Top Hotels Near El Machetazo Santa Ana in Panama City from AU$213

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Check prices for these dates

Tonight
15 Nov - 16 Nov
Tomorrow
16 Nov - 17 Nov
Next weekend
20 Nov - 22 Nov
In two weeks
27 Nov - 29 Nov

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Our top choices for El Machetazo Santa Ana hotels

A multi-story building with ornate balconies, large windows, and decorative moldings.

1. Hotel Plaza Herrera

Hotel Plaza Herrera
4.0 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (54 reviews)
"A small old world style hotel. Beautifully restored (the woodwork is beautiful too ) The staff is lovely and extremely helpful. Immaculate. Breakfast downstairs was delicious. Very low key, relaxed place and very conveniently located."
United States
Sharon
The price is AU$394
includes taxes & fees
23 Nov - 24 Nov
Hotel Plaza Herrera
A restaurant with multiple dining tables, chairs, and a central water feature.

2. Hotel La Compañía Casco Antiguo

Hotel La Compañía Casco Antiguo
5.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (380 reviews)
"Location was perfect"
United States
Graham
The price is AU$532
includes taxes & fees
1 Dec - 2 Dec
Hotel La Compañía Casco Antiguo
A balcony with a table, chairs, and a view of a city skyline across a body of water.

3. Sofitel Legend Casco Viejo, Panama City

Sofitel Legend Casco Viejo, Panama City
5.0 star property
San Felipe, 0.8 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (774 reviews)
"Amazing service and beautiful hotel"
United States
Jose
The price is AU$614
includes taxes & fees
17 Nov - 18 Nov
Sofitel Legend Casco Viejo, Panama City
A modern living room with a sectional sofa, a small ottoman, a flat-screen TV, and abstract art on the walls.

4. Casa Bianca

Casa Bianca
2.0 star property
Bella Vista, 2.6 km from El Machetazo Santa Ana
9.8 out of 10, Exceptional, (8 reviews)
"Good place , nice, clean, "
United States
Jose A
The price is AU$239
includes taxes & fees
16 Dec - 17 Dec
Casa Bianca
A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.

5. La Concordia Boutique Hotel

La Concordia Boutique Hotel
4.0 star property
San Felipe, 0.2 km from El Machetazo Santa Ana
9.6 out of 10, Exceptional, (244 reviews)
"Such a beautiful and highly curated and very helpful staff."
United States
Jadah
The price is AU$365
includes taxes & fees
30 Nov - 1 Dec
La Concordia Boutique Hotel
A restaurant interior with checkered flooring, wooden tables, wicker chairs, and hanging wicker lamps.

6. Amarla Boutique Hotel Casco Viejo Adults Only

Amarla Boutique Hotel Casco Viejo Adults Only
3.0 star property
San Felipe, 0.6 km from El Machetazo Santa Ana
9.6 out of 10, Exceptional, (152 reviews)
"It was a great place to stay, right in the center of old Panama City. Even though it is small it is very quaint and efficiently run. It is also convenient that they have a restaurant in-house. Just making stuff convenient"
United States
Glenn
The price is AU$338
includes taxes & fees
22 Nov - 23 Nov
Amarla Boutique Hotel Casco Viejo Adults Only
A spacious indoor area with high ceilings, large windows, and multiple dining tables.

7. American Trade Hotel

American Trade Hotel
4.5 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (828 reviews)
"Beautiful property in great location. Excellent facilities"
United States
Lesley
The price is AU$364
includes taxes & fees
22 Nov - 23 Nov
American Trade Hotel
A spacious outdoor patio with wicker furniture, potted plants, and umbrellas providing shade.

8. Hotel San Felipe

Hotel San Felipe
4.0 star property
San Felipe, 0.4 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (479 reviews)
"Loved our stay! Central, clean, wonderful staff"
United States
RoseMarie
The price is AU$255
includes taxes & fees
16 Nov - 17 Nov
Hotel San Felipe
A multi-story building with balconies, large windows, and a clear blue sky.

9. Las Clementinas

Las Clementinas
3.5 star property
San Felipe, 0.2 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (208 reviews)
"Beautiful property and great restaurant! Also awesome customer service"
United States
Denise
The price is AU$235
includes taxes & fees
14 Dec - 15 Dec
Las Clementinas
A spacious living area with a modern sofa, a wooden coffee table, and a staircase leading to an upper level.

