Name: Megapolis Hotel Panamá
Price range: AU$300
Rating: 8.4

Stay near popular Santa Ana attractions

El Machetazo Santa Ana

You can browse for the perfect souvenirs at El Machetazo Santa Ana during your visit to Panama City. Amble around the area's parks or visit its shops.

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Activities

Panama City Visit an Indian town Embera and waterfall with lunch

AU$60

per adult

96% of travellers recommend

Half day of Panama city and canal tour: shared and private

AU$95

per adult

98% of travellers recommend

Panama City: Poin Glass Observation Deck Ticket with VR Tour

AU$46

per adult

100% of travellers recommend

Panama City: Poin Full Package Experience

AU$222

per adult

98% of travellers recommend

San Blas Island-Hopping : Full-Day Adventure from Panama City

AU$193

per adult

Panama City: Legends and Hidden Gems of Casco Viejo Tour

AU$56

per adult

See all activities in Panama City

Our pick of the best Santa Ana Hotel Deals

Casco View Apartments

C. 16 Oeste Panama City Provincia de Panamá

AU$144

31 Aug - 1 Sept

includes taxes & fees

Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...

Hotel Riu Plaza Panama

Calle 50, Urb. Marbella Panama City Panama

AU$203

28 Sept - 29 Sept

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...

9/10 Wonderful! (5,865 reviews)

"The breakfast was excellent and the staff was great. All in all, the hotel is an A+"

Reviewed on 29 Aug 2026

Crowne Plaza Panama Airport by IHG

Ave. Domingo Diaz Tocumen Panama

AU$197

26 Sept - 27 Sept

includes taxes & fees

Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...

8.6/10 Excellent! (2,685 reviews)

"Staff was friendly."

Reviewed on 29 Aug 2026

Central Hotel Panama Casco Viejo

Plaza de la Independencia Casco Viejo Panama City Panama

AU$280

27 Sept - 28 Sept

includes taxes & fees

Stay at this spa hotel in Panama City. Enjoy free Wi-Fi, a full-service spa and 3 restaurants. Our guests praise the helpful staff and the clean rooms in their ...

9.2/10 Wonderful! (1,007 reviews)

"Don’t expect to sleep Upon checkin I was out in my “Jr Suite”. It was just a room. But worse, I tried to soon and heard a rhythmic banging that was impossible to sleep through. It was so bad that I decided to see what it was. My room was DIRECTLY UNDER the gym, in a centuries old building?! If anyone ..."

Reviewed on 29 Aug 2026

Dreams Playa Bonita Panama - All Inclusive

KM 7, Road to Veracruz Veracruz Panama

AU$378

30 Aug - 31 Aug

includes taxes & fees

Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...

7.8/10 Good! (1,066 reviews)

"A Beautiful and Memorable Stay My wife and I had the pleasure of spending an entire week at this beautiful hotel, and our experience was truly memorable from beginning to end. What stood out to us most was the exceptional customer service. Every member of staff we encountered was incredibly polite, ..."

Reviewed on 29 Aug 2026

Megapolis Hotel Panamá

Avenida Balboa Panama City

AU$300

3 Sept - 4 Sept

includes taxes & fees

Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...

8.4/10 Very good! (1,685 reviews)

"El agua caliente no funcionaba me cambiaron de habitación y no funcionaba el control del TV y no hubo quien lo arreglara"

Reviewed on 28 Aug 2026

See all 1,802 properties in Santa Ana

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

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Our guide on where to stay in Santa Ana

Find the best Santa Ana areas for the activities you enjoy most.

A coastal cityscape with buildings, a hill with a church, and a clear blue sky.

Casco Viejo

Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.

A spiraling skyscraper against a clear blue sky.

Bella Vista

Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.

A city skyline with modern high-rise buildings and a river in the foreground.

El Cangrejo

The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.