Santa Ana Travel Guide
Tourist Guide
Visit Santa Ana
Stay near popular Santa Ana attractions
Activities
Half day of Panama city and canal tour: shared and private
AU$97
per adult
98% of travellers recommend
Panama City: POIN Swing Experience
AU$47
per adult
100% of travellers recommend
Panama City Visit an Indian town Embera and waterfall with lunch
AU$71
per adult
96% of travellers recommend
Boat tour in the Panama Canal to Monkeys and sloths islands
AU$107
per adult
98% of travellers recommend
Panama City: Poin Glass Observation Deck Ticket with VR Tour
AU$47
per adult
100% of travellers recommend
Our pick of the best Santa Ana Hotel Deals
Casco View Apartments
C. 16 Oeste Panama City Provincia de Panamá
The price is AU$180 per night from 21 July to 22 July
AU$180
21 July - 22 July
includes taxes & fees
Stay at this business-friendly condo in Panama City. Enjoy free Wi-Fi, breakfast (surcharge) and a 24-hour front desk. Popular attractions Albrook Shopping Mall ...
9/10 Wonderful! (100 reviews)
"Great layout with modern convenience for my family, sofa bed was generous and comfortable. Thoughtful kitchen tools made our stay easy."
Reviewed on 20 June 2026
Hotel Riu Plaza Panama
Calle 50, Urb. Marbella Panama City Panama
The price is AU$232 per night from 28 July to 29 July
AU$232
28 July - 29 July
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and 3 restaurants. Our guests praise the breakfast and the pool in their reviews. ...
9/10 Wonderful! (5,738 reviews)
"My 23rd Floor had water damage and smelled like mildew."
Reviewed on 15 July 2026
Crowne Plaza Panama Airport by IHG
Ave. Domingo Diaz Tocumen Panama
The price is AU$174 per night from 11 Aug to 12 Aug
AU$174
11 Aug - 12 Aug
includes taxes & fees
Stay at this family-friendly hotel in Tocumen. Enjoy free Wi-Fi, breakfast (surcharge) and a free airport shuttle. Our guests praise the breakfast and the pool ...
8.6/10 Excellent! (2,632 reviews)
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Reviewed on 14 July 2026
Megapolis Hotel Panamá
Avenida Balboa Panama City
The price is AU$234 per night from 3 Aug to 4 Aug
AU$234
3 Aug - 4 Aug
includes taxes & fees
Stay at this luxury hotel in Panama City. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the breakfast and the helpful staff in their reviews. ...
8.4/10 Very good! (1,598 reviews)
"Rooms were immaculate, breakfast was great every morning. Cleaning was strange. I place my bag in the closet and the maid cleaned that out. I put in the closet to be safe, it WAS NOT."
Reviewed on 14 July 2026
Dreams Playa Bonita Panama - All Inclusive
KM 7, Road to Veracruz Veracruz Panama
The price is AU$458 per night from 22 July to 23 July
AU$458
22 July - 23 July
includes taxes & fees
Stay at this beach resort in Veracruz. Enjoy free breakfast, free Wi-Fi and free parking. Our guests praise the pool and the helpful staff in their reviews. ...
7.6/10 Good! (1,021 reviews)
"The hotel is beautiful; the views and its location make you feel like you are on a secluded island. The staff w outstanding, and the room was cleaned every day and smelled really good. Our beachfront view was a plus. Room service was great as well. We loved Geraldine from the kids club! She was amazing ..."
Reviewed on 14 July 2026
Principe Hotel and Suites
Via Argentina Panama City Panama
The price is AU$89 per night from 12 Aug to 13 Aug
AU$89
12 Aug - 13 Aug
includes taxes & fees
Stay at this business-friendly hotel in Panama City. Enjoy free Wi-Fi, free parking and room service. Our guests praise the helpful staff and the clean rooms ...
9/10 Wonderful! (1,960 reviews)
"Our stay at the Principe hotel was a great 5 night stay,the room was clean, spacious,relaxing and the AC was cooling great. The hotel is in a great location, everything in walking distance (restaurants,bars, convenient stores to buy snacks). We will definitely booked a room at the Principe hotel ..."
Reviewed on 15 July 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Our guide on where to stay in Santa Ana
Find the best Santa Ana areas for the activities you enjoy most.
Casco Viejo
Unique features of Casco Viejo include the historical sites and bars. Make a stop by Independence Square or Interoceanic Canal Museum while you're exploring the area.
Photo by My World
Open Photo by My World
Bella Vista
Travellers love Bella Vista for its popular shops, and you can see more of Panama City by jumping on the metro at Iglesia del Carmen Station or Vía Argentina. You might spend time checking out top sights like Via Espana and Iglesia del Carmen.
El Cangrejo
The ample dining options and casino gaming are top of the list for many visitors to El Cangrejo. A stop by Via Espana or Crown Casino might round out your trip.
San Francisco
San Francisco is noteworthy for its restaurants, and you can make a stop at top attractions like Multiplaza Pacific Mall and Calle 50.
Calidonia
Calidonia is a destination travellers like for its shopping, and you might hop aboard the metro at Estación Lotería or Santo Tomas Station to explore sights like Via Espana.