10. Casa Lefevre By Wynwood House

Casa Lefevre By Wynwood House
3.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.6 out of 10, Exceptional, (16 reviews)
"Staff was courteous, and the room was very beautiful. Would stay here again!"
United States
Selam
The price is AU$213
includes taxes & fees
16 Nov - 17 Nov
Casa Lefevre By Wynwood House
A multi-story building with balconies, arched windows, and decorative railings.

11. Central Hotel Panama Casco Viejo

Central Hotel Panama Casco Viejo
4.0 star property
San Felipe, 0.5 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,010 reviews)
"Great location."
United States
Brian
The price is AU$267
includes taxes & fees
29 Nov - 30 Nov
Central Hotel Panama Casco Viejo
A rooftop pool area with lounge chairs and a bar, overlooking a city skyline at sunset.

12. Marriott Panama Hotel

Marriott Panama Hotel
4.0 star property
2.4 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,000 reviews)
"Excellent location"
United States
Guadalupe
The price is AU$289
includes taxes & fees
4 Dec - 5 Dec
Marriott Panama Hotel
A hotel room with a bed, a desk with a computer, a chair, a mirror, and a staircase.

13. Hotel Bardot Boutique

Hotel Bardot Boutique
3.0 star property
San Felipe, 0.8 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (69 reviews)
"Excellent location to walk around, visit local attractions and restaurants in the old city."
United States
Luz
The price is AU$138
includes taxes & fees
16 Nov - 17 Nov
Hotel Bardot Boutique
A modern living room with a sofa, round black ottomans, and a vase of flowers. A cityscape is visible through the window.

14. Bristol Panama, a Registry Collection Hotel

Bristol Panama, a Registry Collection Hotel
5.0 star property
Bella Vista, 3.2 km from El Machetazo Santa Ana
9.2 out of 10, Wonderful, (1,001 reviews)
"Great Hotel!.... Great location!"
United States
Aldo
The price is AU$430
includes taxes & fees
27 Nov - 28 Nov
Bristol Panama, a Registry Collection Hotel
A modern hotel pool area with lounge chairs and a clear view of the ocean.

15. Hilton Panama

Hilton Panama
5.0 star property
Bella Vista, 3 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Everything was great"
United States
ARIELA
The price is AU$378
includes taxes & fees
13 Dec - 14 Dec
Hilton Panama
A rooftop pool area with lounge chairs and tables, surrounded by a city skyline at dusk.

16. Yoo Apartamento

Yoo Apartamento
3.0 star property
Bella Vista, 2.9 km from El Machetazo Santa Ana
9.4 out of 10, Exceptional, (28 reviews)
"Everything was great!! Would definitely book again on my next trip to Panamá"
United States
Sheena
The price is AU$260
includes taxes & fees
16 Nov - 17 Nov
Yoo Apartamento
A modern restaurant with large windows offering a city view, warm lighting, and contemporary furniture.

17. W Panama

W Panama
5.0 star property
Campo Alegre, 3.2 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"Clean room, friendly staff!"
United States
Lashann
The price is AU$431
includes taxes & fees
28 Nov - 29 Nov
W Panama
A modern indoor pool area with clear blue water, lounge chairs, and a wall of plants.

18. Casco View Life Residences

Casco View Life Residences
4.0 star property
Santa Ana, 0.2 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (114 reviews)
"Amazing location and comfort"
United States
Ruben
The price is AU$177
includes taxes & fees
17 Nov - 18 Nov
Casco View Life Residences
A person seated at a bar with a drink, in a room with a teal accent wall and hanging lights.

19. Waldorf Astoria Panama

Waldorf Astoria Panama
5.0 star property
Bella Vista, 2.9 km from El Machetazo Santa Ana
9.0 out of 10, Wonderful, (1,000 reviews)
"The room was very nice, the bar staff and front desk staff were very helpful."
United States
Oscar
The price is AU$447
includes taxes & fees
14 Dec - 15 Dec
Waldorf Astoria Panama
A resort with a pool area, lounge chairs, and a view of a bridge at night.

