Santa Ana Travel Guide
Tourist Guide
Visit Santa Ana
Stay near popular Santa Ana attractions
Activities
From Panama City: San Blas Island Hopping Day Tour
AU$204
per adult
98% of travellers recommend
Panama City: All-Inclusive Catamaran Cruise to Taboga Island
AU$139
per adult
94% of travellers recommend
Half day of Panama city and canal tour: shared and private
AU$94
per adult
96% of travellers recommend
Panama: Monkey and Sloth Jungle Habitat Panama Tour
AU$84
per adult
100% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
AU$45
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
AU$58
per adult
96% of travellers recommend
Our pick of the best Santa Ana Hotel Deals
Hotel Caracas - Casco Viejo
Plaza De Santa Ana Panama City Provincia di Panama
The price is AU$54 per night from 11 Nov to 12 Nov
AU$54
11 Nov - 12 Nov
includes taxes & fees
Stay at this hotel in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall and Cinta Costera ...
8/10 Very good! (20 reviews)
"Good location but basic otherwise. Staff not overly helpful on the whole."
Reviewed on 27 Sept 2026
Casco View Life Residences
C. 16 Oeste Panama City Provincia de Panamá
The price is AU$160 per night from 15 Oct to 16 Oct
AU$160
15 Oct - 16 Oct
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is AU$208 per night from 26 Oct to 27 Oct
AU$208
26 Oct - 27 Oct
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (6,082 reviews)
"Breakfast buffet was generally good but there were not enough selections of cooked meats. Bacon was only offered twice during my visit and the other days the meat was like a hard hot dog."
Reviewed on 13 Oct 2026
Hotel El Panama by Faranda Grand, a member of Radisson Individuals
Via Espana 111 Panama City Panama
The price is AU$194 per night from 12 Nov to 13 Nov
AU$194
12 Nov - 13 Nov
includes taxes & fees
Stay at this spa hotel in Panama City. Enjoy free breakfast, free parking and a full-service spa. Our guests praise the helpful staff in their reviews. Popular ...
7.8/10 Good! (1,004 reviews)
"Great"
Reviewed on 12 Oct 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is AU$225 per night from 9 Nov to 10 Nov
AU$225
9 Nov - 10 Nov
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,762 reviews)
"The staff were friendly and very professional. Well versed in English to accommodate our lack of Spanish. Very beautiful hotel."
Reviewed on 13 Oct 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is AU$253 per night from 31 Oct to 1 Nov
AU$253
31 Oct - 1 Nov
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Santa Ana
Find the best Santa Ana areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by Fabiola Tile
Open Photo by Fabiola Tile
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina Station. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
San Felipe
While visiting San Felipe, you might make a stop by sights like Independence Square and Interoceanic Canal Museum.
