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Alfonsina Hotel Boutique by Inboccaluppo is a favourite with Expedia customers. This hotel offers free breakfast and a restaurant. Reviews from our site also recommend Hampton by Hilton Santa Cruz/Equipetrol, Bolivia and Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel as top options for your trip. See all available top hotels, or vacation rentals in Santa Cruz.

Casa Vida: This highly rated holiday home rental in Santa Cruz is located in a rural location, and has an outdoor pool, a patio and a BBQ to put you at ease in your new surroundings. It has 3 bedrooms, as well as a kitchen with a full-sized fridge, a stovetop and a microwave, so that you can cook with friends or family. Make the most of private gardens in this rental home to help you unwind. Some other homes for rent in Santa Cruz include Mi casa su casa, moderna y chic. and Cozy and independent.
Downtown house JH.. See all vacation rentals in Santa Cruz.

Yes! You'll find that most hotel room reservations are fully refundable if you cancel prior to the accommodation's cancellation deadline, which is often 24 or 48 hours before your arrival date. If you booked a non-refundable reservation, it may still be possible to cancel it and receive a refund within a 24-hour period of your booking. Filter your search by fully refundable to find flexible hotel deals in Santa Cruz.

Based on our traveller reviews, Hostal Killa is a top choice for a less expensive stay. Other choices for your budget-friendly stay include residencial francia - Hostel and Residencial Ikandire II. View all budget hotels in Santa Cruz.

Marriott Santa Cruz de la Sierra Hotel is a hotel with an outdoor pool and a restaurant, and it's a top choice on Expedia for families. Other choices for your child-friendly holiday include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. Also, attractions such as Santa Cruz Zoo and Play Land Amusement Park are fun for children of all ages. Find more child-friendly accommodations in Santa Cruz.

Buganvillas Hotel Suites & Spa is a favourite 4-star hotel for couples, and features in-room massages and rainfall showerheads. See all romantic hotels in Santa Cruz.

Hampton by Hilton Santa Cruz/Equipetrol, Bolivia is a top LGBTQ-friendly hotel that features free breakfast and free Wi-Fi. Swissôtel Santa Cruz De La Sierra and Radisson Hotel Santa Cruz are other good choices for your holiday. See all available hotels listed as LGBTQ-friendly in Santa Cruz.

Hotel LP Equipetrol is a top hotel for people travelling with their pets, and offers a restaurant and concierge services for its human guests. Two other good options for you and your pet's trip include Ibis Santa Cruz DE LA Sierra and Swissôtel Santa Cruz De La Sierra. See more pet-friendly hotel accommodations in Santa Cruz.

Marriott Santa Cruz de la Sierra Hotel is a luxury hotel with a full-service spa and a rooftop terrace, and it's a popular choice for Expedia travellers looking for an elegant place to stay. Camino Real Hotel and Hampton by Hilton Santa Cruz/Equipetrol, Bolivia are other upscale choices for your holiday. Find more luxury hotels in Santa Cruz.

Senses Boutique Hotel is a favourite 3.5-star hotel with our travellers looking for stylish accommodation, and features 52 guestrooms, 3 restaurants and a bar.

Marriott Santa Cruz de la Sierra Hotel is a top hotel with a pool, a full-service spa and free self-parking. A couple of other options that feature an on-site pool include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and TRYP by Wyndham Santa Cruz. View all hotels with pools in Santa Cruz.

Marriott Santa Cruz de la Sierra Hotel is a top luxury spa hotel featuring a pool, a rooftop terrace, a fitness centre and tennis courts. Spend an afternoon at Hotel Spa where you’ll find massage treatments. Other popular spa hotels in Santa Cruz include Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel and Camino Real Hotel. See all spa hotels in Santa Cruz.