews
"Great home, updated and had everything you would need! Super nice decor & inside was very comfortable."
The price is AU$612
per night
19 June - 20 June
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Beautiful Cottage between Lake Moultrie and Lake Marion
Interior
Beautiful Cottage between Lake Moultrie and Lake Marion
9.8 out of 10, Exceptional, 121 reviews
"Great place for fisherman to stay quite neighborhood is very nice people. Has a nice boat dock I have stayed here a lot of times don’t know how many probably 6-8 never any problem."
Beautiful Cottage between Lake Moultrie and Lake Marion
LAKE MARION LAKE FRONT VACATION RENTAL
Terrace/patio
LAKE MARION LAKE FRONT VACATION RENTAL
9.4 out of 10, Exceptional, 72 reviews
"Always a nice, relaxing stay. Quiet neighborhood. Small slue is perfect, especially on a heavy boat traffic weekend."
LAKE MARION LAKE FRONT VACATION RENTAL
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Property grounds
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
9.6 out of 10, Exceptional, 65 reviews
"Property was amazing and perfectly located for what we wanted to do while at lake Marion."
Lake Marion's Big Red House. W/ Dock and Kayaks. Pet Friendly please read policy
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Outdoor dining
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
10.0 out of 10, Exceptional, 122 reviews
"The property was perfect from location& size to the items they have on hand in case you forgot something. Will stay again!!"
Deep water Lake Marion house. 4BR 2.5BA. Fish off dock. Nearby Golf. SUNSETS
Lakefront Retreat on Lake Marion
Property grounds
Lakefront Retreat on Lake Marion
9.6 out of 10, Exceptional, 22 reviews
"Great location on Lake Marion. Dock is set up for fishing and we caught a few big ones. House itself is exactly as described. Maybe not the Ritz, but it's Lake Marion. It's perfect for what it is. Very nice screened in porch looking out over the water. Almost a low country feel to the property and views. About 5 min from I-95 and 10 min from Santee Food Lion. Bedrooms were comfortable and the kitchen was equipped appropriately. Great location for a golf weekend as well - plenty of decent courses...
Lakefront Retreat on Lake Marion
Lake Marion Lakehouse with 180° lake view
Beach
Lake Marion Lakehouse with 180° lake view
10.0 out of 10, Exceptional, 37 reviews
"Our stay was amazing and so relaxing!! Property just as listed, super clean and comfy beds!! Definitely a 5 star stay!!"
Lake Marion Lakehouse with 180° lake view
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Fridge, microwave, oven, stovetop
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
9.4 out of 10, Exceptional, 19 reviews
"Great people"
Beautiful Lake Marion Views!! Pet Friendly! Newly renovated and updated!!
Two Palms Lakehouse in Santee Just minutes from I95
Property grounds
Two Palms Lakehouse in Santee Just minutes from I95
7.6 out of 10, Good, 8 reviews
"Great place for a couple days. We took advantage of the lake. Fishing was great for the grandchildren. I highly recommend this place if you enjoy being by the lake. Thank you."
Two Palms Lakehouse in Santee Just minutes from I95
Archie's Lake Daze Cottage
Property grounds
Archie's Lake Daze Cottage
10.0 out of 10, Exceptional, 58 reviews
"This place was beautiful! Such a peaceful neighborhood, beautiful decor! Tons of kitchen utensils and accessories. Beds were comfortable and rooms were quite adorable! The view is honestly amazing and just breathtaking. Definitely the place to stay if you’re really wanting to unwind and relax 😊"
Archie's Lake Daze Cottage
Dukes Street Retreat 5min from I-95!
Fridge, microwave, oven, stovetop
Dukes Street Retreat 5min from I-95!
7.8 out of 10, Good, 8 reviews
"Everything went well. Host was available when needed."
Dukes Street Retreat 5min from I-95!
Ultimate Hideaway in the pines next to Lake Marion
Fridge, microwave, oven, stovetop
Ultimate Hideaway in the pines next to Lake Marion
10.0 out of 10, Exceptional, 8 reviews
"Lovely property, beautifully decorated and equipped for our party of 5. Very quiet, country location perfect for access to nearby state and national parks."
Ultimate Hideaway in the pines next to Lake Marion
Quaint Orangeburg Townhome Near Hospitals & Campus
Fridge, microwave, stovetop, coffee/tea maker
Quaint Orangeburg Townhome Near Hospitals & Campus
8.0 out of 10, Very good, 2 reviews
"The inside of the property was very clean, there was a snack basket which was awesome. The only issue with the property was the outside lots of trash in and around the building. I would stay there again if we do anymore festivals in Orangeburg. Overall good place just need some outside cosmetic work."
Quaint Orangeburg Townhome Near Hospitals & Campus
Don't see what you're looking for?
See all available properties in Santee
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Other property types in Santee

Executive 2 BR/2 BA Lakefront Corner Suite Condo
Outdoor pool
Executive 2 BR/2 BA Lakefront Corner Suite Condo
9.4 out of 10, Exceptional, 23 reviews
"We really enjoyed our stay. Everything was exactly like the pics. Lake Marion is literally steps outside of the back door. We randomly fished all day and night catching bream, catfish and white perch. Everybody (residents/ vacationers) were all so friendly."
Executive 2 BR/2 BA Lakefront Corner Suite Condo
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Aerial view
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
10.0 out of 10, Exceptional, 20 reviews
"Great home, updated and had everything you would need! Super nice decor & inside was very comfortable."
The price is AU$612
per night
19 June - 20 June
Kindred Spirits Retreat at Lake Marion - Pet Friendly Getaway Minutes from I-95!
Two Palms Lakehouse in Santee Just minutes from I95
Property grounds
Two Palms Lakehouse in Santee Just minutes from I95
7.6 out of 10, Good, 8 reviews
"Great place for a couple days. We took advantage of the lake. Fishing was great for the grandchildren. I highly recommend this place if you enjoy being by the lake. Thank you."
Two Palms Lakehouse in Santee Just minutes from I95
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santee Holiday Homes information

Number of reviews
977
Accommodation
56 Holiday Homes
Lowest Price
AU$612
Highest Price
AU$612

Recent Reviews in Santee
Expedia verified reviews

Tru By Hilton Santee

Tru By Hilton Santee

5/5 Excellent
"The check in was very quick and the staff checking us in was very pleasant "
A verified traveller stayed at Tru By Hilton Santee
Posted 3 days ago
Tru By Hilton Santee