Serra Mesa Travel Guide

Tourist Guide

A residential area with houses, roads, and a hilly landscape.

Stay near popular Serra Mesa attractions

Civita Dog Park

After visiting Civita Dog Park, make a plan to see the other sights and activities in San Diego.
See properties

Activities

San Diego Afternoon Sail

Spectacular Afternoon Sail on San Diego Bay

AU$167
per adult
Spectacular Afternoon Sail on San Diego Bay
San Diego Whale Watching Tour

San Diego Whale Watching & Dolphin Cruise

AU$99
per adult
88% of travellers recommend
San Diego Whale Watching & Dolphin Cruise
San Diego Old Town Trolley Hop-On Hop-Off Tour

San Diego Old Town Trolley Hop-On Hop-Off Tour

AU$79
per adult
94% of travellers recommend
San Diego Old Town Trolley Hop-On Hop-Off Tour
San Diego City Lights Night Tour

San Diego City Lights Night Tour

AU$62
per adult
96% of travellers recommend
San Diego City Lights Night Tour
San Diego: Mission Bay Sunset Cruise

San Diego: Mission Bay Sunset Cruise

AU$60
per adult
84% of travellers recommend
San Diego: Mission Bay Sunset Cruise
San Diego: Luggage Storage in Marina

San Diego: Luggage Storage in Marina

AU$16
per adult
80% of travellers recommend
San Diego: Luggage Storage in Marina
See all activities in San Diego

Our pick of the best Serra Mesa Hotel Deals

Manchester Grand Hyatt San Diego

Manchester Grand Hyatt San Diego

4 out of 5
1 Market Pl San Diego CA
The price is AU$396 per night from 8 Sept to 9 Sept
AU$396
8 Sept - 9 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy 6 restaurants, 3 bars/lounges and breakfast (surcharge). Our guests praise the pool and the helpful ...
9/10 Wonderful! (2,854 reviews)
"Really enjoyed the property, the bar on the 40th was very cool"

Reviewed on 7 Sept 2026

Manchester Grand Hyatt San Diego
California Suites Hotel

California Suites Hotel

2 out of 5
5415 Clairemont Mesa Blvd San Diego CA
The price is AU$128 per night from 20 Sept to 21 Sept
AU$128
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, free parking and a 24-hour front desk. Our guests praise the helpful staff and the clean ...
7.8/10 Good! (2,938 reviews)
"Clean room and Staff"

Reviewed on 7 Sept 2026

California Suites Hotel
Wyndham San Diego Bayside

Wyndham San Diego Bayside

4 out of 5
1355 N Harbor Drive San Diego CA
The price is AU$293 per night from 20 Sept to 21 Sept
AU$293
20 Sept - 21 Sept
includes taxes & fees
Stay at this business-friendly hotel in San Diego. Enjoy free Wi-Fi, 3 restaurants and breakfast (surcharge). Our guests praise the pool and the restaurant in ...
8.4/10 Very good! (6,323 reviews)
"The hotel is old and smelled grungy. I asked for a room away from noise and received a room next to the elevator with chimed all night. I would not recommend this hotel especially for the price."

Reviewed on 7 Sept 2026

Wyndham San Diego Bayside
Paradise Point Resort & Spa

Paradise Point Resort & Spa

4 out of 5
1404 Vacation Rd San Diego CA
The price is AU$381 per night from 8 Sept to 9 Sept
AU$381
8 Sept - 9 Sept
includes taxes & fees
Stay at this beach resort in San Diego. Enjoy free Wi-Fi, 5 outdoor pools and a full-service spa. Our guests praise the pool and the helpful staff in their reviews. ...
Paradise Point Resort & Spa
The Dana on Mission Bay

The Dana on Mission Bay

3.5 out of 5
1710 W Mission Bay Dr San Diego CA
The price is AU$291 per night from 5 Oct to 6 Oct
AU$291
5 Oct - 6 Oct
includes taxes & fees
Stay at this hotel in San Diego. Enjoy 2 outdoor pools, a marina and 2 hot tubs. Our guests praise the pool and the restaurant in their reviews. Popular attractions ...
The Dana on Mission Bay
The Sofia Hotel

The Sofia Hotel

3.5 out of 5
150 W Broadway San Diego CA
The price is AU$261 per night from 28 Sept to 29 Sept
AU$261
28 Sept - 29 Sept
includes taxes & fees
Stay at this historic hotel in San Diego. Enjoy free Wi-Fi, breakfast (surcharge) and room service. Our guests praise the helpful staff and the clean rooms in ...
The Sofia Hotel
See all 9,209 properties in Serra Mesa
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Our guide on where to stay in Serra Mesa

Find the best Serra Mesa areas for the activities you enjoy most.
A plaza with a traditional building, benches, and a large tree.

Downtown San Diego

Known for its fantastic nightlife, fascinating museums and beautiful waterfront views, there's plenty to explore in Downtown San Diego. Top attractions like Petco Park and Port of San Diego are major draws. Catch the metro at Civic Center Station or Civic Center Station to see more of the city.

A beach with surfers and swimmers during sunset.

Pacific Beach

The stunning beaches and fantastic nightlife are just a few highlights of Pacific Beach. Make a stop by Mission Bay or Pacific Beach while you're exploring the area.

A roller coaster under construction with scaffolding and a ticket booth in the foreground.

Mission Beach

If you're spending some time in Mission Beach, Mission Beach and Mission Bay are top sights worth seeing.

A theater marquee with ornate designs and the name "Gaslamp Quarter".

Gaslamp Quarter

Cosy bars interesting history and top sights from Gaslamp Museum at the Davis-Horton House to Harlem of the West Sites – discover Gaslamp Quarter, a destination also famous for its shopping.

An aerial view of a coastal city with a marina, a large body of water, and a peninsula with buildings.

Mission Bay

If you're spending some time in Mission Bay, Mission Bay and Mission and Pacific Beaches are top sights worth seeing.

Serra Mesa Travel Guide

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