20. Radisson Hotel Panama Canal

Radisson Hotel Panama Canal
4.5 star property
Amador, 2.4 km from El Machetazo Santa Ana
8.6 out of 10, Excellent, (1,002 reviews)
"The best beds of Panama and an extensive breakfast to start the day with"
United States
Hanspeter
The price is AU$127
includes taxes & fees
29 Nov - 30 Nov
Radisson Hotel Panama Canal
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
View all properties

Compare popular hotels close to El Machetazo Santa Ana

Property
Property class
Guest rating
Breakfast included
Pool
Spa
Pet-friendly
WiFi included
A multi-story building with ornate balconies, large windows, and decorative moldings.
Hotel Plaza Herrera
4.0 star property
9.8
Exceptional
54 reviews
View
A restaurant with multiple dining tables, chairs, and a central water feature.
Hotel La Compañía Casco Antiguo
5.0 star property
9.8
Exceptional
380 reviews
View
A balcony with a table, chairs, and a view of a city skyline across a body of water.
Sofitel Legend Casco Viejo, Panama City
5.0 star property
9.8
Exceptional
774 reviews
View
A modern living room with a sectional sofa, a small ottoman, a flat-screen TV, and abstract art on the walls.
Casa Bianca
2.0 star property
9.8
Exceptional
8 reviews
View
A grand, illuminated building with a symmetrical facade, multiple balconies, and a prominent entrance.
La Concordia Boutique Hotel
4.0 star property
9.6
Exceptional
244 reviews
View

Hotels recommended for families near El Machetazo Santa Ana

A wooden door with a number plate, a black and white striped bag, and a lantern on the ground.

Hotel Casa Panamá

Hotel Casa Panamá
4.0 star property
Casco Viejo
7.6 out of 10, Good, (778)
The price is AU$107
includes taxes & fees
30 Nov - 1 Dec
Hotel Casa Panamá

Other attractions near El Machetazo Santa Ana

Amador Theater

Get tickets for a show at Amador Theater, a popular theatre in Panama City. Visit the shops and top-notch restaurants in this vibrant area.
See properties

Top El Machetazo Santa Ana Hotel Reviews

A multi-story building with ornate balconies, large windows, and decorative moldings.
Hotel Plaza Herrera

Hotel Plaza Herrera

Hotel Plaza Herrera
Casco Viejo

10/10 Excellent

We had a lovely stay. Rooms are beautiful and very large. Staff are very friendly and helpful. No kettle in the rooms. No elevators which we loved but may not suit everyone.
Australia
Natalie
Reviewed March 12, 2026
Hotel Plaza Herrera

Frequently Asked Questions

What's the area like around El Machetazo Santa Ana?

El Machetazo Santa Ana is located in Panama City. If you're looking for a convenient place to stay, take a look at the 518 hotels and other accommodation options you'll find within a mile.

Where is the best place to stay close to El Machetazo Santa Ana?

Adjacent to El Machetazo Santa Ana, Hotel Casa Panamá is one of the top choices for your stay based on our traveller data, and this hotel offers 2 restaurants and a nightclub. Other good choices close by include Central Hotel Panama Casco Viejo and Hotel Faranda Express Soloy and Casino, a member of Radisson Individuals.

How many hotels will I find close to El Machetazo Santa Ana?

Expedia has 518 hotels and other accommodation options within a mile from El Machetazo Santa Ana.

If I need to cancel the hotel reservation for my stay near El Machetazo Santa Ana, will I receive a refund?

Yes! Most hotel bookings are fully refundable as long as you cancel before the hotel’s cancellation deadline, which often is within 24-48 hours of your scheduled arrival. If your reservation is non-refundable, you might be able to cancel it and get a refund within a 24-hour period of your booking. Add dates, click "Search", then filter by "fully refundable" to review the top deals on offer near El Machetazo Santa Ana.

What can I see and do near El Machetazo Santa Ana?

You'll want to browse the collections at Interoceanic Canal Museum, Biomuseo and Mola Museum. Explore landmarks like Iglesia del Carmen, Panama Canal Railway and Iglesia de la Merced. You can check out the local talent at National Theater, Amador Theater and Anita Villalaz Theater.