Santa Cruz Holidays

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Your Santa Cruz Holiday

You'll find plenty to like about Santa Cruz, from its beaches to its lively atmosphere. When you're ready to spend a bit of time in this interesting city, our Santa Cruz holiday packages will be ideal for you. You'll want to go sightseeing during your trip to Santa Cruz. Make time for big-name attractions such as Plaza 24 de Septiembre, Ventura Mall and Guembe Biocenter. Don't delay visiting this city any longer. The perfect Santa Cruz holiday is a few clicks away with Expedia.

The Annual Holiday Sale

Members save up to 40% on hotels and homes. Plan this year’s big trip and save.

Santa Cruz Holiday

Santa Cruz Essential Information

Language
Spanish
Currency
Bolivian bolivianos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Viru Viru Intl. Airport (VVI)
Max Temp Winter
27ºC
Max Temp Summer
32ºC
Top Sights
Santa Cruz Zoo, San Lorenzo Cathedral and Sacred Art Museum

Our pick of the best Santa Cruz Hotel Deals

Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

3 out of 5
AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
The price is AU$69 per night from 27 Feb to 28 Feb
AU$69
27 Feb - 28 Feb
9.6/10 Exceptional! (90 reviews)
Great value

Reviewed on 21 Feb 2026

Ibis Santa Cruz DE LA Sierra
Camino Real Hotel

Camino Real Hotel

4.5 out of 5
Av. San Martín y 4to. Anillo Santa Cruz
The price is AU$175 per night from 10 Mar to 11 Mar
AU$175
10 Mar - 11 Mar
9/10 Wonderful! (420 reviews)
Spotless, large and comfortable room was well maintained. Friendly and helpful staff. Delicious breakfast buffet. Location is near excellent shopping and dining options.

Reviewed on 5 Feb 2026

Camino Real Hotel
Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

3.5 out of 5
Ave. San Martin, #455 Santa Cruz
The price is AU$184 per night from 29 Mar to 30 Mar
AU$184
29 Mar - 30 Mar
9/10 Wonderful! (362 reviews)
Lovely staff. Great buffets.

Reviewed on 23 Feb 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Discover the most popular places to visit in Santa Cruz

What to do in Santa Cruz

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.