Santa Cruz Holidays

Book a Hotel + Flight or Car together to unlock savings

  • Plan, book, travel with confidence

  • Better together

    Save up to AU$2,500 when you book a flight and hotel together*
  • Find the right fit

    With over 300,000 hotels worldwide, it's easy to create a perfect package
  • Rest easy

    Plan, book, and manage your trip all in one place

Your Santa Cruz Holiday

You'll find plenty to like about Santa Cruz, from its beaches to its lively atmosphere. When you're ready to spend a bit of time in this interesting city, our Santa Cruz holiday packages will be ideal for you. You'll want to go sightseeing during your trip to Santa Cruz. Make time for big-name attractions such as Plaza 24 de Septiembre, Ventura Mall and Guembe Biocenter. Don't delay visiting this city any longer. The perfect Santa Cruz holiday is a few clicks away with Expedia.

Santa Cruz Holiday

Santa Cruz Essential Information

Language
Spanish
Currency
Bolivian bolivianos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Viru Viru Intl. Airport (VVI)
Max Temp Winter
27ºC
Max Temp Summer
32ºC
Top Sights
Santa Cruz Zoo, San Lorenzo Cathedral and Sacred Art Museum

Our pick of the best Santa Cruz Hotel Deals

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel

Ave. San Martin, #455 Santa Cruz
AU$189
30 Aug - 31 Aug
9/10 Wonderful! (401 reviews)
"Great breakfast and beautiful property. Would come here again. Felt safe and comfortable."

Reviewed on 16 Aug 2026

Los Tajibos, Santa Cruz de la Sierra, a Tribute Portfolio Hotel
Ibis Santa Cruz DE LA Sierra

Ibis Santa Cruz DE LA Sierra

AVENIDA CRISTOBAL DE MENDOZA Santa Cruz
AU$50
10 Sept - 11 Sept
9.4/10 Exceptional! (134 reviews)
"Buen hotel Limpio y comodo"

Reviewed on 21 Aug 2026

Ibis Santa Cruz DE LA Sierra
Marriott Santa Cruz de la Sierra Hotel

Marriott Santa Cruz de la Sierra Hotel

4to Anillo Entre Radial 23 Santa Cruz Santa Cruz
AU$148
4 Sept - 5 Sept
9/10 Wonderful! (246 reviews)
"Staff was super as well as how clean the room was."

Reviewed on 23 Aug 2026

Marriott Santa Cruz de la Sierra Hotel
See all 310 properties in Santa Cruz
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Stay near popular Santa Cruz attractions

A historic building with arched windows and a clock. People are sitting and standing on the steps in front of the building.

Plaza 24 de Septiembre

8.8/10 (164 reviews)
Plaza 24 de Septiembre buzzes with local culture beneath swaying palms and colonial architecture. Climb the Cathedral's bell tower for spectacular city views while sampling authentic Bolivian coffee from vendors.
See properties
An interior of a church with high arched ceilings, wooden pews, and a central altar.

San Lorenzo Cathedral

9.0/10 (84 reviews)
This grand neoclassical cathedral dominates Santa Cruz's skyline with its towering spires and ornate façade. Climb the bell tower at sunset for breathtaking panoramic views of the city.
See properties

Ventura Mall

9.0/10 (183 reviews)
Ventura Mall, Santa Cruz's premier shopping destination, features international brands and local boutiques. Enjoy the cinema complex, food court, and entertainment options in this contemporary Bolivian retail hub.
See properties

Guembe Biocenter

8.8/10 (60 reviews)
This vibrant ecological sanctuary showcases hundreds of butterfly species in a lush, tropical environment. Explore walking trails, enjoy boat rides, and learn about biodiversity in this serene natural retreat.
See properties

Santa Cruz Zoo

8.4/10 (53 reviews)
The Santa Cruz Municipal Zoo showcases Bolivia's native wildlife in naturalistic habitats, featuring jaguars, tapirs, and free-ranging sloths. Morning visits offer the best chance to see active animals.
See properties

Cine Center

8.0/10 (53 reviews)
This premier entertainment complex offers state-of-the-art cinema experiences with immersive 4D E-Motion formats. Enjoy the latest films, then explore the shopping centre and diverse dining options in the food court.
See properties

Ramon Tahuichi Aguilera Stadium

8.4/10 (18 reviews)
This multi-purpose stadium hosts Bolivia's most passionate football rivalries and tournaments. Experience the electric atmosphere of a local derby while enjoying modernised facilities and vibrant Santa Cruz culture.
See properties

Las Brisas Shopping Center

8.4/10 (40 reviews)
This modern complex offers 80+ stores, a nine-screen cinema, and a unique outdoor restaurant promenade. Explore the gastronomic boulevard for dining experiences beyond the standard food court options.
See properties

What to do in Santa Cruz

Private Tour of Santa Cruz: We'll visit the center, Porongo, markets, and the river

Santa Cruz and Porongo: History, Markets, River, and Culture

AU$93
per adult
Santa Cruz and Porongo: History, Markets, River, and Culture
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

Santa Cruz: Wildlife Sanctuary and Preservation Park Tour

AU$122
per adult
Santa Cruz: Wildlife Sanctuary and Preservation Park Tour
Fuerte de Samaipata, Bolivia

Samaipata Fort Tour: Ancient Ruins in 1 Full Day

AU$451
per adult
Samaipata Fort Tour: Ancient Ruins in 1 Full Day
See all activities in Santa Cruz

Frequently asked questions

How much does a Santa Cruz holiday package cost?
You'll find cheap prices on Expedia for your Santa Cruz break. However, a range of factors like the hotel choice, length of stay and season will determine how much your holiday to Santa Cruz costs.
What are the cheapest months to go to Santa Cruz?
February, April and May are the best times to look for cheap Santa Cruz holiday packages. Opting to travel in quieter months means you can typically find lower prices on hotels and flights.
How many days is enough for Santa Cruz?
Typically, a handful of days is enough to tick off the main sights during your Santa Cruz holiday. However, if you prefer to have some time to kick back or take day tours, think about extending your itinerary.
Is it worth booking a holiday package to Santa Cruz?
Santa Cruz is a good holiday destination with attractions like Ventura Mall among the many things to keep you busy. Whether you're travelling with the family or getting away with friends, a Santa Cruz holiday promises a good time for everyone.
How to find the best Santa Cruz package deals?
Use Expedia's filters to help you find some tempting Santa Cruz package deals. When you start your search, simply set your maximum budget and then sort the results by "Price: low to high." If you're looking to save, plan your break for midweek, or look for Santa Cruz package deals in the off-peak season. Play around with your travel dates and you may land even better discounts. As a rule of thumb, it's usually best to lock in your holiday package as early as possible.
Is it cheaper to book a Santa Cruz holiday as a package?
You can enjoy significant savings on your Santa Cruz escape by booking a personalised holiday package. Click on the "Package" heading, then enter your travel dates and destination to browse some great hotel prices and airfares. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a rental car and you may score a better deal.
When to book a holiday package to Santa Cruz?
If you're considering an impromptu Santa Cruz adventure, browse our last-minute deals that can be booked up to a week before you take off. Don't want to leave things to the last minute? You can find sensational deals on your flights and hotels by booking well in advance.
How to plan a trip to Santa Cruz?
  1. Choose your dates: What you want to do in Santa Cruz and your favourite season will help you decide when to get away.
  2. Work out your budget: Make sure you have enough money to pay for everything from transportation and dining out to experiences and flights. Your hotel will probably be the biggest expense during your trip to Santa Cruz.
  3. Work out your trip length: Consider how much time you want to spend discovering Santa Cruz. Plan your days so you can get to all the experiences and attractions you're interested in without rushing.
  4. Combine your hotel and flights: Epic destination, check. Length of stay, check. All that's left is to choose a Santa Cruz holiday package that brings all your bookings together.

Explore a world of travel with Expedia

* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.